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Reactive Oxygen Species

Reactive Oxygen Species

Reactive oxygen species (ROS) are radical and non-radical oxygen species produced by the partial reduction of oxygen, including superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•). Endogenous ROS are produced by cells during their normal oxidative metabolism in the mitochondria as well as when they react to xenobiotics, cytokines, and bacterial invasion.

By directly inhibiting MAPK phosphatases, ROS also activates MAPK pathways. Through PTEN, ROS produced by growth factor stimulation are capable of reversibly controlling the redox state of the PI3K pathway. The cellular response to ROS may involve the activation of autophagy.

Reactive Oxygen Species related products

Structure Cat No. Product Name CAS No. Product Description
Mesotrione V72952 Mesotrione 104206-82-8 Mesotrione is a benzoylcyclohexanedione herbicide.
Mesuol V72936 Mesuol 16981-20-7 Mesuol is a naturally occurring compound extracted from M.
Methylophiopogonone B (Methylophiopogonone B) V72905 Methylophiopogonone B (Methylophiopogonone B) 74805-89-3 Methylophiopogonone B is an isoflavone extracted from Ophiopogonis Tiber that scavenges •OH and H2O2.
MitoB-d15 bromide V102885 MitoB-d15 bromide MitoB-d15(bromide) is a deuterated MitoB(bromide).
Mitochondrial respiration-IN-4 V86997 Mitochondrial respiration-IN-4 Mitochondrial respiration-IN-4 (Compound TC11) is a potent mitochondrial respiration inhibitor.
Mitoquinol V87703 Mitoquinol 845959-55-9 Mitoquinol is a mitochondrial-targeted coenzyme Q analog.
Mitoquinol-d15 V102842 Mitoquinol-d15 Mitoquinol-d15 is a deuterated mitoquinol.
MitoTEMPOL V101223 MitoTEMPOL 1101113-39-6 MitoTEMPOL is a mitochondrial-targeted nitric oxide that reduces mitochondrial O2- to H2O2.
MSU38225 V72942 MSU38225 1629160-83-3 MSU38225 is an Nrf-2 inhibitor that increases reactive oxygen species (ROS) levels.
Myr-Tat-PKCβII V106271 Myr-Tat-PKCβII Myr-Tat-PKCβII is a cell-permeable peptide protein kinase CβII inhibitor.
N,N'-Dimethylthiourea (N,N-dimethylthiourea; DMTU) V72884 N,N'-Dimethylthiourea (N,N-dimethylthiourea; DMTU) 534-13-4 N,N'-Dimethylthiourea (DMTU), extracted from black garlic, is an orally bioavailable and effective scavenger of hydroxyl radicals (•OH), preventing the production of •OH in vitro by activated neutrophils.
N-Acetyl-D-cysteine V72883 N-Acetyl-D-cysteine 26117-28-2 N-Acetyl-D-cysteine has anti-oxidant effect and scavenges ROS by reacting with sulfhydryl groups, but it cannot enter the glutathione metabolic pathway.
N-Acetyl-L-cysteine ethyl ester (N-Acetylcysteine ethyl ester; NACET) V72879 N-Acetyl-L-cysteine ethyl ester (N-Acetylcysteine ethyl ester; NACET) 59587-09-6 N-Acetyl-L-cysteine ethyl ester is the esterified form of NAC.
N-Acetyldopamine dimer-2 V72920 N-Acetyldopamine dimer-2 916888-49-8 N-Acetyldopamine dimer-2 (compound 2) is an N-acetyldopamine dimer with antioxidant and anti-inflammatory activity that can be extracted from the yellow powder of cicada bark.
N-Methyl-2-HOBA hydrochloride V106824 N-Methyl-2-HOBA hydrochloride 63989-87-7 N-Methyl-2-HOBA (2-((methylamino)methyl)phenol) hydrochloride is the methylated form of the isoketone scavenger 2-HOBA.
N-tert-Butyl-α-phenylnitrone V72889 N-tert-Butyl-α-phenylnitrone 3376-24-7 N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitric oxide spin adducts.
N-tert-Butyl-α-phenylnitrone-d14 (N-tert-butyl-α-phenylnitrone-d14) V72972 N-tert-Butyl-α-phenylnitrone-d14 (N-tert-butyl-α-phenylnitrone-d14) 119391-92-3 N-tert-Butyl-α-phenylnitrone-d14 is the deuterium labelled form of N-tert-Butyl-α-phenylnitrone.
N-trans-Caffeoyltyramine V72891 N-trans-Caffeoyltyramine 103188-48-3 N-trans-Caffeoyltyramine is a potent inflammatory response modulator with anti-oxidant effect and anticoagulant effects.
N1-Acetyl-5-methoxykynuramine hydrochloride V107214 N1-Acetyl-5-methoxykynuramine hydrochloride 1215711-91-3 N1-Acetyl-5-methoxykynurenine (AMK) hydrochloride is the active metabolite of the neurohormone melatonin.
NAE-IN-1 V87639 NAE-IN-1 NAE-IN-1 (compound X-10) is a potent NAE1 inhibitor.
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