Fungal

Fungal

A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.

Fungal related products

Structure Cat No. Product Name CAS No. Product Description
V53938 Tetramethylkaempferol 16692-52-7 Tetramethylkaempferol is an antifungal compound/agent.
V56288 Thalifoline 21796-15-6 Thalifoline is an alkaloid with antifungal activity.
V56195 Thiophanat-methyl-d6 (Thiophanate-methyl-d6) 1398065-77-4 Thiophanate-methyl-d6 is the deuterium labelled form of Thiophanate-methyl.
V53299 Thiram-d12 69193-86-8 Thiram-d12 is the deuterium labelled form of Thiram.
V54005 TMV-IN-5 1207318-92-0 TMV-IN-5 (Compound 1a) is an anti-plant virus/fungal agent.
V34715 Tolindate 27877-51-6 Tolindate is a potent PXR agonist with EC50 of 8.3 µM.
V56369 Tolnaftate-d7 (Tolnaftate-d7) 1329835-64-4 Tolnaftate-d7 is the deuterium labelled form of Tolnaftate.
V53958 Toonacilatin M 93930-04-2 Toonaciliatin M (compound 6) is a diterpene compound extracted from Toona ciliate.
V54000 Topazolin 109605-79-0 Topazolin is a flavonoid.
V56368 Triadimenol-d4 2121989-56-6 Triadimenol-d4 is the deuterium labelled form of Triadimenol.
V54002 Triclopyricarb (SYP-7017) 902760-40-1 Triclopyricarb (SYP-7017) is a strobilurin fungicide used for crop disease control.
V53902 Triflumizole 68694-11-1 Triflumizole is an imidazole fungicide that is extensively used to control powdery mildew and scab on a variety of fruits and crops by inhibiting ergosterol biosynthesis.
V41372 Triticonazole 131983-72-7 Triticonazole is a triazole-based fungicidal agent as well as a pesticidewith broad antifungal andendocrine disrupting activities.
V35147 Validamycin A (Jinggangmycin A) 37248-47-8 Validamycin A is a fungicide and agricultural antibiotic originally extracted from Streptomyces hygroscopicus var. limoneus
V54014 Valtrate hydrine B4 18296-48-5 Valtrate hydrine B4 is a natural compound with antifungal activity.
V53903 Verazine ((-)-Verazine) 14320-81-1 Verazine ((-)-Verazine) is an antifungal agent obtained from the dried roots and rhizomes of Hellebore trichosanthes.
V52898 Viridicatol (pure green penicillol) 14484-44-7 Viridicatol is a quinolone alkaloid extracted from fermentation of the endophytic fungus Penicillium spp.
V56373 Voriconazole-d3 (UK-109496-d3) 1217661-14-7 Voriconazole-d3 is the deuterium labelled form of Voriconazole.
V53976 Xanthobaccin A 227596-81-8 Xanthobaccin A is an antifungal compound extracted from the culture medium of Stenotrophomonas SB-K88 strain.
V35109 Y18501 2410627-32-4 Y18501 is an oxysterol-binding protein inhibitor (antagonist) with a similar structure to Oxathiapiprolin.
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