Angiotensin II serves as the ligand for the class of G protein-coupled receptors known as angiotensin receptors. They play a crucial role in the renin-angiotensin system as they are involved in the signal transduction of the main effector hormone, angiotensin II's, vasoconstricting stimulus. Angiotensin II, their primary ligand, has a similar affinity for the AT1 and AT2 receptors. The angiotensin receptor that has been most thoroughly characterized is AT1. The fetus and newborn have a higher concentration of AT2 receptors. The AT3 and AT4 receptors are additional understudied subtypes.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V77186 | Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) | Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) is a polypeptide containing 32 amino acid (AA)s. | |
|
V11787 | AT2 Agonist C21 (M24) | 477775-14-7 | AT2 Agonist C21(M-24) is a novel, potent and selective agonist of angiotensin AT2 receptors with Ki values of 0.4 nM and >10 µM for the AT2 receptor and AT1 receptor, respectively. |
|
V77129 | C-Type Natriuretic Peptide (1-53), human TFA | C-Type Natriuretic Peptide (1-53), human TFA is the 1-53 fragment of C-type natriuretic peptide. | |
|
V33156 | Candesartan D4 (CV-11974 D4) | 1346604-70-3 | Candesartan D4 (CV-11974 D4) is the tetra-deuterated form (in the central phenyl ring) ofform of Candesartan (formerly TCV-116; CV-11974; Atacand), which is an angiotensin II receptor antagonist (AT II inhibitor) approved for treatinghypertension and congestive heart failure. |
|
V75295 | Candesartan-d5 (Candesartan d5) | 1189650-58-5 | Candesartan-d5 is the deuterium labelled form of Candesartan. |
|
V4098 | CGP-42112 | 127060-75-7 | CGP-42112(also known as CGP-42112A) is a novel, potent and selective Angiotensin-II subtype 2 receptor(AT2 R) agonist. |
|
V78838 | CNP-38 | CNP-38 is a C-type natriuretic peptide. | |
|
V75282 | Dehydro Olmesartan | 172875-98-8 | Dehydro Olmesartan is an analogue of Olmesartan. |
|
V19995 | Eprosartan (SKF-108566J) | 133040-01-4 | Eprosartan (formerly SKF-108566J; SKF108566; SKF 108566; Teveten; Futuran; Navixen; Regulaten) is a nonpeptide angiotensin II receptor antagonist that has been approved as an antihypertensive medication for the treatment of high blood pressure. |
|
V75299 | Eprosartan-d3 (Eprosartan d3) | 1185243-70-2 | Eprosartan-d3 is the deuterated form of Eprosartan. |
|
V75300 | FK-739 free base | 133052-30-9 | FK-739 (free base) is an angiotensin II type 1 (AT1) receptor antagonist that may be utilized in the study of hypertension. |
|
V51353 | GSK1820795A | 2650253-86-2 | GSK1820795A works as a telmisartan analogue and is an antagonist of hGPR132a. |
|
V75284 | H-Val-Pro-Pro-OH TFA | 2828433-08-3 | H-Val-Pro-Pro-OH (TFA), a milk-derived proline peptide analogue, is an inhibitor (blocker/antagonist) of angiotensin I-converting enzyme (ACE) with IC50 of 9 μM. |
|
V15311 | Irbesartan HCl | 329055-23-4 | Irbesartan HCl (formerly known as SR-47436 and BMS-186295) is a novel, highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM. |
|
V78933 | Irbesartan-d6 (Irbesartan d6) | Irbesartan-d6 is the deuterated form of Irbesartan. | |
|
V24404 | Losartan (DUP 89) | 114798-26-4 | Losartan (DuP-753) is a potent, selective, and non-peptide angiotensin II receptor antagonist, it competes with angiotensin II for bindingto AT1 receptors with IC50 of 20 nM. |
|
V40724 | Losartan Carboxylic Acid | 124750-92-1 | Losartan carboxylic acid (EXP-3174; EXP 3174; EXP3174) is a cytochrome P450-mediated carboxylic acid metabolite, and is an active metabolite of Losartan. |
|
V34101 | Losartan D4 | 1030937-27-9 | Losartan D4 (also called DuP753 D4; DuP-753 D4) is the tetra-deuterated form of losartan (Cozaar among others), which is an angiotensin II receptor antagonist and antihypertensive drug. |
|
V33431 | Losartan D4 Carboxylic Acid | 1246820-62-1 | Losartan D4 carboxylic acid (EXP3174 D4; EXP3174; EXP-3174) is the tetra-deuterated form of Losartan carboxylic acid, which is a cytochrome P450-mediated carboxylic acid metabolite, and is an antagonist of angiotensin II receptor and an approved antihypertensive drug. |
|
V75288 | Losartan-d2 (Losartan-d2; DuP-753-d2) | 1030936-22-1 | Losartan-d2 is the deuterated form of Losartan. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
