Drug Metabolite

Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD
GPCR & G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase Adrenergic Receptor Angiotensin Receptor APJ Bombesin Receptor Bradykinin Receptor cAMP Cannabinoid Receptor CaSR CCK receptor CCR CGRP Receptor CRFR CXCR Dopamine Receptor EBI2 Endothelin Receptor Formyl Peptide Receptor Free Fatty Acid Receptor G protein-coupled Bile Acid Receptor GCGR GHSR GLP Receptor Glucagon Receptor GnRH Receptor GPCR19 GPR GPR109A Guanylate Cyclase Hedgehog(Smoothened) ROCK Histamine Receptor ICMT Leukotriene Receptor LPA Receptor LPL Receptor LTR mAChR Melanocortin Receptor Melatonin Receptor mGluR Motilin Receptor MRGPR MT Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor NPY receptor Opioid Receptor OX Receptor Oxytocin Receptor P2Y Receptor PAFR PAR PKD PKG Prostaglandin Receptor Ras RGS Protein S1P Receptor SGLT Sigma Receptor Somatostatin Receptor TAAR TSH Receptor Urotensin Receptor Vasopressin Receptor

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Drug Metabolite

Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.

Drug Metabolite related products

Cat No.	Product Name	CAS No.	Product Description
V72163	Pseudoerythromycin A enol ether (LY267108)	105882-69-7	Pseudoerythromycin A enol ether (LY267108) is a degradation product of erythromycin.
V72151	Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide)	38934-20-2	Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a metabolite of Quercetin, can be extracted from the Uncarina species in Madagascar.
V72146	Quetiapine sulfoxide hydrochloride (quetiapine sulfoxide hydrochloride; Quetiapine S-oxide hydrochloride)	2448341-72-6	Quetiapine sulfoxide HCl (Quetiapine S-oxide HCl) is the major metabolite of Quetiapinem.
V72248	Radafaxine ((S,S)-Hydroxybupropion; GW-353162A free base; BW-306U free base)	192374-14-4	Radafaxine ((S,S)-Hydroxybupropion) is an antidepressant compound.
V70587	Ramelteon metabolite M-II-d3	1246812-22-5	Ramelteon metabolite M-II-d3 is the deuterium labelled form of Ramelteon metabolite M-II.
V69537	Regorarafénib N-oxyde-d3(M2) (Regorafénib N-oxide (M2 metabolite) impurity 13-d3)	1333489-03-4	Regorafénib N-oxyde-d3(M2) is the deuterated form of Regorafénib N-oxyde M2.
V72175	Resveratrol-3-O-sulfate sodium	858127-11-4	Resveratrol-3-O-sulfate (sodium) is a metabolite of Resveratrol.
V72276	Ritalinic acid (Ritalinic acid; Ritalinate)	19395-41-6	Ritalinic acid (Ritalinate) is the major inactive urinary metabolite of Methylphenidate.
V72213	Rosuvastatin lactone	503610-43-3	Rosuvastatin lactone is a metabolite of rosuvastatin, an HMG-CoA inhibitor.
V72157	RP101075	1306760-73-5	RP101075, the bioactive metabolite of Ozanimod, is a potent oral S1PR1 agonist/activator with EC50 of 0.27 nM.
V72241	RP101442	1306761-08-9	RP101442, the bioactive metabolite of Ozanimod, is a selective S1PR1 agonist/activator with EC50s of 2.6 nM and 171 nM for S1PR1 and S1PR5, respectively.
V76549	RP101988		RP101442 is the main bioactive metabolite of Ozanimod and a selective S1PR1 agonist/activator with EC50s of 0.19 nM and 32.8 nM for S1PR1 and S1P5R respectively.
V76548	RPR132595A hydrochloride (NPC hydrochloride)		RPR132595A (NPC) HCl is the bioactive metabolite of CPT-11, which is produced by cytochrome P-450 3A4 (CYP3A4) and is ultimately excreted in the urine.
V72172	S-Allylmercapturic acid	23127-41-5	S-Allylmercapturic acid is a biomarker of garlic consumption food intake (BFI).
V72298	Seco Rapamycin (Secorapamycin; Secorapamycin A)	147438-27-5	Seco Rapamycin (Secorapamycin A) is the open-ring metabolite of Rapamycin.
V76525	Seco Rapamycin ethyl ester		Seco Rapamycin ethyl ester is the open-ring metabolite of Rapamycin.
V76496	Sofosbuvir impurity B (sofosbuvir impurity B)		Sofosbuvir impurity B is an impurity in Sofosbuvir.
V76495	Sofosbuvir impurity D		Sofosbuvir impurity D is an impurity in Sofosbuvir.
V76494	Sofosbuvir impurity E (sofosbuvir impurity E)		Sofosbuvir impurity E is an impurity in Sofosbuvir.
V72199	T-705RMP	356783-08-9	T-705RMP is the phosphorylated metabolite of T-705 and has a weak inhibitory effect on host cell IMP dehydrogenase (IMPDH) activity, with IC50 of 601 μM.