The ion channel known as the calcium channel exhibits selective permeability to calcium ions. Although there are ligand-gated calcium channels as well, it is sometimes referred to as a voltage-dependent calcium channel. Even though the concentration of Na+ outside of cells is 70 times higher than that of Ca2+, voltage-gated calcium (CaV) channels catalyze a rapid, highly selective influx of Ca2+ into cells. A side effect of some calcium channel blockers is that they slow your heart rate, which helps to lower blood pressure, treat angina, and regulate irregular heartbeats.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V81772 | Ziconotide TFA (SNX-111 TFA) | Ziconotide TFA (SNX-111 TFA) is a bioactive peptide that is a potent and specific antagonist blocker of N-type calcium channels. | ||
V71542 | α2δligand 1 | 313653-15-5 | α2δ ligand 1 is from patent US20040186177, which is a ligand for the voltage-sensitive calcium channel α2δ-1. | |
V71496 | β-Cyfluthrin (beta-Cyfluthrin) | 1820573-27-0 | Beta-Cyfluthrin (beta-Cyfluthrin) is a type II synthetic pyrethroid and the active ingredient in many insecticide products used in agriculture to treat insect pests. | |
V81818 | γ-Glutamylserine TFA (γ-Glu-Ser TFA) | γ-Glutamylserine TFA (γ-Glu-Ser TFA) is a calcium receptor agonist/activator. | ||
V71498 | ω-Agatoxin IVA | 145017-83-0 | ω-Agatoxin IVA is a potent and specific P/Q-type Ca2+ (Cav2.1) channel blocker with IC50 of 2 nM and 90 nM for P-type and Q-type Ca2+ channels, respectively. | |
V81827 | ω-Agatoxin IVA TFA | ω-Agatoxin IVA TFA is a potent and specific P/Q-type Ca2+ (Cav2.1) channel blocker with IC50 of 2 nM and 90 nM for P-type and Q-type Ca2+ channels, respectively. | ||
V71479 | ω-Agatoxin TK | 158484-42-5 | ω-AgatoxinTK, a peptidyl toxin in the venom of Agelenopsis aperta, is an effective and selective P/Q-type Ca2+ channel blocker. | |
V81828 | ω-Conotoxin Bu8 | ω-Conotoxin Bu8 is an ω-conotoxin consisting of 25 amino acid (AA) residues and 3 disulfide bridges. | ||
V71502 | ω-Conotoxin CnVIIA | 760212-36-0 | ω-Conotoxin CnVIIA is a 27-amino acid (AA) neuropeptide toxin and an N-type calcium current blocker. | |
V71523 | ω-Conotoxin CVIA | 325164-06-5 | ω-Conotoxin CVIA is a 27-amino acid (AA) neuropeptide toxin and a voltage-sensitive calcium channel blocker. | |
V71530 | ω-Conotoxin CVID (Leconotide; AM336; CNSB004) | 247207-64-3 | ω-Conotoxin CVID (Leconotide, AM336, CNSB004) blocks neuronal voltage-sensitive calcium channels. | |
V81829 | ω-Conotoxin CVIE | ω-Conotoxin CVIE is a voltage-gated calcium channel (Ca v 2.2) selective inhibitor. | ||
V81830 | ω-Conotoxin CVIF | ω-Conotoxin CVIF is a selective Cav2.2 channel inhibitor (antagonist) with IC50 of 34.3 nM in isolated rat DRG neurons. | ||
V81831 | ω-Conotoxin FVIA | ω-Conotoxin FVIA is an N-type calcium channel (Ca v 2.2) inhibitor. | ||
V57221 | ω-Conotoxin GVIA TFA | ω-Conotoxin GVIA TFA is an N-type calcium channel (Ca2+ channel) inhibitor. | ||
V81832 | ω-conotoxin MoVIA | ω-conotoxin MoVIA is a potent and specific Cav2.2 inhibitor (antagonist) with IC50 of 0.33 μM in the SH-SY5Y fluorescence hCav2.2 assay. | ||
V42130 | ω-Conotoxin MVIIC TFA (ω-Conotoxin MVIIC TFA) | ω-Conotoxin MVIIC TFA is an N- and P/Q-type calcium channel (Ca2+ channel) blocker that can significantly block 11-keto-βboswellic acid-mediated inhibition of glutamate release. | ||
V81833 | ω-Conotoxin MVIID (SNX-238) | ω-Conotoxin MVIID (SNX-238) is a conopeptide that blocks ω-Conotoxin-GVIA-sensitive high-threshold Ca2+ currents in fish retinal ganglion cells. | ||
V71499 | ω-Conotoxin SO3 | 441284-32-8 | ω-Conotoxin SO3 is a blocker of N-type voltage-sensitive calcium channels. | |
V71526 | ω-Grammotoxin SIA (GrTx; ω-GsTx SIA) | 152617-90-8 | ω-Grammotoxin SIA (GrTx) is an inhibitor (blocker/antagonist) of P/Q and N-type voltage-gated Calcium Channels. |