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Structure Cat No. Product Name CAS No. Product Description
V5280 24, 25-Dihydroxy Vitamin D3 40013-87-4 24, 25-Dihydroxy Vitamin D3 (24, 25-Dihydroxy D3; 24, 25-Dihydroxy VD3) is a vitamin D3 analog with important biological activities (anticancer, antiinflammatory et al.
V4404 ABT-670 630119-43-6 ABT-670 is a novel, potent, selective, orally bioavailable agonist ofdopamine D4receptorwithEC50of 89 nM, 160 nM, and 93 nM for human D4, ferret D4, and rat D4, respectively.
V5251 Apraclonidine HCl (iopidine) 73218-79-8 Apraclonidine (iopidine) HCl, the hydrochloride salt of Apraclonidine, is a potent sympathomimetic acting as an alpha2-adrenergic agonist and is used in glaucoma therapy.
V4701 BI-689648 1633009-87-6 BI 689648 is a novel, potent and highly selectivealdosterone synthase (AS)inhibitor that can attenuate the production of aldosterone directly and has been proposed as an alternative to mineralocorticoid receptor antagonists for blocking the pathologic effects of excess aldosterone.
V4498 BMS 433771 543700-68-1 BMS 433771 is a novel and potent inhibitor of RSV (respiratory syncytial virus) replication in vitro.
V5218 Carboprost tromethamine 58551-69-2 Carboprost (Hemabate, Tham) is a synthetic prostaglandin analogue of PGF2α (specifically, it is 15-methyl-PGF2α) with oxytocic properties.
V5229 CDD3505 173865-33-3 CDD3505 is a novel HDL cholesterol level inducing compound used for elevating high density lipoprotein cholesterol (HDL) by inducing hepaticcytochrome P450IIIA (CYP3A)activity.
V4490 CE-224535 724424-43-5 CE-224535 is anovel and selective P2X7 receptor antagonist that can be potentially used for the treatment of rheumatoid arthritis and osteoarthritis.
V4439 cFMS Receptor Inhibitor III 959861-21-3 cFMS Receptor Inhibitor III is a novel, potent and cell-permeable anilinoquinoline compound that acts as a strong, active site-targeting inhibitor of M-CSF/c-Fms-CSF-1R (MCSF receptor/cFMS) with IC50of 8 nM.
V5278 Cortistatin-14 (CST-14) 193829-96-8 Cortistatin-14 (CST-14), a recently discovered cyclic neuropeptide with neuronal depressant and sleep modulating properties, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological activities and co-exists with GABA within the cortex and hippocampus.
V5269 CP 375 752186-89-3 CP 375 is a novel and potent Fe3+chelating agent with a log K1value of 14.50 and with the absolute deviation between the predicted and experimental values of 0.12 (14.62 vs.
V5273 CP-10 2366268-80-4 CP-10 (CP10; CP 10), designed from a focused PROTAC library hijacking cancer therapeutic target CDK6, is a novel and potent PROTAC-based protein degrader targeting CDK6 with high selectivity, specificity, and remarkable CDK6 degradation efficiency (DC50=2.1 nM).
V5271 CP-28888 (CP 28888-27) 69938-75-6 CP-28888 (CP-28,888-27) is a novel and potent interferon inducer, it is more potent in mice, but is less active in man and devoid of antirhinovirus effects.
V5270 CP-316311 175139-41-0 CP 316311 is a novel, potent, selective and orally bioactive antagonist of the corticotropin-releasing factor 1 (CRF 1) receptor with anIC50value of 6.8 nM.
V5207 CP-409092 HCl 225240-86-8 CP-409092 HCl, the hydrochloride salt ofCP-409092, is a novel and potent partial agonist ofGABAAreceptorwith potential anti-anxiety activity.
V5299 CP-96486 139401-45-9 CP-96486 is a novel, potent and orally bioavailable antagonist of leukotriene D4(LTD4)/platelet activating factor (PAF) receptor withKis of 20 and 24 nM, respectively.
V4491 Dagrocorat 1044535-52-5 Dagrocorat (also known as PF-00251802) is a novel and potentdissociated glucocorticoid receptoragonist with thepotential usefulness as an anti-inflammatory agent.
V5327 Deacetoxycephalosporin C 26924-74-3 Deacetoxycephalosporin C (also known as DAOC),a cephalosporin derived from a cephalosporin C, is a novel and potentcephalosporin antibiotic and a precursor of cephalosporins excreted by Cephalosporium and Streptomyces species.
V5260 Dolcanatide (SP-333) 1092457-65-2 Dolcanatide(formerly SP-333; SP333; SP 333) is the second uroguanylin analog currently being developed for ulcerative colitis by Synergy Pharmaceuticals which is a biopharmaceutical company focused on the development and commercialization of novel gastrointestinal (GI) therapies.
V5265 DPQ 129075-73-6 DPQ (also known as PARP Inhibitor III) is a novel and potent inhibitor of PARPs [The poly(ADP-ribose) polymerases] which inhibits PARP1 activity with an IC50value of 40 nM.
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