New7

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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New7

New7 related products

Cat No.	Product Name	CAS No.	Product Description
V4980	PI3Kγ inhibitor 2	1315538-79-4	PI3Kγ inhibitor 2 (Compound 16 in referenceJ Med Chem.
V4992	PI3kδ inhibitor 1	1332075-63-4	PI3kδ inhibitor 1 is a novel, potent and selectivePI3Kδinhibitor with anIC50of 3.8 nM.
V4969	PI3Kδ-IN-1	1911564-39-0	PI3Kδ-IN-1 is a novel, potent, selective, and efficacious PI3Kδ inhibitor with an IC50of 1.7 nM.
V4987	PI4KIII beta inhibitor 3	1245319-54-3	PI4KIII beta inhibitor 3, extracted fromWO 2013034738 A1, is a novel and potent PI4KIIIβ inhibitor with IC50of 5.7 nM.
V4756	PQR-530	1927857-61-1	PQR-530 is a novel, potent, orally bioavailable and brain-penetrant dual pan-PI3K/mTORC1/2inhibitor, it exhibits antitumor activity.
V4984	PR-104	851627-62-8	PR-104, a novel, potent, non-toxic, small-molecule, hypoxia-activated, 3,5-dinitrobenzamide nitrogen mustard, is a drug from the class of hypoxia-activated prodrugs (HAPs), which is being researched as a potential anti-cancer therapeutic agent.
V4535	PROTAC ABL binding moiety 2	778277-37-5	PROTAC ABL binding moiety 2 is the GNF5 (an ABL inhibitor) moiety that binds to IAP (inhibitor of apoptosis protein) ligand via a linker to form SNIPER.
V4742	PROTAC BET Degrader-3		PROTAC BET Degrader-3 is a PROTAC protein degrader linked by von Hippel-Lindau ligand and BET ligand.
V4744	PROTAC-PEG3-Amino	189808-70-6	NH2-PEG3-C1-Boc (PROTAC (PROteolysis TArgeting Chimera) linker 5) is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category.
V4745	PROTAC-PEG3-Benene sulfonyl	1246999-33-6	Tos-PEG4-NH-Boc (PROTAC (PROteolysis TArgeting Chimera) linker 7) is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category.
V4954	PRX933 HCl	639029-42-8	PRX933 HCl, the hydrochloride salt form of PRX933 which is extracted from patent WO 2014140631 A1, is a novel and potent 5-HT2creceptor agonist
V4687	PTC299	1256565-36-2	PTC-299 (PTC299; PTC 299) is a novel, potent and orally bioavailableVEGFinhibitorwith potential antiangiogenesis and antineoplastic activities.
V5164	Rimeporid (EMD 87580)	187870-78-6	Rimeporide (also known as EMD-87580) is a novel, potent and selective inhibitor of the sodium/hydrogen Na+/H+exchanger (NHE-1) with a potential to be used as a therapeutic agent for the treatment of heart failure and for patients with Duchenne muscular dystrophy.
V4624	S-8510	151224-83-8	S-8510 (SB-737552) is a novel and potent partial inverseBenzodiazepine (BDZ) receptoragonist, with Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively.
V4736	San78-130	66018-45-9	San78-130 is a novel, potent and selectiveALK1inhibitor with anIC50of 62 nM.
V4606	SB 258719	195199-95-2	SB 258719 (SB-258719) is a novel, potent and selective5-HT7receptorantagonist with apKiof 7.5.
V4616	SB-423562	351490-72-7	SB-423562 is a novel and potent short-acting calcium-sensing receptor(CaR)antagonist.
V4619	SB-568849	395679-53-5	SB-568849 is a novel and potent melanin-concentrating hormone receptor 1(MCH R1) antagonist with apKiof 7.7.
V4621	SB-616234A	908601-49-0	SB-616234A is a novel, potent, selective and orally bioavailable5-HT1B receptorantagonist, with anxiolytic and antidepressant activity.
V4620	SB-7720770 2HCl	607373-46-6	SB-772077B dihydrochloride (also known as SB-772077-B; SB-772077) is a novel and potent aminofurazan-basedRho kinase( ROCK)inhibitor withIC50s of 5.6 nM and 6 nM toward ROCK1 and ROCK2, respevtively.