Fungal

Fungal

A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.

Fungal related products

Structure Cat No. Product Name CAS No. Product Description
V53828 Avenaciolide 26057-70-5 Avenaciolide is an antifungal di-γ-lactone found in Aspergillus avenaceus.
V53956 Bac2A TFA 231306-42-6 Bac2A TFA is an antimicrobial and immunomodulatory peptide.
V5560 Basifungin 127785-64-2 Aureobasidin A (Basifungin) is a cyclic peptide and antifungal antibiotic.
V76270 Benzovindiflupyr 1072957-71-1 Benzovindiflupyr is a succinate dehydrogenase inhibitor (SDHI).
V53969 Benzyl 2-hydroxy-6-methoxybenzoate 24474-71-3 Benzyl 2-hydroxy-6-methoxybenzoate has strong antifungal effect, with IC50 of 25–26 μg/mL against fungal strains.
V4209 Bifonazole 60628-96-8 Bifonazole (Bifomyk;Bay H-4502; Bifokey;Bifon) is a potent imidazole-based antifungal drug with abroad-spectrum of antimycotic activity by interfering with sterol biosynthesis.
V53058 Boscalid 188425-85-6 Boscalid is an antifungal compound/agent.
V53950 BTL peptide 1021461-47-1 BTL peptide is an antibacterial peptide that has anti-bacterial effect against B. maydis, A. brassicae, A. niger and C. personata.
V53914 Buclosamide 575-74-6 Buclosamide is a topical antifungal compound/agent.
V52311 Bulnesol 22451-73-6 Bulnesol is a sesquiterpenoid that can be extracted from Salvia miltiorrhiza.
V4052 Caerulomycin A 21802-37-9 Caerulomycin A (also known as Cerulomycin, CaeA) is a novel bipyridyl compound that induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling.
V56261 Carbendazim-d4 (Carbendazim d4) 291765-95-2 Carbendazim-d4 is the deuterated form of Carbendazim.
V53996 Carviolin 478-35-3 Carviolin is a compound extracted from the mycelium of the ascomycete Neobulgaria pura.
V2511 Caspofungin Acetate (MK0991) 179463-17-3 Caspofungin acetate (formerly known as MK-0991; trade name: Cancidas), a cyclic lipopeptide, is a new class of antifungal drug.
V54027 Cerbinal (gardenaldehyde) 65597-42-4 Cerbinal is a natural compound extracted from gardenia.
V54018 Chamaejasmenin D 865852-47-7 Chamaejasmenin D is an antimitotic and antifungal compound/agent.
V76267 Chitin synthase inhibitor 10 2725075-01-2 Chitin synthase inhibitor 10 is a chitin synthase (CHS) inhibitor.
V76274 Chitin synthase inhibitor 11 2725075-04-5 Chitin synthase inhibitor 11 is a chitin synthase (CHS) inhibitor.
V76263 Chitin synthase inhibitor 12 2725075-05-6 Chitin synthase inhibitor 12 is a chitin synthase (CHS) inhibitor.
V53943 Chitin synthase inhibitor 13 2925228-79-9 Chitin synthase inhibitor 13 (compound 12g) is a noncompetitive inhibitor of chitin synthase with IC50 of 106.7 μM.
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