Opioid ligands are a class of G protein-coupled receptors known as opioid receptors. Dynorphins, enkephalins, endorphins, endomorphins, and nociceptin are examples of endogenous opioids. There are many opioid receptors in the brain, as well as in the spinal cord and digestive system. The body has molecules or sites called opioid receptors that are triggered by opioid substances. Opioid receptors prevent impulses from traveling along excitatory pathways in the human body.The serotonin, catecholamine, and substance P pathways are some of these pathways, and they are all thought to play a role in pain perception and feelings of wellbeing. Mu, delta, and kappa receptors are additional subclassifications of opioid receptors. While each class has its own unique way of acting, they all have some fundamental things in common. The potassium pump mechanism, which is present on the plasma membrane of most cells, powers them all.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V69909 | mu opioid receptor agonist 3 | 2378397-91-0 | μ opioid receptor agonist 3 (compound 20) is a potent μ opioid receptor (μOR) agonist/activator with EC50 of 0.87 nM. |
|
V69938 | Mu opioid receptor antagonist 1 | 2767446-03-5 | Mu opioid receptor antagonist 1 (compound 19) is a selective and orally bioactive mu opioid receptor (MOR) ligand with a Ki of 0.58 nM and EC50 of 1.15 nM. |
|
V69910 | Mu opioid receptor antagonist 2 | 2773925-64-5 | Mu opioid receptor antagonist 2 (compound 25) is a specific and BBB (blood-brain barrier) permeable (penetrable) mu opioid receptor (MOR) antagonist (inhibitor) with a Ki of 0.37 nM and EC50 of 0.44 nM. |
|
V69947 | Mu opioid receptor antagonist 3 | 2773925-66-7 | Mu opioid receptor antagonist 3 (compound 26) is a potent and specific mu opioid receptor (MOR) antagonist (inhibitor) with a Ki of 0.24 nM and EC50 of 0.54 nM. |
|
V69948 | Mu opioid receptor antagonist 4 | 2773925-74-7 | Mu opioid receptor antagonist 4 (compound 31) is a potent and specific mu opioid receptor (MOR) antagonist (inhibitor) with EC50 of 1.07 nM and a Ki of 0.38 nM. |
|
V69940 | Mu opioid receptor antagonist 5 | 1124167-61-8 | Mu opioid receptor antagonist 5 (compound NAP) is a selective and BBB (blood-brain barrier) permeable (penetrable) mu opioid receptor (MOR) antagonist (inhibitor) with EC50 of 1.14 nM and a Ki of 0.37 nM. |
|
V69925 | Mu opioid receptor antagonist 7 | 2378397-30-7 | Mu opioid receptor antagonist 7 (compound 24) is a potent and CNS-permeable (penetrable) μOR (μ-opioid receptor) antagonist (inhibitor) with IC50 of 29 ± 3.0 nM. |
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V69921 | N-Benzylnaltrindole hydrochloride | 1206487-81-1 | N-Benzylnaltrindole HCl is a potent delta 2-selective opioid receptor antagonist. |
|
V69976 | N-terminally acetylated Leu-enkephalin (Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH) | 2703746-32-9 | N-terminally acetylated Leu-enkephalin is N-terminally acetylated Leu-enkephalin. |
|
V69884 | Naloxone methiodide | 93302-47-7 | Naloxone methiodide is a peripherally restricted, non-selective and competitive opioid receptor blocker (antagonist). |
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V69962 | Naloxone-d5 | 1261079-38-2 | Naloxone D5 is a deuterated compound standard of naloxone. |
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V69880 | Naltrexone | 16590-41-3 | Naltrexone is an Opioid receptor antagonist. |
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V69971 | Naltrexone-d4 (naltrexone D4) | 2070009-29-7 | Naltrexone-d4 is the deuterium labelled form of Naltrexone. |
|
V78367 | NAQ | NAQ is a potent and specific partial agonist of the mu-opioid receptor with a Ki of 0.55 nM. | |
|
V1274 | Nitrendipine (BAY-E-5009) | 39562-70-4 | Nitrendipine (BAY-E5009; BAY E-5009; Bayotensin; Bayotensin, Baypress, Nidrel, Deiten) is a potent dihydropyridine (DHP) calcium channel blocker (CCB) with antihypertensive effects. |
|
V76693 | Nociceptin (1-13), amide TFA | Nociceptin (1-13), amide TFA is a potent opioid receptor ORL1 (OP4) receptor agonist/activator with pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for rat forebrain membrane binding. | |
|
V69968 | Nociceptin(1-7) | 178249-42-8 | Nociceptin(1-7) is the N-terminal bioactive fragment of Nociceptin. |
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V80961 | Nociceptin(1-7) TFA | Nociceptin(1-7) is the N-terminal bioactive fragment of Nociceptin. | |
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V69956 | Nocistatin | 207392-60-7 | Nocistatin is a neuropeptide and endogenous ligand for orphan opioid receptors. |
|
V69929 | O-Desmethyl Tramadol-d6 | 873928-73-5 | O-Desmethyl Tramadol-d6 is the deuterated form of O-Desmethyl Tramadol. |
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