|
V5208
|
PI3Kδ inhibitor 2 |
2088525-31-7 |
PI3Kδ inhibitor 2 is a novel, highly potent and selective PI3Kδ inhibitor with IC50 of 0.9 nM in the enzyme assay, and 20-120nM of cell potency in a JeKo-cell assay. |
|
V5304
|
Pristinamycin (NSC-246121) |
11006-76-1 |
Pristinamycin (Virginiamycin antibiotic complex; NSC-246121; Antibiotic 899; Founderguard) is a novel,naurally occuring streptogramin-like and potent antibiotic used primarily in the treatment of staphylococcal infections, and to a lesser extent streptococcal infections. |
|
V5305
|
Pristinamycin IA (Mikamycin B; Mikamycin IA) |
3131-03-1 |
Pristinamycin IA (also known as Mikamycin B; Mikamycin IA), a naturally occuring and biologically active decapeptide isolated from the skin of the Australian frogHyla caerulea, is a novel and potent cholecystokinetic agent which acts as a cholecystokinin receptor agonist. |
|
V4493
|
Sarolaner |
1398609-39-6 |
Sarolaner (also known as PF-6450567; PF6450567) is a novel, potent, orally bioactive and broad-spectrum ectoparasiticide (an antiparasitic agent for veterinary use). |
|
V5204
|
Seco Rapamycin sodium (Secorapamycin A monosodium) |
148554-65-8 |
Seco Rapamycin sodium (Secorapamycin A monosodium), the sodium salt of the ring-opened product of Rapamycin, is reported not to affect the mTOR function. |
|
V5250
|
SF-2312 |
107729-45-3 |
SF2312 is a novel, highly potent and low-nanomolar inhibitor of enolase. |
|
V5261
|
Sinogliatin (HMS-5552; RO-5305552) |
1191996-10-7 |
Sinogliatin (formerly HMS-5552; RO-5305552) is a a first-in-class glucokinase activator with the potential for the treatment of type 2 diabetes. |
|
V5013
|
THZ1-R |
1621523-07-6 |
THZ1-R is a novel and non-cysteine reactive analog of THZ1 which shows lower activity for CDK7 inhibition with a Kdof 142 nM for binding to CDK7. |
|
V5201
|
UNC4976 |
|
UNC4976 is a significantly improved cellularly efficacious chemical probe of CBX7. |
|
V5291
|
Zilpaterol hydrochloride |
119520-06-8 |
Zilpaterol, the hydrochloride salt of Zilpatero, is a novel and potent β-adrenergic receptor (AR) agonist used to increase the size of cattle and the efficiency of feeding them. |
|
V5311
|
Ziresovir (AK0529;RO-0529) |
1422500-60-4 |
Ziresovir (known also as AK-0529; RO-0529) is a selective and orally bioavailable inhibitor of respiratory syncytial virus (RSV) fusion (F) protein (RSV F) protein with EC50of 3 nM. |