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    JNJ-632
    JNJ-632

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    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V4501
    CAS #: 1572510-42-9Purity ≥98%

    Description: JNJ-632 is a novel and potent hepatitis B virus (HBV) capsid assembly modulator (CAM). Small molecule induced hepatitis B virus (HBV) capsid assembly modulation is considered an attractive approach for new antiviral therapies against HBV. JNJ-632 has been used as a tool compound to further profile the mode of action. Administration of JNJ-632 (54) in HBV genotype D infected chimeric mice resulted in a 2.77 log reduction of the HBV DNA viral load.

    References:  2018 Jul 26;61(14):6247-6260. 


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    JNJ-632Name: JNJ-632
    CAS#: 1572510-42-9
    Chemical Formula: C18H19FN2O4S
    Exact Mass: 378.105
    Molecular Weight: 378.4184
    Elemental Analysis: C, 57.13; H, 5.06; F, 5.02; N, 7.40; O, 16.91; S, 8.47
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Technical InformationSynonym: JNJ-632; JNJ 632; JNJ632.
    IUPAC/Chemical Name: (S)-N-(4-fluoro-3-methylphenyl)-3-(N-(tetrahydrofuran-3-yl)sulfamoyl)benzamide
    InChi Key: JIZGLOVJKCSHTH-HNNXBMFYSA-N
    InChi Code: InChI=1S/C18H19FN2O4S/c1-12-9-14(5-6-17(12)19)20-18(22)13-3-2-4-16(10-13)26(23,24)21-15-7-8-25-11-15/h2-6,9-10,15,21H,7-8,11H2,1H3,(H,20,22)/t15-/m0/s1
    SMILES Code: O=C(NC1=CC=C(F)C(C)=C1)C2=CC=CC(S(=O)(N[[email protected]@H]3COCC3)=O)=C2


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