A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V53992 | Antifungal agent 66 | 1613152-33-2 | Antifungal agent 66 (compound 10) has antifungal activity. |
|
V53945 | Antifungal agent 67 | 2925307-52-2 | Antifungal agent 67 (compound 9) is an imidazole antifungal agent that is effective against Candida. |
|
V53937 | Antifungal agent 68 | 2925307-53-3 | Antifungal agent 68 (compound 10) is an antifungal agent against Candida and Cryptococcus gattii. |
|
V53998 | Antifungal agent 69 | 2925307-56-6 | Antifungal agent 69 (compound 13) is a eugenol-imidazole active against Candida albicans with an MIC of 4.6 μM and no associated cytotoxic effect. |
|
V53982 | Antifungal agent 70 | 2925307-57-7 | Antifungal agent 70 (compound 13) is a dihydroeugenol-imidazole active against multidrug-resistant Candida auris with an MIC of 36.4 μM. |
|
V79493 | Antifungal agent 71 | Antifungal agent 71 (compound 6r) is a trifluoromethylpyrimidine analogue with antifungal activity. | |
|
V78004 | Antifungal agent 72 | Antifungal agent 72 (Compound B8) is an effective antifungal agent. | |
|
V53989 | Antifungal agent 73 | 2923519-78-0 | Antifungal agent 73 (compound A32) is an antifungal agent for treating azole-resistant candidiasis. |
|
V56287 | Antifungal agent 74 | 2856379-97-8 | Antifungal agent 74 (compound 3c) is a potent antifungal agent that displays excellent bactericidal activity against C. arachidicola and R. solani. Antifungal agent 74 exerts its bactericidal activity by disrupting steroid biosynthesis and ribosome biogenesis in eukaryotes. |
|
V78005 | Antifungal agent 75 | Antifungal agent 75 (compound 6r) is an effective antifungal agent against Candida albicans. | |
|
V34822 | Antifungal agent 76 | 1615683-57-2 | Antifungal agent 76 (compound 23h) has potent antifungal activity and a broad antifungal spectrum with MICs as low as 0.25-16 μg/mL. |
|
V76262 | Antifungal agent 77 | 2863678-89-9 | Antifungal agent 77 (Compound 13h) is an antifungal agent. |
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V80028 | Antifungal agent 78 | antifungal compound/agent 78 (compound 25am) is an antifungal compound/agent with EC50 of 13.46 μM against Fusarium graminearum. | |
|
V79824 | Antifungal agent 81 | Antifungal agent 81(G22) has good in vitro anti-bacterial effect against Vibrio mali, with IC50 of 0.48 mg/L. | |
|
V78007 | Antifungal agent 82 | Antifungal agent 82 (compound G34) is an antifungal (fungal) agent. | |
|
V34857 | Antifungal agent 84 | 2901064-07-9 | Antibacterial agent 84 is an antifungal compound. |
|
V76276 | Antifungal agent 87 | 692730-21-5 | antifungal compound/agent 87(10) works as a highly efficient PDT antifungal photosensitizer (PDT-IC50 for T. |
|
V80064 | Antimicrobial agent-24 | antimicrobial compound-24 (compound E8) is a hydrazide compound with excellent broad-spectrum bactericidal activity. | |
|
V34828 | Antiproliferative agent-18 | 2882206-14-4 | antiproliferation agent-18 (Compound 5k) is an antiproliferation agent that also has moderate anti-bacterial and anti-fungi activity. |
|
V53964 | Asperfuran | 129277-10-7 | Asperfuran is an antifungal dihydrobenzofuran analogue produced by Aspergillus oryzae strains. |
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