A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V81379 | SDH-IN-6 | SDH-IN-6 (compound 6i) is a potent succinate dehydrogenase (SDH) inhibitor. | |
|
V81380 | SDH-IN-7 | SDH-IN-7 (compound G28) is a potent succinate dehydrogenase (SDH) inhibitor (antagonist) with IC50 of 26 nM against porcine SDH. | |
|
V80021 | SDH-IN-8 | SDH-IN-8 (compound G40) is a potent succinate dehydrogenase (SDH) inhibitor (antagonist) with IC50 of 27 nM against porcine SDH. | |
|
V53370 | Sequosempervirin B | 864719-17-5 | Sequosempervirin B is a norlignan extracted from the branches and leaves of Sequoia sempervirens and has antifungal properties. |
|
V37017 | Seselin | 523-59-1 | Seselin is an anticancer, anti~inflammatory, and antifungal compound/agent that is orally bioactive. |
|
V53940 | Sikokianin A (4′-O-Demethylchamaejasmenin B) | 106293-99-6 | Sikokianin A is a bisflavonoid extracted from the roots of Stellera chamaejasme. |
|
V53783 | Sinigrin hydrate (potassium myrosinate monohydrate; sinigrin monohydrate) | 64550-88-5 | Sinigrin (hydrate) is a naturally occurring aliphatic glucosinolate found in Brassicaceae plants. |
|
V56035 | Sordarin sodium | 463356-00-5 | Sordarin is a potent bisbenzamide-dependent eEF2 inhibitor (antagonist) with antifungal properties. |
|
V53936 | SP-B peptide | 865714-65-4 | SP-B peptide is an antimicrobial peptide. |
|
V53970 | Spiroxamine | 118134-30-8 | Spiroxamine is a fungicide that may be utilized to sterilize grapes with low residue. |
|
V53966 | Stemphyperylenol | 102694-33-7 | Hypericol from stems and leaves has strong antifungal activity against tomato red spot pathogen, with MIC of 1.57 μM. |
|
V53993 | Static acid | 549-06-4 | Stictic acid is a secondary metabolite (SM, chemical compound) that can be extracted from the lichen Lobaria pulmonaria (L.) Hoffm. |
|
V35241 | Swinholide A | 95927-67-6 | Swinholide A is a marine polyketide that binds actin and dimerizes actin with a Kd of approximately 50 nM. |
|
V35239 | Syringomycin E | 124888-22-8 | Syringomycin E is an antifungal cyclic lipopeptide. |
|
V35233 | T-2307 | 873546-31-7 | T-2307 is an arylamidine with antifungal activity in vitro and in vivo. |
|
V56169 | Tebuconazole-d9 (tebuconazole d9) | 1246818-83-6 | Tebuconazole-d9 is the deuterated form of Tebuconazole. |
|
V56259 | Terconazole-d4 (R42470-d4) | 1398065-50-3 | Terconazole-d4 is the deuterated form of Terconazole. |
|
V81555 | Terpenomycin | Terpenomycin, a polyene found in isolates of the human pathogenic terpene Nocardia, has cytotoxic and antifungal activity. | |
|
V52890 | Tetraconazole | 112281-77-3 | Tetraconazole is a chiral triazole fungicide extensively used for disease control in wheat fields. |
|
V76249 | Tetrahydrorhombifoline | 3382-84-1 | TetraHydrorhombifoline is a quinolizidine alkaloid from the aerial parts of Genista vuralii A. Duran & H. Dural. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
