Angiotensin II serves as the ligand for the class of G protein-coupled receptors known as angiotensin receptors. They play a crucial role in the renin-angiotensin system as they are involved in the signal transduction of the main effector hormone, angiotensin II's, vasoconstricting stimulus. Angiotensin II, their primary ligand, has a similar affinity for the AT1 and AT2 receptors. The angiotensin receptor that has been most thoroughly characterized is AT1. The fetus and newborn have a higher concentration of AT2 receptors. The AT3 and AT4 receptors are additional understudied subtypes.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V29552 | Tranilast trans- | 70806-55-2 | trans-Tranilast (trans-MK-341) is an anti-allergy agent utilized in study/research of bronchial asthma, allergic rhinitis and atopic dermatitis. |
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V75302 | TRV055 | 25849-90-5 | TRV055, a G protein-biased agonist, is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). |
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V76393 | TRV055 hydrochloride | TRV055 HCl, a G protein-biased agonist, is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). | |
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V75281 | TRV056 | 812644-79-4 | TRV056 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). |
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V75292 | Valsartan-d3 (CGP 48933-d3) | 1331908-02-1 | Valsartan-d3 is the deuterium labelled form of Valsartan. |
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V75294 | Valsartan-d8 (CGP 48933-d8) | 1089736-72-0 | Valsartan-d8 is the deuterium labelled form of Valsartan. |
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V73481 | YS-49 monohydrate | YS-49 (monohydrate) is an activator of PI3K/Akt (a downstream target of RhoA) and reduces RhoA/PTEN activation in 3-methylcholine-treated cells. |
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