A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V56319 | Naftifine-d3 hydrochloride (Naftifine d3 hydrochloride) | 1246833-81-7 | Naftifine-d3 ( HCl) is the deuterated form of Naftifine HCl. |
|
V53905 | Naphthalene-2,3-Dicarboxaldehyde (2,3-Naphthalenedicarboxaldehyde; Naphthalene-2,3-dialdehyde) | 7149-49-7 | Naphthalene-2,3-Dicarboxaldehyde (2,3-Naphthalenedicarboxaldehyde), an o-phthalaldehyde analogue, is a fungal ASADH inhibitor (Ki: 45 μM). |
|
V53915 | Neocnidilide (Neocnidilide; Neocnidilide) | 4567-33-3 | Neocnidilide is an alkyl phthalate that has activity in inhibiting the growth of mycotoxin-producing fungi. |
|
V53909 | Neophellamuretin | 52589-20-5 | Neophellamuretin is a flavonoid. |
|
V35062 | Nourseothricin sulfate (streptothricin sulfate) | 96736-11-7 | Nourseothricin sulfate (Streptothricin sulfate) is a broad-spectrum antibiotic that disrupts the outer membrane of Gram-negative (Gram+) bacteria and is the primary selective marker for Fonsecaea pedrosoi. |
|
V4420 | Novolimus | 151519-50-5 | Novolimus is a novel and potent macrocyclic lactone with anti-proliferative properties, it has a similar efficacy to currently available agents but is efficacious at a lower dose and is therefore conceivably safer to use. |
|
V19623 | NSC-40738 | 67-47-0 | NSC-40738 is a novel and potent biochemical for treatment of sickle cell anemia. |
|
V54010 | Nudicaucin B | 211557-36-7 | Nudicaucin B is a triterpene saponin found in Hedyotis nudicaulis. |
|
V32994 | Nystatin | 1400-61-9 | Nystatin (Candex;Mycostatin;Barstatin 100; Biofanal;AI3-26526) is a potent polyeneantifungal antibiotic with abroad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notablyCandidaspecies. |
|
V53419 | Nystatin A3 (nystatin A3) | 62997-67-5 | Nystatin A3, produced from Streptomyces noursei, is a bioactive component of the nystatin complex. |
|
V34808 | o-Vanillin (2-Vanillin) | 148-53-8 | o-Vanillin (2-Vanillin) is a naturally occurring compound found in the fruit of Vanilla planifolia, Pinus koraiensis. |
|
V53911 | Orysastrobin | 248593-16-0 | Orysastrobin is a "quinone external inhibitor" (QoI) type fungicide with excellent fungicidal effect against rice leaf blast, ear blast and sheath blight. |
|
V52893 | Paclobutrazol (paclobutrazole; chlorobutrazole) | 76738-62-0 | Paclobutrazol is a triazole-containing plant growth retardant that can inhibit gibberellin biosynthesis. |
|
V80176 | Paclobutrazol-d4 (paclobutrazol-d4; chlorobutrazol-d4) | Paclobutrazol-d4 is the deuterium labelled form of Paclobutrazol. | |
|
V81033 | PAF26 | PAF26 is an antimicrobial peptide against the phytopathogenic fungi Penicillium digitatum, Penicillium italicum and Botrytis cinerea. | |
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V54028 | Pectate Lyase | 9015-75-2 | Pectate Lyase is an important enzyme secreted by plant pathogenic bacteria. |
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V53445 | Penconazole | 66246-88-6 | Penconazole is a typical triazole fungicide (fungicide), mainly used for the control of powdery mildew in apples, grapes, vegetables and other places. |
|
V52803 | Penconazole-d7 | 1628110-84-8 | Penconazole-d7 is the deuterated form of Penconazole. |
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V53930 | Penflufen | 494793-67-8 | Penflufen is a highly effective, broad-spectrum inhibitor of succinate dehydrogenase. |
|
V27269 | Penthiopyrad | 183675-82-3 | Penthiopyrad (MTF-753) is a chiral carboxamide antifungal compound/agent with broad spectrum (a wide range) bactericidal ( bacteria killing) activity. |
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