A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V11268 | AN2718 | 174672-06-1 | AN2718 is a novel boron-containing small molecule that inhibits an essential protein synthesis enzyme, leucyl-transfer RNA synthetase, or LeuRS. |
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V1916 | Anidulafungin (LY303366) | 166663-25-8 | Anidulafungin (formerly also named as LY303366; Eraxis; Ecalta), a novel semisynthetic echinocandin derivative, which inhibits glucan synthase activity,used as an antifungal drug. |
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V52416 | Anisocoumarin H | 123237-86-5 | Anisocoumarin H is a coumarin with antifungal activity. |
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V53917 | Anpocogin | 2725767-44-0 | Anpocogin is a c2 variant of the anticoagulant protein (with the addition of C-terminal P85) of the nematode Ancyclostoma canium. |
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V53910 | Antibacterial agent 157 | 2573134-85-5 | Antibacterial agent 157 (compound B12) is a fungicide. |
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V53961 | Antifungal agent 11 | 2966848-10-0 | antifungal compound/agent 11 has good antifungal activity. |
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V54003 | Antifungal agent 12 | 2966848-11-1 | antifungal compound/agent 12 is a new type of fluconazole compound with good antifungal activity. |
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V54001 | Antifungal agent 13 | 2834776-94-0 | antifungal compound/agent 13 has significant antifungal activity against Sclerotinia sclerotiorum with EC50 of 1.25 mg/L. |
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V53955 | Antifungal agent 14 | 2710259-38-2 | antifungal compound/agent 14 displays broad spectrum (a wide range) activity against fungal strains with excellent minimum inhibitory concentration values. |
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V53942 | Antifungal agent 15 | 2639531-53-4 | Antifungal agent 15 had the strongest antifungal activity against S. sclerotiorum and B. cinerea, with EC50s of 0.52 and 0.50 μg/mL respectively. |
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V53991 | Antifungal agent 16 | 2762034-41-1 | antifungal compound/agent 16 showed comparable anti-bacterial effect and excellent antifungal activity compared to ciprofloxacin and fluconazole, respectively. |
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V77996 | Antifungal agent 17 | antifungal compound/agent 17 has excellent antifungal properties against B. | |
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V53999 | Antifungal agent 18 | 2572713-30-3 | antifungal compound/agent 18 is a new antifungal compound/agent studied in fungal infections. |
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V79948 | Antifungal agent 19 | antifungal compound/agent 19 showed potent antifungal activity (EC50 = 0.72 μM). | |
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V53919 | Antifungal agent 20 | 2460281-94-9 | Antifungal agent 20 has significant antifungal activity against Colletotrichum gloeosprioides, Rhizoctonia solani, Phytophthora nicotianae var. |
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V53987 | Antifungal agent 21 | 1622299-33-5 | antifungal compound/agent 21 is a promising candidate compound for the development of new agrochemical antifungal compound/agents. |
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V76275 | Antifungal agent 26 | 2769834-78-6 | Antifungal agent 26 is a sulfamycin an analogue that displays antifungal, antiviral and antiparasitic activities via binding to d-mannose (Man)-containing glycans in pathogenic bacteria. |
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V76265 | Antifungal agent 39 | 2725074-94-0 | antifungal compound/agent 39 (Compound 9h) is a broad spectrum antifungal (antifungal) agent. |
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V77997 | Antifungal agent 41 | Antifungal agent 41 (compound B01) is an antifungal agent. | |
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V77998 | Antifungal agent 44 | Antifungal agent 44 (compound 2A-5) is a bacteriostatic agent with better anti-bacterial effect than Kresoxim-methyl. |
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