A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V53946 | Chitin synthase inhibitor 14 | 2922114-19-8 | Chitin synthase inhibitor 14 (compound 4n) is an inhibitor (blocker/antagonist) of chitin synthase (CHS). |
|
V76268 | Chitin synthase inhibitor 9 | 2725074-96-2 | Chitin synthase inhibitor 9 is a chitin synthase (CHS) inhibitor (antagonist) with broad-spectrum antifungal activity. |
|
V53949 | Chloramultilide B | 1000995-47-0 | Chloramultilide B is an indene dimer that can be extracted from Chloranthus serratus. |
|
V15826 | Chlorothalonil | 1897-45-6 | Chlorothalonil (Daconil; DAC 2787;Tetrachloroisophthalodinitrile; Perchloroisophthalonitrile) is abroad spectrum antifungal agent and fungicide with carcinogenic and aquatic toxicity properties. |
|
V52532 | Chlorothalonil-13C2 | 2767332-24-9 | Chlorothalonil-13C2 is 13C (carbon 13) labelled Chlorothalonil. |
|
V0186 | Ciclopirox (HOE 296) | 29342-05-0 | Ciclopirox (HOE-296; LACQUER; Penlac), ahydroxypyrimidine analog, is an potent, synthetic and broad-spectrum antifungal agent used for topical dermatologic treatment of superficial mycoses. |
|
V56371 | Climbazole-d4 (BAY-e 6975-d4) | 1185117-79-6 | Climbazole-d4 is the deuterated form of Climbazole. |
|
V18488 | Clioquinol | 130-26-7 | Clioquinol (Iodochlorhydroxyquin) is a neurotoxic antibiotic, an antifungal drug and antiprotozoal agent that is effective against Alzheimer's disease/AD and can induce cancer cell death. |
|
V76272 | Columbianetin | 1147-29-1 | Columbianetin is a phytoalexin implicated in celery resistance to pathogens during storage. |
|
V53103 | Colutehydroquinone | 181311-16-0 | Colutehydroquinone is an isoflavone found in the root bark of Colutea arborescens. |
|
V4160 | Coniferyl alcohol | 458-35-5 | Coniferyl alcohol is an important intermediate used in biosynthesis of eugenol and of stilbene and coumarin. |
|
V53922 | Corymbosin (corymbosin) | 18103-41-8 | Corymbosin is a glycoside. |
|
V53285 | Cyclo(L-Leu-L-Pro) (Cyclo(L-prolyl-L-leucyl)) | 2873-36-1 | Cyclo (L-Leu-L-Pro) is a substance that can inhibit the production of dehydrochloric acid (NA, the precursor of aflatoxin) and can be extracted from Achromobacter xylosoxidans NFRI-A1. |
|
V54033 | Cyclo(L-leucyl-L-valyl) | 15136-24-0 | Cyclo(L-leucyl-L-valyl) inhibits the production of aflatoxin by Aspergillus parasiticus. |
|
V52207 | Cyclo(L-Phe-L-Val) | 35590-86-4 | Cyclo(L-Phe-L-Val) is a potent inhibitor of isocitrate lyase (ICL) (IC50=27μg/mL). |
|
V18969 | Cyclosporin C | 59787-61-0 | Cyclosporin C is a naturally occuring and highly lipophilic cyclic peptide, a member of the cyclosporin series of antifungal and immunosuppresive compounds - Cyclosporin A and B. |
|
V53000 | Cymoxanil (cymoxanil) | 57966-95-7 | Cymoxanil is a fungicide used to control plant diseases caused by downy mildew fungi. |
|
V56370 | Cymoxanil-d3 (cymoxanil-d3) | 2140803-92-3 | Cymoxanil-d3 is the deuterium labelled form of Cymoxanil. |
|
V53984 | Cytochalasin R | 121964-47-4 | Cytochalasin R (compound 17) is a cytochalasin (Cytochalasin) analogue that can be extracted from the endophytic fungus Phomopsis sp. xz-18. |
|
V52202 | D75-4590 | 384376-42-5 | D75-4590 is an inhibitor (blocker/antagonist) of pyridine benzimidazole analogues and β-1,6-glucan synthesis with antifungal activity. |
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