A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V53938 | Tetramethylkaempferol | 16692-52-7 | Tetramethylkaempferol is an antifungal compound/agent. | |
V56288 | Thalifoline | 21796-15-6 | Thalifoline is an alkaloid with antifungal activity. | |
V56195 | Thiophanat-methyl-d6 (Thiophanate-methyl-d6) | 1398065-77-4 | Thiophanate-methyl-d6 is the deuterium labelled form of Thiophanate-methyl. | |
V53299 | Thiram-d12 | 69193-86-8 | Thiram-d12 is the deuterium labelled form of Thiram. | |
V54005 | TMV-IN-5 | 1207318-92-0 | TMV-IN-5 (Compound 1a) is an anti-plant virus/fungal agent. | |
V34715 | Tolindate | 27877-51-6 | Tolindate is a potent PXR agonist with EC50 of 8.3 µM. | |
V56369 | Tolnaftate-d7 (Tolnaftate-d7) | 1329835-64-4 | Tolnaftate-d7 is the deuterium labelled form of Tolnaftate. | |
V53958 | Toonacilatin M | 93930-04-2 | Toonaciliatin M (compound 6) is a diterpene compound extracted from Toona ciliate. | |
V54000 | Topazolin | 109605-79-0 | Topazolin is a flavonoid. | |
V56368 | Triadimenol-d4 | 2121989-56-6 | Triadimenol-d4 is the deuterium labelled form of Triadimenol. | |
V54002 | Triclopyricarb (SYP-7017) | 902760-40-1 | Triclopyricarb (SYP-7017) is a strobilurin fungicide used for crop disease control. | |
V53902 | Triflumizole | 68694-11-1 | Triflumizole is an imidazole fungicide that is extensively used to control powdery mildew and scab on a variety of fruits and crops by inhibiting ergosterol biosynthesis. | |
V41372 | Triticonazole | 131983-72-7 | Triticonazole is a triazole-based fungicidal agent as well as a pesticidewith broad antifungal andendocrine disrupting activities. | |
V35147 | Validamycin A (Jinggangmycin A) | 37248-47-8 | Validamycin A is a fungicide and agricultural antibiotic originally extracted from Streptomyces hygroscopicus var. limoneus | |
V54014 | Valtrate hydrine B4 | 18296-48-5 | Valtrate hydrine B4 is a natural compound with antifungal activity. | |
V53903 | Verazine ((-)-Verazine) | 14320-81-1 | Verazine ((-)-Verazine) is an antifungal agent obtained from the dried roots and rhizomes of Hellebore trichosanthes. | |
V52898 | Viridicatol (pure green penicillol) | 14484-44-7 | Viridicatol is a quinolone alkaloid extracted from fermentation of the endophytic fungus Penicillium spp. | |
V56373 | Voriconazole-d3 (UK-109496-d3) | 1217661-14-7 | Voriconazole-d3 is the deuterium labelled form of Voriconazole. | |
V53976 | Xanthobaccin A | 227596-81-8 | Xanthobaccin A is an antifungal compound extracted from the culture medium of Stenotrophomonas SB-K88 strain. | |
V35109 | Y18501 | 2410627-32-4 | Y18501 is an oxysterol-binding protein inhibitor (antagonist) with a similar structure to Oxathiapiprolin. |