NF-κB

Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD
GPCR & G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase Adrenergic Receptor Angiotensin Receptor APJ Bombesin Receptor Bradykinin Receptor cAMP Cannabinoid Receptor CaSR CCK receptor CCR CGRP Receptor CRFR CXCR Dopamine Receptor EBI2 Endothelin Receptor Formyl Peptide Receptor Free Fatty Acid Receptor G protein-coupled Bile Acid Receptor GCGR GHSR GLP Receptor Glucagon Receptor GnRH Receptor GPCR19 GPR GPR109A Guanylate Cyclase Hedgehog(Smoothened) ROCK Histamine Receptor ICMT Leukotriene Receptor LPA Receptor LPL Receptor LTR mAChR Melanocortin Receptor Melatonin Receptor mGluR Motilin Receptor MRGPR MT Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor NPY receptor Opioid Receptor OX Receptor Oxytocin Receptor P2Y Receptor PAFR PAR PKD PKG Prostaglandin Receptor Ras RGS Protein S1P Receptor SGLT Sigma Receptor Somatostatin Receptor TAAR TSH Receptor Urotensin Receptor Vasopressin Receptor

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NF-κB

Nuclear factor-κB (NF-κB)/Rel proteins include NF-κB2 p52/p100, NF-κB1 p50/p105, c-Rel, RelA/p65, and RelB.These proteins perform as two-component transcription factors that control gene expression and have an impact on a variety of biological processes, such as innate and acquired immunity, inflammation, stress responses, B-cell development, and lymphoid organogenesis.The immune system's reaction to infection is significantly regulated by NF-B. In addition, the etiology of chronic inflammatory illnesses such inflammatory bowel disease, rheumatoid arthritis, and asthma is influenced by the activation of the NF-B pathway. Septic shock, autoimmune and inflammatory disorders, viral infections, and poor immunological development have all been connected to faulty NF-B regulation.

NF-κB related products

Cat No.	Product Name	CAS No.	Product Description
V80483	Keap1-Nrf2-IN-1 TFA		Keap1-Nrf2-IN-1 TFA (compound35) is a Keap1-Nrf2 protein-protein interaction inhibitor (antagonist) with IC50 of 43 nM for Keap1 protein.
V82287	L-Aspartic acid-13C4 (L-Aspartic acid 13C4)	55443-54-4	L-Aspartic acid-13C4 is 13C (carbon 13) labelled L-Aspartic acid.
V82279	L-Aspartic acid-13C4,15N (L-Aspartic acid 13C4,15N)	202468-27-7	L-Aspartic acid-13C4,15N is a 13C (carbon 13) and 15N (nitrogen 15) labelled L-Aspartic acid.
V82288	L-Aspartic acid-15N (L-Aspartic acid 15N)	3715-16-0	L-Aspartic acid-15N is a 15N (Nitrogen 15)-labelled L-Aspartic acid.
V82294	L-Serine-d2 ((-)-Serine-d2; (S)-Serine-d2)	95034-57-4	L-Serine-d2 is the deuterium labelled form of L-Serine.
V82277	Lacto-N-biose I (Galβ1-3GlcNAc)	50787-09-2	Lacto-N-biose I (Galβ1-3GlcNAc) α1,2-focusyltransferase enzyme receptor from Helicobacter pylori, an endogenously produced metabolite.
V2219	Laquinimod (ABR-215062)	248281-84-7	Laquinimod(also known as ABR-215062, LAQ) is a potent and orally bioactive immunoregulator being investigated for treatment of multiple sclerosis (MS).
V82296	Lasiocarpine	303-34-4	Lasiocarpine is a hepatotoxic pyrrolizidine alkaloid (hepatotoxic PA) that can cause fatal hepatic veno-occlusive disease in the body.
V82224	Licoagrochalcone C	325144-68-1	Licoagrochalcone C is a flavonoid with inhibitory activity on NF-κB transcription.
V82256	Lucioside B	91174-19-5	Lucyoside B inhibits the production of inflammatory mediators through the NF-κB and activator protein-1 pathways in activated macrophages.
V82293	N1,N8-Diacetylspermidine	82414-35-5	N1,N8-Diacetylspermidine is a polyamine found in human urine.
V26329	NDMC101	1308631-40-4	NDMC101 is a potent osteoclastogenesis inhibitor that can suppress osteoclast differentiation by downregulating NFATc1 regulatory gene expression.
V31378	Neferine	2292-16-2	Neferine is a bisbenzylisoquinoline alkaloid.
V28831	Neochlorogenic acid	906-33-2	Neochlorogenic acid is a natural polyphenolic compound with anti-inflammatory activity.
V75096	Neocryptotanshinone (新cryptotanshinone)	109664-02-0	Neocryptotanshinone is a salvia diterpene extracted from Salvia Miltiorrhiza, which inhibits lipopolysaccharide (LPS)-induced inflammation by inhibiting NF-κB and iNOS signaling.
V78749	NF-κB-IN-10		NF-κB-IN-10 (compound E1) is an NF-κB inhibitor that can reduce oxidative stress and inflammation by regulating the Nrf2/NF-κB signaling pathway, thereby improving heart failure.
V80940	NF-κB-IN-12		NF-κB-IN-12 (compound 3h) is a potent NF-κB inhibitor (antagonist) with IC50 of 1.02 μM.
V77644	NF-κB-IN-9		NF-κB-IN-9 is a sonosensitizer targeting nuclear factor NF-κB (λex/λem=489/628 nm).
V26503	NIK SMI1	1660114-31-7	NIK SMI1 (NIK-SMI1) is a novel, highly selective and potent inhibitor of NF-κB-inducing kinase (NIK).
V6034	Nimbolide	25990-37-8	Nimbolide is a naturally occuringtriterpene/limonoid isolated from the leaves and flowers of neem (Azadirachta indica L), acting as aninhibitor of pancreatic cancer growth and metastasis through ROS-mediated apoptosis.