Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V72134 | 3,4,5-Trimethoxyphenylacetic acid | 951-82-6 | 3,4,5-Trimethoxyphenylacetic acid is a metabolite of Mescaline. |
|
V72120 | 3,4-Dehydro Cilostazol (OPC-13015) | 73963-62-9 | 3,4-Dehydro Cilostazol (OPC-13015) is the bioactive metabolite of cilostazol (CLZ). |
|
V72232 | 3-(1-Nitrosopyrrolidin-2-yl)pyridine | 80508-23-2 | 3-(1-Nitrosopyrrolidin-2-yl)pyridine is a major tobacco-specific nitrosamine. |
|
V72118 | 3-Amino-2-oxazolidinone (AOZ) | 80-65-9 | 3-Amino-2-oxazolidinone (AOZ) is the metabolite of furazolidinone. |
|
V71650 | 3-Hydroxycarbofuran (3-Hydroxycarbofuran) | 16655-82-6 | 3-Hydroxycarbofuran is the major metabolite of Carbofuran and is a reversible inhibitor of acetylcholinesterase (AChE). |
|
V72211 | 3-Hydroxyphenazepam | 70030-11-4 | 3-Hydroxyphenazepam is the bioactive metabolite of Cinazepam. |
|
V72171 | 3-Methyl-2-quinoxalinecarboxylic acid (MQCA) | 74003-63-7 | 3-Methyl-2-quinoxalinecarboxylic acid (MQCA) is an important N-oxide reducing metabolite of Quinocetone or Olaquindox, which can effectively suppress the growth of Zhang's hepatocytes through S-phase cell cycle arrest. |
|
V72160 | 3-O-Methyl-6β-naltrexone | 65150-66-5 | 3-O-Methyl-6β-naltrexone is a metabolite of naltrexone. |
|
V72256 | 4′-Dihydrophaseic acid | 41756-77-8 | 4′-Dihydrophaseic acid is an abscisic acid metabolite. |
|
V72235 | 4'-Hydroxy diclofenac-13C6 (4'-Hydroxydiclofenac-13C6) | 1189656-64-1 | 4'-Hydroxy diclofenac-13C6 is 13C (carbon 13)-labeled 4'-Hydroxy diclofenac. |
|
V72115 | 4'-Hydroxy diclofenac-d4 | 254762-27-1 | 4'-Hydroxy diclofenac-d4 is the deuterated form of 4'-Hydroxy diclofenac. |
|
V9099 | 4'-Hydroxydiclofenac | 64118-84-9 | 4'-Hydroxydiclofenac is an active CYP2C9-mediated metabolite of diclofenac which is potent nonsteroidal anti-inflammatory drug (NSAID) anda Cox-2 inhibitor. |
|
V67688 | 4'-Hydroxytamoxifen | 82413-23-8 | 4'-Hydroxytamoxifen is a metabolite of Tamoxifen. |
|
V40039 | 4-Desmethyl Istradefylline | 160434-48-0 | 4-Desmethyl Istradefylline is the demethylated metabolite of Istradefylline （KW-6002; Nourianz), which is an orally bioavailable adenosine A2A receptor (A2AR) antagonist approved for the treatment of PD (Parkinson's disease). |
|
V72136 | 4-Epioxytetracycline | 14206-58-7 | 4-Epioxytetracycline is a degradation product of Oxytetracycline and is found in pig manure compost and wastewater. |
|
V72263 | 4-Hydroxy Atorvastatin lactone (P-Hydroxyatorvastatin lactone; 4-ATL) | 163217-70-7 | 4-Hydroxy Atorvastatin lactone is the metabolite of Atorvastatin. |
|
V72203 | 4-Hydroxy-3-methoxyamphetamine hydrochloride | 13062-61-8 | 4-Hydroxy-3-methoxyamphetamine HCl is a metabolite of 3,4-methylenedioxymethamphetamine (MDMA). |
|
V72231 | 4-Hydroxylidocaine | 39942-41-1 | 4-Hydroxylidocaine is a metabolite of Lidocaine. |
|
V29894 | 4-Hydroxymephenytoin | 61837-65-8 | 4-Hydroxymephenytoin is a metabolite of the antiepileptic agent mephenytoin; mephenytoin is a ligand of CYP2C19. |
|
V72109 | 4-Hydroxymephenytoin-d3 (hydroxycoumarin-d3) | 1173022-56-4 | 4-Hydroxymephenytoin-d3 is the deuterated form of 4-Hydroxymephenytoin. |
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