NF-κB

Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD
GPCR & G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase Adrenergic Receptor Angiotensin Receptor APJ Bombesin Receptor Bradykinin Receptor cAMP Cannabinoid Receptor CaSR CCK receptor CCR CGRP Receptor CRFR CXCR Dopamine Receptor EBI2 Endothelin Receptor Formyl Peptide Receptor Free Fatty Acid Receptor G protein-coupled Bile Acid Receptor GCGR GHSR GLP Receptor Glucagon Receptor GnRH Receptor GPCR19 GPR GPR109A Guanylate Cyclase Hedgehog(Smoothened) ROCK Histamine Receptor ICMT Leukotriene Receptor LPA Receptor LPL Receptor LTR mAChR Melanocortin Receptor Melatonin Receptor mGluR Motilin Receptor MRGPR MT Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor NPY receptor Opioid Receptor OX Receptor Oxytocin Receptor P2Y Receptor PAFR PAR PKD PKG Prostaglandin Receptor Ras RGS Protein S1P Receptor SGLT Sigma Receptor Somatostatin Receptor TAAR TSH Receptor Urotensin Receptor Vasopressin Receptor

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NF-κB

Nuclear factor-κB (NF-κB)/Rel proteins include NF-κB2 p52/p100, NF-κB1 p50/p105, c-Rel, RelA/p65, and RelB.These proteins perform as two-component transcription factors that control gene expression and have an impact on a variety of biological processes, such as innate and acquired immunity, inflammation, stress responses, B-cell development, and lymphoid organogenesis.The immune system's reaction to infection is significantly regulated by NF-B. In addition, the etiology of chronic inflammatory illnesses such inflammatory bowel disease, rheumatoid arthritis, and asthma is influenced by the activation of the NF-B pathway. Septic shock, autoimmune and inflammatory disorders, viral infections, and poor immunological development have all been connected to faulty NF-B regulation.

NF-κB related products

Cat No.	Product Name	CAS No.	Product Description
V82281	Nrf2 activator-6	2728780-74-1	Nrf2 activator-6 is a tetrahydroisoquinoline compound that is an Nrf2 activator.
V80971	Nrf2 activator-8		Nrf2 activator-8 (compound 10e) is an Nrf2 activator (EC50=37.9 nM).
V78790	Nrf2 activator-9		Nrf2 activator-9 (compound D-36) is an Nrf2 activator that can inhibit oxidized low-density lipoprotein (oxLDL) and high glucose (HG)-induced apoptosis in HUVEC cells.
V82290	Nur77 antagonist 1	2378780-25-5	Nur77 antagonist 1(Compound ja) is a selective Nur77 antagonist.
V34237	Obtusifolin	477-85-0	Isolated from the Cassia obtusifolia seeds, Obtusifolin is natural product of the anthraquinone class.
V28683	Ophiopogonin D	945619-74-9	Ophiopogonin D is a novel and potent C29 steroidal glycoside.
V5343	Parthenolide	20554-84-1	Parthenolide, formerly known as NSC-157035, is a novel sesquiterpene lactone isolated from the medicinal herb Feverfew, acting as a NF-κB activation inhibitor potentially for the treatment of cancer.
V82262	Penicitide A	1338332-27-6	Penicitide A is a marine secondary metabolite (SM, chemical compound).
V81188	Praelolide		Praelolide is a potent Nrf2 activator.
V82278	Pregnanediol 3-glucuronide	1852-49-9	Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone and plays an important role in physiological processes such as the female menstrual cycle, pregnancy (supporting pregnancy), embryogenesis, and maternal immune responses in humans and other species.
V81250	PTD-p65-P1 Peptide		PTD-p65-P1 Peptide is a potent and specific inhibitor of the nuclear transcription factor NF-κB, derived from the p65 subunit of NF-κB amino acid (AA) residues 271-282.
V76581	PTD-p65-P1 Peptide TFA		PTD-p65-P1 Peptide TFA is a potent and specific inhibitor of the nuclear transcription factor NF-κB, derived from the p65 subunit of NF-κB amino acid (AA) residues 271-282, which can selectively inhibit NF induced by various inflammatory stimuli.
V3143	Pyrrolidinedithiocarbamate ammonium	5108-96-3	Ammonium pyrrolidine dithiocarbamate (also abbreviated as PDTC) is a potentnuclear factor-κB (NF-κB)inhibitor.
V60047	Regaloside A	114420-66-5	Regaloside A is a novel a phenylpropanoid with anti-inflammatory properties and a significant amount of DPPH radical scavenging activity (58.0% at 160 ppm).
V78377	S217879		S217879 is a highly efficient and selective NRF2 activator.
V0769	SC75741	913822-46-5	SC75741 (SC-75741; SC 75741) is a novel,selective and potent NF-κB inhibitor with potential antiviral and anti-inflammatory activity.
V14531	Schisantherin A	58546-56-8	Schisantherin A is a lignan.
V82292	Selenocystine	2897-21-4	Selenocystine is a broad-spectrum anticancer agent.
V79845	Siegesbeckialide I		Siegesbeckialide I potently inhibits LPS-induced NO production in RAW264.7 cells by directly binding to IKKα/β.
V40026	Sinomenine	115-53-7	Sinomenine, a naturally occuringalkaloid isolated from the root of the plant Sinomenium acutum, is a blocker of the NF-κB activation with anticancer and anti-inflammatory effects.