| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V0854 | Leflunomide | 75706-12-6 | Leflunomide (formerly also known as HWA486; Leflunomidum, trade/brand name Arava)is a potent pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug), it is used as an immunosuppressant agent for treating inflammatory conditions such as RA-rheumatoid arthritis. |
|
V0856 | MK-8245 | 1030612-90-8 | MK-8245 (MK8245; MK 8245) is a novel and potentliver-targeted inhibitor of stearoyl-CoA desaturase (SCD) with anti-diabetic and anti-dyslipidemic activities. |
|
V0852 | Mycophenolate Mofetil | 128794-94-5 | Mycophenolate Mofetil (Cellcept, Mycophenolic acid, Myfortic, RS-61443), an antimetabolite immunosuppressant,is a potent,non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively. |
|
V0858 | NCT-501 | 1802088-50-1 | NCT-501 (NCT501; NCT 501), a theophylline-based compound, is a novel, highly potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with potential anticancer activity. |
|
V26321 | NCT-503 | 1916571-90-8 | NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 of 2.5 µM. |
|
V5193 | Olutasidenib (FT2102) | 1887014-12-1 | Olutasidenib (FT-2102) is a novel, highly potent and selective small molecue inhibitor of mutant Isocitrate dehydrogenase 1 (IDH1) with the potential to be used in the treatment of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). |
|
V0863 | PluriSIn-1 (NSC 14613) | 91396-88-2 | PluriSIn-1 (PluriSln 1;NSC-14613; NSC14613;NSC 14613) is a pluripotent cell-specific inhibitor with important biological activity. |
|
V4546 | R-GNE-140 | 2003234-63-5 | (R)-GNE-140, the S-enantiomer ofGNE-140, is a novel and potent lactate dehydrogenase (LDHA) inhibitor with potential anticancer activity. |
|
V0857 | SW-033291 | 459147-39-8 | SW033291 (SW-033291; SW 033291) is a selective and high affinity inhibitor of the prostaglandin-degrading enzyme 15-PGD (15-hydroxyprostaglandin dehydrogenase) with potential kidney and liver protective effects. |
|
V0867 | Teriflunomide | 108605-62-5 | Teriflunomide (formerly HMR-1726; HMR1726;A771726; A-771726; trade name Aubagio), the active metabolite of theimmunomodulator drug-leflunomide, is an orally bioavailableimmunomodulatory agent with potential suppressing effects against immune systems. |
|
V0860 | Trilostane | 13647-35-3 | Trilostane (also known as WIN 24540; Desopan; DB-011080; Win-24540; Modrastane)is a potent inhibitor of 3β-hydroxysteroid dehydrogenase that was used in the treatment of Cushings syndrome,Conns syndrome, and postmenopausal breast cancer in humans. |
|
V0861 | Vidofludimus | 717824-30-1 | Vidofludimus (4SC101; SC-12267;SC12267, 4SC-101;4SC 101; SC 12267) is a novel, potent and orally bioactive/bioavailable inhibitor of dihydroorotate dehydrogenase (DHODH) withpotentialanti-inflammatory,immunomodulatingandanti-viralactivities. |
|
V2766 | Vorasidenib | 1644545-52-7 | Vorasidenib (formerly known as AG-881; AG881) is a selective and orally bioavailable inhibitor of mutated forms of both isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) with potential anticancer activity. |
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