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V5280
|
24, 25-Dihydroxy Vitamin D3 |
40013-87-4 |
24, 25-Dihydroxy Vitamin D3 (24, 25-Dihydroxy D3; 24, 25-Dihydroxy VD3) is a vitamin D3 analog with important biological activities (anticancer, antiinflammatory et al. |
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V4404
|
ABT-670 |
630119-43-6 |
ABT-670 is a novel, potent, selective, orally bioavailable agonist ofdopamine D4receptorwithEC50of 89 nM, 160 nM, and 93 nM for human D4, ferret D4, and rat D4, respectively. |
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V5251
|
Apraclonidine HCl (iopidine) |
73218-79-8 |
Apraclonidine (iopidine) HCl, the hydrochloride salt of Apraclonidine, is a potent sympathomimetic acting as an alpha2-adrenergic agonist and is used in glaucoma therapy. |
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V4701
|
BI-689648 |
1633009-87-6 |
BI 689648 is a novel, potent and highly selectivealdosterone synthase (AS)inhibitor that can attenuate the production of aldosterone directly and has been proposed as an alternative to mineralocorticoid receptor antagonists for blocking the pathologic effects of excess aldosterone. |
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V4498
|
BMS 433771 |
543700-68-1 |
BMS 433771 is a novel and potent inhibitor of RSV (respiratory syncytial virus) replication in vitro. |
|
V5218
|
Carboprost tromethamine |
58551-69-2 |
Carboprost (Hemabate, Tham) is a synthetic prostaglandin analogue of PGF2α (specifically, it is 15-methyl-PGF2α) with oxytocic properties. |
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V5229
|
CDD3505 |
173865-33-3 |
CDD3505 is a novel HDL cholesterol level inducing compound used for elevating high density lipoprotein cholesterol (HDL) by inducing hepaticcytochrome P450IIIA (CYP3A)activity. |
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V4490
|
CE-224535 |
724424-43-5 |
CE-224535 is anovel and selective P2X7 receptor antagonist that can be potentially used for the treatment of rheumatoid arthritis and osteoarthritis. |
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V4439
|
cFMS Receptor Inhibitor III |
959861-21-3 |
cFMS Receptor Inhibitor III is a novel, potent and cell-permeable anilinoquinoline compound that acts as a strong, active site-targeting inhibitor of M-CSF/c-Fms-CSF-1R (MCSF receptor/cFMS) with IC50of 8 nM. |
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V5278
|
Cortistatin-14 (CST-14) |
193829-96-8 |
Cortistatin-14 (CST-14), a recently discovered cyclic neuropeptide with neuronal depressant and sleep modulating properties, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological activities and co-exists with GABA within the cortex and hippocampus. |
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V5269
|
CP 375 |
752186-89-3 |
CP 375 is a novel and potent Fe3+chelating agent with a log K1value of 14.50 and with the absolute deviation between the predicted and experimental values of 0.12 (14.62 vs. |
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V5273
|
CP-10 |
2366268-80-4 |
CP-10 (CP10; CP 10), designed from a focused PROTAC library hijacking cancer therapeutic target CDK6, is a novel and potent PROTAC-based protein degrader targeting CDK6 with high selectivity, specificity, and remarkable CDK6 degradation efficiency (DC50=2.1 nM). |
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V5271
|
CP-28888 (CP 28888-27) |
69938-75-6 |
CP-28888 (CP-28,888-27) is a novel and potent interferon inducer, it is more potent in mice, but is less active in man and devoid of antirhinovirus effects. |
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V5270
|
CP-316311 |
175139-41-0 |
CP 316311 is a novel, potent, selective and orally bioactive antagonist of the corticotropin-releasing factor 1 (CRF 1) receptor with anIC50value of 6.8 nM. |
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V5207
|
CP-409092 HCl |
225240-86-8 |
CP-409092 HCl, the hydrochloride salt ofCP-409092, is a novel and potent partial agonist ofGABAAreceptorwith potential anti-anxiety activity. |
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V5299
|
CP-96486 |
139401-45-9 |
CP-96486 is a novel, potent and orally bioavailable antagonist of leukotriene D4(LTD4)/platelet activating factor (PAF) receptor withKis of 20 and 24 nM, respectively. |
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V4491
|
Dagrocorat |
1044535-52-5 |
Dagrocorat (also known as PF-00251802) is a novel and potentdissociated glucocorticoid receptoragonist with thepotential usefulness as an anti-inflammatory agent. |
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V5327
|
Deacetoxycephalosporin C |
26924-74-3 |
Deacetoxycephalosporin C (also known as DAOC),a cephalosporin derived from a cephalosporin C, is a novel and potentcephalosporin antibiotic and a precursor of cephalosporins excreted by Cephalosporium and Streptomyces species. |
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V5260
|
Dolcanatide (SP-333) |
1092457-65-2 |
Dolcanatide(formerly SP-333; SP333; SP 333) is the second uroguanylin analog currently being developed for ulcerative colitis by Synergy Pharmaceuticals which is a biopharmaceutical company focused on the development and commercialization of novel gastrointestinal (GI) therapies. |
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V5265
|
DPQ |
129075-73-6 |
DPQ (also known as PARP Inhibitor III) is a novel and potent inhibitor of PARPs [The poly(ADP-ribose) polymerases] which inhibits PARP1 activity with an IC50value of 40 nM. |