A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V56263 | 2-Phenylethyl isothiocyanate-d5 (2-PE ITC-d5) | 912627-98-6 | 2-Phenylethyl isothiocyanate-d5 is the deuterated form of 2-Phenylethyl isothiocyanate. |
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V53273 | 3,5-Di-tert-butylphenol | 1138-52-9 | 3,5-Di-tert-butylphenol is a volatile organic/chemical reagent with antibiofilm and antifungal activity. |
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V53921 | 3-Oxobetulin | 7020-34-0 | 3-Oxobetulin is an antifungal agent with antifungal activity against both the white rot fungus L. betulina and the brown rot fungus L. sulphureus. |
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V76271 | 3α,22β-Dihydroxyolean-12-en-29-oic acid | 808769-54-2 | 3α,22β-Dihydroxyolean-12-en-29-oic acid is a terpenoid extracted from Maytenus royleanus cufodontis. |
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V53534 | 4-Chlorocinnamic acid (p-chlorophenyl acrylic acid) | 1615-02-7 | 4-Chlorocinnamic acid has an inhibitory effect on tyrosinase. |
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V52881 | 4-Isopropylbenzoic acid | 536-66-3 | 4-Isopropylbenzoic acid is an aromatic monoterpene extracted from the stem bark of Bridelia retusa. |
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V53090 | 4-Methylcinnamic acid | 1866-39-3 | 4-Methylcinnamic acid, a cinnamic acid analog, may be used as an intervention catalyst to overcome antifungal resistance. |
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V52498 | 4-O-Methylsappanol (4-O-methyllignin) | 104778-16-7 | 4-O-Methylsappanol is a natural isoflavone with antifungal activity. |
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V53848 | 5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione | 36140-65-5 | 5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione (Compound 4) has antibacterial, antidiabetic, and antioxidant activities. |
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V53926 | 5-epi-Jinkoheremol | 2567930-96-3 | 5-epi-Jinkoheremol has stronger fungicidal activity than validamycin. |
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V53965 | 5-Heptadec-cis-8-enylresorcinol | 52483-19-9 | 5-Heptadec-cis-8-enylresorcinol is a 5-alkylresorcinol that can be extracted from etiolated rice seedlings. |
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V76260 | 6-Chloro-7-deazapurine-β-D-riboside | 16754-80-6 | Chloro-7-deazapurine-β-D-riboside is a nucleoside analogue with antifungal activity. |
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V29225 | Acetyllovastatin | 81189-92-6 | Acetyllovastatin is the acetated form of Lovastatinacetate of Lovastatin, which is a statin drug for hyperlipidemia. |
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V54012 | Aflatoxin Q1 | 52819-96-2 | Aflatoxin Q1 is the hydroxy metabolite of Aflatoxin B1 (AFB1), a mycotoxin produced by Aspergillus flavus (A. flavus). |
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V76024 | Ajoene | 92285-01-3 | Ajoene is a garlic-derived compound that is an antithrombotic and antifungal agent. |
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V10758 | Alexidine Dihydrochloride | 1715-30-6 | Alexidine dihydrochloride is an anticancer agent that targets a mitochondrial tyrosine phosphatase. |
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V53951 | Alterlactone | 1030376-89-6 | Alterlactone is an antibacterial agent. |
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V52423 | Aminocandin (HMR 3270; IP960; NXL201) | 227472-48-2 | Aminocandin (HMR 3270) is a water-soluble (H2O-soluble) echinocandin antifungal compound/agent (antifungal) with good activity against Aspergillus and Candida spp. |
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V2088 | Amorolfine HCl (Ro 14-4767/002) | 78613-38-4 | Amorolfine HCl (Ro 14-4767/002), a topically administered drug, is a potent and broad-spectrum antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts. |
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V6552 | Amphotericin B | 1397-89-3 | Amphotericin B (Fungizone; Amfocan; Ambisome;NSC527017;Amphozone; Fungilin; Amfocare; Amfotex; Amfotex) is a naturally occurringpolyene antifungal agent approved for treating serious fungal infections and leishmaniasis, such as mucormycosis, coccidioidomycosis,candidiasis,aspergillosis, blastomycosis, and cryptococcosis. |
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