Endogenous Metabolite

Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD
GPCR & G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase Adrenergic Receptor Angiotensin Receptor APJ Bombesin Receptor Bradykinin Receptor cAMP Cannabinoid Receptor CaSR CCK receptor CCR CGRP Receptor CRFR CXCR Dopamine Receptor EBI2 Endothelin Receptor Formyl Peptide Receptor Free Fatty Acid Receptor G protein-coupled Bile Acid Receptor GCGR GHSR GLP Receptor Glucagon Receptor GnRH Receptor GPCR19 GPR GPR109A Guanylate Cyclase Hedgehog(Smoothened) ROCK Histamine Receptor ICMT Leukotriene Receptor LPA Receptor LPL Receptor LTR mAChR Melanocortin Receptor Melatonin Receptor mGluR Motilin Receptor MRGPR MT Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor NPY receptor Opioid Receptor OX Receptor Oxytocin Receptor P2Y Receptor PAFR PAR PKD PKG Prostaglandin Receptor Ras RGS Protein S1P Receptor SGLT Sigma Receptor Somatostatin Receptor TAAR TSH Receptor Urotensin Receptor Vasopressin Receptor

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Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. Endogenous variables like age, sex, body composition, genetics, and underlying pathologies have an impact on a given body fluid's metabolome. The activity of an enormous variety of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules typically keeps the levels of the enormous variety of unique small-molecule metabolites tightly regulated. In the brain, endogenous small molecules are typically present at levels that are tightly controlled.

Endogenous Metabolite related products

Cat No.	Product Name	CAS No.	Product Description
V55722	15-keto-Prostaglandin E2 (15-keto-PGE2)	26441-05-4	15-keto-Prostaglandin E2 is an endogenously produced metabolite.
V80016	16α-Hydroxydehydroepiandrosterone-d5		16α-Hydroxydehydroepiandrosterone-d5 is the deuterium labelled form of 16α-Hydroxydehydroepiandrosterone.
V72346	16α-Hydroxyestrone (16αOHE)	566-76-7	16α-Hydroxyestrone (16αOHE) is the major metabolite of estradiol.
V72546	17a-Hydroxypregnenolone-d3	105078-92-0	17a-Hydroxypregnenolone-d3 is the deuterium labelled form of 17a-Hydroxypregnenolone.
V71047	18:0,18:1 PS sodium	321883-23-2	18:0,18:1 PS sodium is a lipid component of synaptic vesicles and cholesterol and may be utilized in metabolic studies.
V82029	18:0,22:6 PS sodium	474943-18-5	18:0,22:6 PS sodium is a lipid component of synaptic vesicles and cholesterol and may be utilized in metabolic studies.
V71108	19-Hydroxyandrost-4-ene-3,17-dione	510-64-5	19-Hydroxyandrost-4-ene-3,17-dione is a substrate of adrenocorticotropic hormone-lipotropin and cytochrome P450 19A1.
V72337	1H-pyrazole	288-13-1	1H-pyrazole is an endogenously produced metabolite.
V72301	2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium)	2734858-36-5	2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is an endogenous cGAMP in mammalian cells.
V72569	2′-Deoxyadenosine 5′-monophosphate disodium (2′-deoxyadenosine-5′-monophosphate disodium)	2922-74-9	2′-Deoxyadenosine 5′-monophosphate disodium is a nucleic acid AMP analogue, a deoxyribonucleotide present in DNA.
V77558	2′-Deoxyadenosine 5′-monophosphate-13C10,15N5 disodium (2′-Deoxyadenosine-5′-monophosphate-13C10,15N5)		2′-Deoxyadenosine 5′-monophosphate-13C10,15N5 (disodium) is 13C (carbon 13) and 15N (nitrogen 15) labelled 2′-Deoxyadenosine 5′-monophosphate disodium.
V70892	2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate	2483830-27-7	2'-Deoxyadenosine monohydrate-13C10,15N5 (hydrate) is 13C and 15N labeled 2'-Deoxyadenosine monohydrate.
V80421	2'-Deoxyadenosine monohydrate-15N5		2'-Deoxyadenosine monohydrate-15N5 is a 15N-labeled 2'-Deoxyadenosine monohydrate.
V80509	2'-Deoxyadenosine-13C10		2'-Deoxyadenosine-13C10 is a 13C (carbon 13)-labeled 2'-Deoxyadenosine.
V82196	2'-Deoxyadenosine-5'-monophosphate	653-63-4	2′-Deoxyadenosine 5′-monophosphate is a nucleic acid AMP analogue, a deoxyribonucleotide present in DNA.
V80512	2'-Deoxyadenosine-5'-monophosphate-13C10 dilithium		2'-Deoxyadenosine-5'-monophosphate-13C10 dilithium is 13C (carbon 13) labelled 2'-Deoxyadenosine-5'-monophosphate.
V82007	2'-Deoxyadenosine-5'-monophosphate-13C10,15N5 dilithium	2483830-51-7	2'-Deoxyadenosine-5'-monophosphate-13C10,15N5 dilithium is 13C (carbon 13) and 15N (nitrogen 15) labelled 2'-Deoxyadenosine-5'-monophosphate.
V77575	2'-Deoxyadenosine-5'-monophosphate-15N5 dilithium		2'-Deoxyadenosine-5'-monophosphate-15N5 dilithium is 15N (nitrogen 15) labelled 2'-Deoxyadenosine-5'-monophosphate.
V77576	2'-Deoxyadenosine-5'-monophosphate-15N5,d12 dilithium		2'-Deoxyadenosine-5'-monophosphate-15N5,d12 dilithium is a deuterated and 15N (nitrogen 15) labelled 2'-Deoxyadenosine-5'-monophosphate.
V77577	2'-Deoxyadenosine-5'-monophosphate-d12 dilithium		2'-Deoxyadenosine-5'-monophosphate-d12 dilithium is deuterium labelled 2'-Deoxyadenosine-5'-monophosphate.