A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V76273 | α-Phellandrene (alpha-Phellandrene) | 99-83-2 | Alpha-Phellandrene (alpha-Phellandrene) has antifungal activity. |
|
V76261 | α-Terpinene (α-Terpinene; Terpilene) | 99-86-5 | α-Terpinene (Terpilene) is a monoterpene found in many foods and in the essential oils of aromatic plants such as Mentha piperita. |
|
V76264 | β-Tomatine | 17406-46-1 | β-Tomatine is a degradation product of α-tomatine and is a less fungal-toxic compound. |
|
V6552 | Amphotericin B | 1397-89-3 | Amphotericin B (Fungizone; Amfocan; Ambisome;NSC527017;Amphozone; Fungilin; Amfocare; Amfotex; Amfotex) is a naturally occurringpolyene antifungal agent approved for treating serious fungal infections and leishmaniasis, such as mucormycosis, coccidioidomycosis,candidiasis,aspergillosis, blastomycosis, and cryptococcosis. |
|
V29225 | Acetyllovastatin | 81189-92-6 | Acetyllovastatin is the acetated form of Lovastatinacetate of Lovastatin, which is a statin drug for hyperlipidemia. |
|
V29621 | Dihydrochelerythrine | 6880-91-7 | Dihydrochelerythrine is a bioactive natural product extracted from Corydalis yanhusuo andthe leaves of Macleaya microcarpawith antifungal activity. |
|
V25006 | Mancozeb | 8018-01-7 | Mancozeb is an ethylene bisdithiocarbamate fungicide. |
|
V2352 | Liranaftate (Piritetrate; M-732) | 88678-31-3 | Liranaftate (formerly M-732; Piritetrate; Zefnart) is a thiocarbamate-based inhibitor of squalene epoxidase with fungicidal activities. |
|
V32994 | Nystatin | 1400-61-9 | Nystatin (Candex;Mycostatin;Barstatin 100; Biofanal;AI3-26526) is a potent polyeneantifungal antibiotic with abroad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notablyCandidaspecies. |
|
V1965 | Luliconazole (NND 502) | 187164-19-8 | Luliconazole (also known as NND-502;NND502; Luzu) is an imidazole-based antifungaldrug that is usedfor the topical treatment of interdigital tinea pedis. |
|
V2088 | Amorolfine HCl (Ro 14-4767/002) | 78613-38-4 | Amorolfine HCl (Ro 14-4767/002), a topically administered drug, is a potent and broad-spectrum antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts. |
|
V34239 | Purpurin | 81-54-9 | Purpurin is a natural anthraquinone compound from Rubia cordifolia L. |
|
V27269 | Penthiopyrad | 183675-82-3 | Penthiopyrad (MTF-753) is a chiral carboxamide antifungal compound/agent with broad spectrum (a wide range) bactericidal ( bacteria killing) activity. |
|
V24011 | Levoketoconazole [(-)-Ketoconazol; (-)-R 41400] | 142128-57-2 | Levoketoconazole [(-)-Ketoconazole ((-)-R 41400)],the levo-enantiomer of Ketoconazole, is useful for treatment of Cushing's Syndrome. |
|
V5560 | Basifungin | 127785-64-2 | Aureobasidin A (Basifungin) is a cyclic peptide and antifungal antibiotic. |
|
V30312 | Isoschaftoside | 52012-29-0 | Isoschaftosid is a c-glycosyl flavonoid found in the root exudate of Desmodium uncinatum, which can inhibit the growth of S. |
|
V17438 | Iprobenfos | 26087-47-8 | Iprobenfos is a potent organophosphorus pesticide and fungicide widely used to control the rice blast fungus. |
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V4160 | Coniferyl alcohol | 458-35-5 | Coniferyl alcohol is an important intermediate used in biosynthesis of eugenol and of stilbene and coumarin. |
|
V7370 | Flusilazole | 85509-19-9 | Flusilazole (Olymp;DPX-6573;Sanction;Flusilazole; DPX6573;Flusilazol;DPX 6573;Nustar) is a potent organosilicon fungicide that has beenused for the control of fungal infections on a variety of vegetable and fruit crops. |
|
V21174 | Fluxapyroxad | 907204-31-3 | Fluxapyroxad is a novel, broad-spectrumand potent fungicidal agent acting as asuccinate dehydrogenase inhibitor (SDHI). |
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