Dopamine Receptor

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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Dopamine Receptor

In the central nervous system (CNS) of vertebrates, dopamine receptors are a class of G protein-coupled receptors that are widely distributed. The main endogenous ligand for dopamine receptors is the neurotransmitter dopamine. Numerous neurological functions, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as the modulation of neuroendocrine signaling, are associated with dopamine receptors.Numerous neuropsychiatric disorders have abnormal dopamine receptor signaling and dopaminergic nerve function at their core. Dopamine receptors are therefore typical neurologic drug targets; psychostimulants are typically indirect agonists of dopamine receptors, whereas antipsychotics are frequently dopamine receptor antagonists. Dopamine receptors come in at least five different subtypes: D1, D2, D3, D4, and D5. The D2, D3, and D4 dopamine receptors are members of the D2-like family, whereas the D1 and D5 receptors belong to the D1-like family.

Dopamine Receptor related products

Cat No.	Product Name	CAS No.	Product Description
V1249	Chlorpromazine HCl	69-09-0	Chlorpromazine HCl (Promacid; Chloractil; Klorpromex; Fenactil; Largactil; Propaphenin; Sonazine; Thorazine), the Hydrochloride salt form of chlorpromazine, is a potent dopamine and potassium channel inhibitor used as an antipsychotic medication for the treatment of psychotic disorders such as schizophrenia.
V18228	Chlorprothixene HCl	6469-93-8	ChlorprothixeneHCl is a typical antipsychotic drug of the thioxanthene class and an antagonist of dopamine and histamine receptors such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively.
V1254	Metoclopramide HCl	7232-21-5	Metoclopramide HCl (Maxolon, AHR3070-C, AHR 3070-C, Metozolv, Reglan), the hydrochloride salt of Metoclopramide, is a potent and selective dopamine D2 receptor antagonist used as a medication for treating stomach and esophageal problems such as nausea and vomiting.
V1265	Ropinirole HCl	91374-20-8	Ropinirole HCl (formerly SKF 101468; SKF-101468A; SKF 101468A; Requip), the hydrochloride salt of ropinirole, is a potent and selective dopamine D2 receptors agonist ( Ki = 29 nM) of the non-ergoline class of medications used for PD-Parkinson's disease, RLS/restless legs syndrome and extrapyramidal symptoms.
V34121	rac-Rotigotine Hydrochloride	102120-99-0	rac-Rotigotine Hydrochloride is the racemic mixture of Rotigotine (N-0437; N-0923), which is a potent, non-selective and dopamine receptor full agonist, used in the treatment of Parkinson's disease and restless legs syndrome.
V14007	Rotigotine Hydrochloride	125572-93-2	RotigotineHydrochloride (N-0437; N-0923) is a potent, non-selective and dopamine receptor full agonist, used in the treatment of Parkinsons disease and restless legs syndrome.
V1257	Amantadine HCl	665-66-7	Amantadine HCl (EXP-105-1; GP 38026; ADS5102; Influenol; Midantan; Midantane; Mydantane; NSC 83653; Symadine; Symmetrel; Trivaline; Virasol; Viregyt; Virofral; Virosol),the hydrochloride salt of amantadine, is an approved medication used to treat or prevent infections of the respiratory tract caused by a certain virus.
V1255	Alizapride HCl	59338-87-3	Alizapride HCl (Limican; Plitican; Vergentan; Superan; Alizaprida; Litican; MS-5080), the hydrochloride salt of alizapride which is a medication used for the theropy of nausea and vomiting, is a potent dopamine receptor antagonist with prokinetic and antiemetic effects.
V8750	Ropinirole (SKF-101468)	91374-21-9	Ropinirole HCl (formerly SKF 101468; SKF-101468A; SKF 101468A; Requip), the hydrochloride salt of ropinirole, is a potent and selective dopamine D2 receptors agonist ( Ki = 29 nM) of the non-ergoline class of medications used for PD-Parkinson's disease, RLS/restless legs syndrome and extrapyramidal symptoms.
V1266	Lurasidone HCl (SM-13496)	367514-88-3	Lurasidone HCl (SM-13496; SM 13496; trade name Latuda), the hydrochloride salt of Lurasidone, is an atypical antipsychotic drug that has been approved for the treatment of schizophrenia and bipolar disorder.
V1253	Rotigotine (N-0437; N-0923)	99755-59-6	Rotigotine(formerly N-0437; N-0923; N0437; N0923; trade names Neupro among others) is a potent, non-selectivefull agonist of dopamine receptor that has been approved for use in the treatment of PD/Parkinsons disease and restless legs syndrome.
V29688	Fenoldopam (SKF 82526)	67227-56-9	Fenoldopam (SKF-82526) is a synthetic benzazepine analog acting as a selective D1 receptor partial agonist.
V15137	Spiperone	749-02-0	Spiperone (E-525; R-5147; Spiroperidol) is a novel and potent antipsychotic agent acting as adopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist with the potential for neurology diseases.
V15138	Spiperone HCl	2022-29-9	Spiperone HCl (NSC-170983; E-525; R-5147; Spiroperidol) is a novel and potent antipsychotic agent acting as a dopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist with the potential for neurology diseases.
V20614	Nomifensine Maleate	32795-47-4	Nomifensine Maleate, the maleate salt of nomifensine, is a novel, potent and selective dopamine uptake inhibitor interacting with the dopamine transporter at a site different from that of cocaine; antidepressan.
V17015	Nomifensine	24526-64-5	Nomifensine is an isoquinoline analoguethat prevents dopamine reuptake into synaptosomes.
V4975	Raclopride tartrate	98185-20-7	Raclopride (formerly also known as FLA 870) is a novel, potent and selective dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively.
V1271	Amisulpride (DAN 2163)	71675-85-9	Amisulpride (Solian; Amazeo; Amipride; Amival; Soltus; Aminosultopride; DAN-2163; DAN2163; Deniban; Amisulprida; Sulpitac; Sulprix) is a potent and atypical antipsychotic medication used to treat psychosis in schizophrenia and episodes of mania in bipolar disorders.
V29135	Raclopride (FLA-870)	84225-95-6	Raclopride (formerly FLA 870) is a novel, potent and selective dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively.
V18251	Fenoldopam mesylate (SKF82526)	67227-57-0	Fenoldopam mesyalte (SKF-82526) is a synthetic benzazepine analog acting as a selective D1 receptor partial agonist.