Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V77637 | 5'-O-DMTr-2'-O-MOE inosine 3'-P-methyl phosphonamidite | 5'-O-DMTr-2'-O-MOE inosine 3'-P-methyl phosphonamidite is an analogue of purine nucleoside. | |
|
V77848 | 5'-O-DMTr-3'-O-phthalimidopropyl cytidine | 5'-O-DMTr-3'-O-phthalimidopropyl cytidine is an analogue of purine nucleoside. | |
|
V77865 | 5'-O-DMTr-5-MedC (Ac)-methyl phosphonamidite | 5'-O-DMTr-5-MedC (Ac)-methyl phosphonamidite is an analogue of purine nucleoside. | |
|
V77953 | 5'-O-DMTr-N6-ethyl-2'-deoxyadenosine | 5'-O-DMTr-N6-ethyl-2'-deoxyadenosine is an analogue of purine nucleoside. | |
|
V77638 | 5'-O-DMTr-N6-ethyl-2'-deoxyadenosine 3'-CED phosphoramidite | 5'-O-DMTr-N6-ethyl-2'-deoxyadenosine 3'-CED phosphoramidite is an analogue of purine nucleoside. | |
|
V78160 | 5-(2,3,5-Tri-O-benzyl-beta-D-ribofuranosyl)-2(1H)-pyridinone | 5-(2,3,5-Tri-O-benzyl-beta-D-ribofuranosyl)-2(1H)-pyridinone is an analogue of purine nucleoside. | |
|
V80308 | 5-(2-Azidoethyl)cytidine | 5-(2-Azidoethyl)cytidine is a cytosine nucleoside analog. | |
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V80305 | 5-(2-Azidoethyl)uridine | 5-(2-Azidoethyl)uridine is an analogue of purine nucleoside. | |
|
V78591 | 5-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine | 5-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine is an analogue of purine nucleoside. | |
|
V80600 | 5-(3-Azidopropyl)cytidine | 5-(3-Azidopropyl)cytidine is a cytosine nucleoside analog. | |
|
V80163 | 5-(t-Butyloxycarbonylmethoxy)uridine | 5-(t-Butyloxycarbonylmethoxy)uridine is a uridine analog. | |
|
V77641 | 5-Amino-2'-deoxy-2'-O-methyluridine hydrochloride | 5-Amino-2'-deoxy-2'-O-methyluridine HCl is a uridine analog. | |
|
V77533 | 5-Aza-xylo-cytidine | 5-Aza-xylo-cytidine is an analogue of purine nucleoside. | |
|
V80216 | 5-Caroxy uracil-1-yl acetic acid benzyl ester | 5-Caroxy uracil-1-yl acetic acid benzyl ester is an analogue of purine nucleoside. | |
|
V81071 | 5-Fluoro-3'-beta-C-methyluridine | 5-Fluoro-3'-beta-C-methyluridine is an analogue of purine nucleoside. | |
|
V77652 | 5-Fluoro-4'-thio-cytidine | 5-Fluoro-4'-thio-cytidine is an analogue of purine nucleoside. | |
|
V77661 | 5-Methoxy-4'-thiouridine | 5-Methoxy-4'-thiouridine is an analogue of purine nucleoside. | |
|
V80312 | 5-Methoxy-5'(R)-C-methyluridine | 5-Methoxy-5'(R)-C-methyluridine is a uridine analog. | |
|
V77665 | 5-N-(t-Butyloxycarbonylmethyl)-N-trifluoro acetyl-aminomethyl-2'-O-methyluridine | 5-N-(t-Butyloxycarbonylmethyl)-N-trifluoro acetyl-aminomethyl-2'-O-methyluridine is an analogue of purine nucleoside. | |
|
V80171 | 6-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine | 6-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is an analogue of purine nucleoside. |
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