A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V77999 | Antifungal agent 45 | Antifungal agent 45 has bactericidal activity. | |
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V19251 | Antifungal agent 46 | 2842067-19-8 | Antifungal agent 46 (compound 2f) is an effective antifungal agent. |
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V78000 | Antifungal agent 47 | Antifungal agent 47 (compound 3b) showed the highest broad-spectrum fungicidal activity, strong respiratory inhibitory activity and adenosine 5'-triphosphate synthesis inhibitory activity. | |
|
V34827 | Antifungal agent 48 | 2142003-75-4 | Antifungal agent 48 (Example 112) is an antifungal agent. |
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V34826 | Antifungal agent 49 | 1414861-21-4 | Antifungal agent 49 (Example 112) is an antifungal agent. |
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V53952 | Antifungal agent 50 | 2896209-33-7 | antifungal compound/agent 50 is an antifungal compound/agent with a MIC of <0.063-1 μg/mL. |
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V34824 | Antifungal agent 51 | 2896209-47-3 | Antifungal agent 51 (Compound 5c) has potent antifungal activity, especially against Candida albicans FDC 151, Candida parapsilosis ATCC 22019 and Candida tropicalis FDC 138. |
|
V30051 | Antifungal agent 52 | 2901064-06-8 | Antifungal agent 52 (compound 6c) is a tetrazole analogue. |
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V34823 | Antifungal agent 53 | 2422019-76-7 | Antifungal agent 53 (A03) is a potent Candida albicans CYP51 inhibitor (antagonist) with antifungal activity. |
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V54009 | Antifungal agent 54 | 2422019-78-9 | Antifungal agent 54 (compound A05) is a potent antifungal agent against fluconazole resistant strains. |
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V54015 | Antifungal agent 55 | 2422019-80-3 | Antifungal agent 55 (compound A07) is a potent antifungal agent against fluconazole resistant strains. |
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V53948 | Antifungal agent 56 | 2422019-82-5 | Antifungal agent 56 (compound A09) is a potent antifungal agent against fluconazole resistant strains. |
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V53957 | Antifungal agent 57 | 2422019-92-7 | Antifungal agent 57 (compound A19) is a potent antifungal agent against fluconazole resistant strains. |
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V53971 | Antifungal agent 58 | 2422019-94-9 | Antifungal agent 58 (compound A21) is a potent antifungal agent against fluconazole resistant strains. |
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V34825 | Antifungal agent 59 | 2422019-96-1 | Antifungal agent 59 is an antifungal agent with a MIC of 0.01-1 μg/mL. |
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V54017 | Antifungal agent 6 | 332849-40-8 | antifungal compound/agent 6 is an anti-bacterial agent. |
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V79482 | Antifungal agent 60 | Antifungal agent 60 (compound 16) is an ergosterol biosynthesis inhibitor (antagonist) with broad-spectrum antifungal activity. | |
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V79887 | Antifungal agent 61 | Antifungal agent 61 (Compound 38) is an antifungal agent. | |
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V78003 | Antifungal agent 64 | Antifungal agent 64 (Compound 5c) is a fungicide with high fungicidal effects against Fusarium oxysporum f.sp. cucumerinum | |
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V53974 | Antifungal agent 65 | 1223550-31-9 | Antifungal agent 65 (Compound 5d) is a fungicide with high fungicidal effects against Fusarium oxysporum f.sp. cucumerinum. |
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