Microtubules are a component of the cytoskeleton, found throughout the cytoplasm.These highly dynamic tubular tubulin polymers have an average length of 25 m and a maximum growth length of 50 micrometers. A microtubule has an inner diameter of 12 nm and an outer diameter of about 24 nm. Alpha and beta tubulin combine to form a dimer, which is then polymerized to form microtubules, which are found in eukaryotic cells. One of many members of a small family of globular proteins is tubulin.The alpha-, beta-, gamma-, delta-, and epsilon-tubulins are among the five distinct families that make up the tubulin superfamily, and a sixth family is only found in kinetoplastid protozoa. The proteins that make up microtubules, -tubulin and -tubulin, are the most prevalent members of the tubulin family. Microtubules play a crucial role in many cellular processes. They assist in keeping the cell's structure intact.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V7586 | Taltobulin | 228266-40-8 | Taltobulin (HTI-286; SPA-110), an analog of the natural tripeptide hemiasterlin, is a tubulin inhibitor with anticancer activity. |
|
V76455 | Taltobulin hydrochloride (HTI-286 hydrochloride; SPA-110 hydrochloride) | Taltobulin HCl (HTI-286 HCl) is a synthetic tripeptide cysteine analogue. | |
|
V31385 | Taltobulin trifluoroacetate | 228266-41-9 | Taltobulin trifluoroacetate (HTI-286; HTI286; SPA-110; SPA110), the trifluoroacetate salt of taltobulin, is an nalogue of Hemiasterlin, acting as a tubulin inhibitor and used as an ADC cytotoxin (warhead). |
|
V35220 | Tau tracer 1 | 2173353-53-0 | Tau tracer 1 is a Tau tracer used for imaging Tau protein aggregates. |
|
V35219 | Tau tracer 2 (Pl-2620) | 2173361-80-1 | Tau tracer 2 (Pl-2620) is a Tau tracer used for imaging Tau protein aggregates. |
|
V55255 | Taxinine B (Taxinin B) | 18457-44-8 | Taxinine B is a taxane extracted from the Japanese yew Taxus Cuspid. |
|
V55249 | Tilavonemab (ABBV-8E12; C2N-8E12) | 2096513-89-0 | Tilavonemab (ABBV-8E12) is a humanized anti-tau antibody that binds to amino acid (AA)s 25-30 near the N-terminus of the tau protein. |
|
V16531 | TN-16 | 33016-12-5 | TN-16 (TN16; NSC-239274) is a potent tubulin inhibitor (antitubulin/antimitotic agent) with anticancer activity. |
|
V75822 | Tubulin inhibitor 15 | 2767446-36-4 | Tubulin inhibitor 15 is a potent tubulin inhibitor. |
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V75820 | Tubulin inhibitor 16 | 2767446-32-0 | Tubulin inhibitor 16 is a potent tubulin inhibitor. |
|
V79473 | Tubulin inhibitor 31 | Tubulin inhibitor 31 is a potent tubulin inhibitor (antagonist) with IC50 of 4 µM. | |
|
V79656 | Tubulin inhibitor 34 | Tubulin inhibitor 34 (compound b5) is an effective anticancer agent. | |
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V80143 | Tubulin inhibitor 36 | Tubulin inhibitor 36 (Compound 10) is a new type of potent tubulin inhibitor that can inhibit tubulin polymerization and induce cell apoptosis. | |
|
V81644 | Tubulin inhibitor 37 | Tubulin inhibitor 37 (compound 12) is a Tubulin inhibitor that can effectively inhibit Tubulin polymerization (IC50=1.3 µM). | |
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V81645 | Tubulin inhibitor 38 | Tubulin inhibitor 38 (compound 14) is a tetrazolium-based tubulin (Microtubule/Tubulin) inhibitor (antagonist) with antiproliferation ability. | |
|
V39080 | Tubulin inhibitor 6 | 105925-39-1 | Tubulin inhibitor 6 (Compound 14b) is a novel and potent tubulin inhibitor (mitotic inhibitor or tubulin destabilizer) with anticancer activity. |
|
V51291 | Tubulin polymerization-IN-11 | 2470063-59-1 | Tubulin polymerization-IN-11 is a novel and selective inhibitor of tubulin polymerization with an IC50 value of 3.4 µM. |
|
V34711 | Tubulin polymerization-IN-12 | 2377301-45-4 | Tubulin polymerization-IN-12 is an inhibitor (blocker/antagonist) of tubulin polymerization (IC50=0.75 μM). |
|
V75812 | Tubulin polymerization-IN-2 | 2873399-22-3 | Tubulin polymerization-IN-2 is a potent anti-cancer active molecule targeting β-tubulin with IC50 of 0.92 μM. |
|
V78673 | Tubulin polymerization-IN-33 | Tubulin polymerization-IN-33 is an inhibitor (blocker/antagonist) of [1,2] oxazoloisoindole tubulin polymerization and has high anti-proliferation activity against NCI series cancer/tumor cells. |
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