| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V70620 | Desmethyl-YM-298198 hydrochloride | 1177767-57-5 | Desmethyl-YM-298198 HCl is a high-affinity, selective, noncompetitive mGluR1 antagonist (IC50= 16 nM). |
|
V70626 | DMeOB (3,3'-Dimethoxybenzaldazine) | 40252-74-2 | DMeOB is an agonist of mGluR5 receptor with IC50 of 3 μM. |
|
V4895 | Eglumegad | 176199-48-7 | Eglumegad (also known as LY-354740) is a novel, highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively. |
|
V77047 | Eglumegad hydrochloride (LY354740 hydrochloride; Eglumetad hydrochloride) | Eglumegad (LY354740) HCl is a potent and specific group II (mGlu2/3) receptor agonist/activator with IC50 of 5 and 24 nM for human mGlu2 and mGlu3 receptors, respectively. | |
|
V21041 | FITM | 932737-65-0 | FITM is a negative allosteric modulator (NAM) of the mGlu1 receptor with Ki of 2.5 nM. |
|
V3325 | FPTQ | 864863-72-9 | FPTQ is novel and potent antagonist of mGluR1 (metabotropic glutamate receptor subtype 1) with IC50 of 6 nM and 1.4 nM for human and mouse mGluR1 respectively. |
|
V3356 | FTIDC | 873551-53-2 | FTIDC is a novel, orally bioactive, highly potent and selective negative allosteric modulator/antagonist of metabotropic glutamate receptor (mGluR) 1 with anxiolytic and antipsychotic effects. |
|
V50980 | HexylHIBO | 334887-43-3 | HexylHIBO is a type I mGluR antagonist (inhibitor) with Kb values of 140 and 110 μM at mGlu1a and mGlu5a receptors. |
|
V70625 | IEM-1925 bromide | 258282-23-4 | IEM-1925 bromide is an orally bioactive glutamate receptor antagonist that increases latency and reduces ongoing symptoms such as epilepsy in rat models. |
|
V70612 | JF-NP-26 | 2341841-03-8 | JF-NP-26 is an inactive photocaged analogue of Raseglurant and the first NAM (negative allosteric modulator) of photocaged mGlu5 receptors. |
|
V3326 | JNJ-16259685 | 409345-29-5 | JNJ16259685 (JNJ-16259685) is a novel, potent, selective and non-competitive antagonist of mGlu1 receptor with IC50 of 19 nM. |
|
V2921 | JNJ-40411813 | 1127498-03-6 | JNJ-40411813 (formerly known as ADX71149) is a novel positive allosteric modulator of the mGlu2R receptor (metabotropic Glutamate 2 receptor) with EC50 of 147 nM. |
|
V2844 | JNJ-42153605 | 1254977-87-1 | JNJ-42153605 is a potent, selective and allosteric modulator of the mGlu2 (metabotropic glutamate 2) receptor with with an EC50 of 17 nM. |
|
V4511 | JNJ-46778212 | 1363281-27-9 | JNJ-46778212 (also known as VU 0409551) is a novel, potent,orally bioavailable metabotropic glutamate receptor subtype 5 (mGlu5)positive allosteric modulator (PAMs) with anEC50of 260 nM. |
|
V50939 | L-AP3 | 23052-80-4 | L-AP3, a metabotropic glutamate receptor (mGluR) antagonist, inhibits D-phosphoserine and L-phosphoserine with IC50s of 368 μM and 2087 μM, respectively. |
|
V70608 | L-AP4 monohydrate (L-APB monohydrate) | 2247534-79-6 | L-AP4 (L-APB) monohydrate is a potent, specific agonist of metabotropic glutamate receptors (mGluR) with EC50s of 0.13, 0.29 for mGlu4, mGlu8, mGlu6 and mGlu7 receptors respectively. |
|
V70603 | L-CCG-I | 117857-93-9 | L-CCG-I is an expanded isomer of a conformationally restricted glutamate analogue. |
|
V16769 | LSN2463359 | 1401031-52-4 | LSN-2463359 is a novel and potent PAM/positive allosteric modulator of metabotropic glutamate 5 (mGlu5). |
|
V4655 | Lu AF21934 | 1445605-23-1 | Lu AF21934 is a novel, potent, selective and brain-penetrant positive allosteric modulator of mGlu4 receptors with an IC50 of 500 nM for human mGlu4 |
|
V24476 | Lu AF32615 | 125404-04-8 | TCN238 is an orally bioavailable positive allosteric modulator (PAM) of the mGlu4 receptor with EC50 of 1 μM. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
