Drug Metabolite

Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD
GPCR & G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase Adrenergic Receptor Angiotensin Receptor APJ Bombesin Receptor Bradykinin Receptor cAMP Cannabinoid Receptor CaSR CCK receptor CCR CGRP Receptor CRFR CXCR Dopamine Receptor EBI2 Endothelin Receptor Formyl Peptide Receptor Free Fatty Acid Receptor G protein-coupled Bile Acid Receptor GCGR GHSR GLP Receptor Glucagon Receptor GnRH Receptor GPCR19 GPR GPR109A Guanylate Cyclase Hedgehog(Smoothened) ROCK Histamine Receptor ICMT Leukotriene Receptor LPA Receptor LPL Receptor LTR mAChR Melanocortin Receptor Melatonin Receptor mGluR Motilin Receptor MRGPR MT Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor NPY receptor Opioid Receptor OX Receptor Oxytocin Receptor P2Y Receptor PAFR PAR PKD PKG Prostaglandin Receptor Ras RGS Protein S1P Receptor SGLT Sigma Receptor Somatostatin Receptor TAAR TSH Receptor Urotensin Receptor Vasopressin Receptor

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Drug Metabolite

Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.

Drug Metabolite related products

Cat No.	Product Name	CAS No.	Product Description
V72288	Monoethyl phthalate	2306-33-4	Monoethyl phthalate, a metabolite of diethyl phosphate, can serve as a urinary biomarker of phthalate exposure, indicating the risk of thyroid cancer and benign nodules.
V72131	Monoethylglycinexylidide hydrochloride (MEGX hydrochloride; Norlidocaine hydrochloride)	7729-94-4	Monoethylglycinexylidide (MEGX) HCl is a metabolite of Lidocaine produced through oxidative metabolism by cytochrome P-450 enzymes in the liver.
V72237	Mosapride N-Oxide	1161443-73-7	Mosapride N-Oxide is the main bioactive metabolite of mosapride.
V72106	MTIC (temozolomide metabolite - MTIC)	3413-72-7	MTIC is the bioactive metabolite of Temozolomide (TMZ).
V72112	Mycophenolic acid glucuronide	31528-44-6	Mycophenolic acid glucuronide is a metabolite of the immunosuppressant mycophenolic acid.
V72193	N-(2-Hydroxyethyl)oxamic acid	5270-73-5	N-(2-hydroxyethyl)-oxamic acid is formed by the chemical or intestinal bacterial reduction of Metronidazole.
V72224	N-Acetyl dapsone (MADDS; Monoacetyldapsone)	565-20-8	N-Acetyl dapsone (MADDS) is the major metabolite of dapsone.
V72191	N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid; N-Acetyl-ASA)	51-59-2	N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is a metabolite of 5-Aminosalicylic Acid and has endoscopic activity.
V72284	N-Carbethoxy-4-piperidone	29976-53-2	N-Carbethoxy-4-piperidone is a metabolite of Loratadine.
V67748	N-Demethyl Mifepristone (RU 42633)	104004-96-8	N-Demethyl Mifepristone (RU 42633) is the bioactive metabolite of Mifepristone.
V72220	N-Demethylerythromycin A (N-Demethylerythromycin A)	992-62-1	N-Demethylerythromycin A is a metabolite of Erythromycin A.
V72170	N-Desalkyludenafil	319491-68-4	N-Desalkyludenafil is a metabolite of Udenafil.
V30776	N-Desethyl Sunitinib (SU-11662)	356068-97-8	N-Desethyl Sunitinib(SU-11662) is a major metabolite of sunitinib which is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with Kis of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively.
V76713	N-Desethyl Sunitinib hydrochloride (SU-12662 hydrochloride)		N-Desethyl Sunitinib (SU-12662) ( HCl) is a metabolite of Sunitinib.
V72277	N-Desmethyl imatinib mesylate (Norimatinib mesylate; Imatinib metabolite N-Desmethyl imatinib mesylate)	404844-03-7	N-Desmethyl imatinib mesylate (Norimatinib mesylate) is a metabolite of Imatinib.
V72239	N-Desmethyl zopiclone-d8	1189805-43-3	N-Desmethyl zopiclone-d8 is the deuterium labelled form of Norzopiclone.
V72153	N-Methyl Palbociclib (impurity of palbociclib)	571189-51-0	N-Methyl Palbociclib is an impurity of Palbociclib.
V72229	N-Methyl pemetrexed (Pemetrexed Impurity A)	869791-42-4	N-Methyl pemetrexed is an impurity in Pemetrexed.
V72129	N-Methyl-4-pyridone-3-carboxamide	769-49-3	N-Methyl-4-pyridone-3-carboxamide is a metabolite of caffeopyridine.
V72226	N-Nitrosoglyphosate sodium (N-Nitroso-N-(phosphonoMethyl)glycine sodium; Glyphosate-N-nitroso sodium)	56516-71-3	N-Nitrosoglyphosate sodium is a degradation product of nitrosamines and a synthetic impurity in glyphosate herbicides.