NF-κB

Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD
GPCR & G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase Adrenergic Receptor Angiotensin Receptor APJ Bombesin Receptor Bradykinin Receptor cAMP Cannabinoid Receptor CaSR CCK receptor CCR CGRP Receptor CRFR CXCR Dopamine Receptor EBI2 Endothelin Receptor Formyl Peptide Receptor Free Fatty Acid Receptor G protein-coupled Bile Acid Receptor GCGR GHSR GLP Receptor Glucagon Receptor GnRH Receptor GPCR19 GPR GPR109A Guanylate Cyclase Hedgehog(Smoothened) ROCK Histamine Receptor ICMT Leukotriene Receptor LPA Receptor LPL Receptor LTR mAChR Melanocortin Receptor Melatonin Receptor mGluR Motilin Receptor MRGPR MT Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor NPY receptor Opioid Receptor OX Receptor Oxytocin Receptor P2Y Receptor PAFR PAR PKD PKG Prostaglandin Receptor Ras RGS Protein S1P Receptor SGLT Sigma Receptor Somatostatin Receptor TAAR TSH Receptor Urotensin Receptor Vasopressin Receptor

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NF-κB

Nuclear factor-κB (NF-κB)/Rel proteins include NF-κB2 p52/p100, NF-κB1 p50/p105, c-Rel, RelA/p65, and RelB.These proteins perform as two-component transcription factors that control gene expression and have an impact on a variety of biological processes, such as innate and acquired immunity, inflammation, stress responses, B-cell development, and lymphoid organogenesis.The immune system's reaction to infection is significantly regulated by NF-B. In addition, the etiology of chronic inflammatory illnesses such inflammatory bowel disease, rheumatoid arthritis, and asthma is influenced by the activation of the NF-B pathway. Septic shock, autoimmune and inflammatory disorders, viral infections, and poor immunological development have all been connected to faulty NF-B regulation.

NF-κB related products

Cat No.	Product Name	CAS No.	Product Description
V78014	Anti-inflammatory agent 50		Anti-inflammatory agent 50 (compound a1) is an analogue of Fusidic acid and has anti-inflammatory effects.
V79544	Anti-inflammatory agent 6		Anti-inflammatory agent 6 blocks the phosphorylation of Iκb kinase α/β (IKKα/β), IκBα and nuclear factor kB p65 (NF-κb p65), which are key controllers of inflammation, thereby showing anti-inflammatory potential.
V79083	Anti-inflammatory agent 66		Anti-inflammatory agent 66 (compound 8) is a pterostilbene analogue with anti-inflammatory activity.
V78020	Anti-inflammatory agent 7		anti~inflammatory agent 7 inhibits pro-inflammatory cytokines by blocking the NF-κB/MAPK signaling pathway in LPS-treated RAW 264.7 cells and mice.
V78049	Anti-osteoporosis agent-4		Anti-osteoporosis agent-4 (Compound 11h) inhibits the differentiation of primary osteoclasts.
V9472	Aristolochic acid A	313-67-7	Aristolochic acid A (Aristolochic acid I; TR 1736) is the major component of the plant extract Aristolochic acids, which is present in the herbs Aristolochia and Asarum.
V82267	Asperlactone	76375-62-7	Asperlactone exhibits anti-inflammatory effect.
V30086	Avicularin	572-30-5	Avicularin is a novel and potent flavonoid.
V82266	Banksialactone A	1135775-06-2	Banksialactone A is a metabolite of the Australian fungus Aspergillus bankianus.
V30080	Barlerin	57420-46-9	Barlerin (8-O-Acetyl shanzhiside methyl ester) is a cyclosporine glucoside extracted from a folk medicinal plant in Tibet, China.
V4192	Bay 65-1942 HCl	600734-06-3	Bay 65-1942 HCl is the hydrochloride salt of of BAY65-1942 which is a novel, potent and selective ATP-competitive inhibitor ofIKKβ.
V82269	Beauveriolide I	154491-55-1	Beauveriolide I is a metabolite of the entomopathogenic fungus Beauveria sp.
V30474	Berbamine	478-61-5	Berbamine is a naturally occuring isoquinoline alkaloidfound in traditional Chinese medicineBarberry with anti-tumor, immunomodulatory and cardiovascular effects.
V29939	Berbamine dihydrochloride	6078-17-7	Berbamine 2HCl is a naturally occuring isoquinoline alkaloid found in traditional Chinese medicine Barberry with anti-tumor, immunomodulatory and cardiovascular effects.
V82274	Bisphenol A-d16 (bisphenol A-d16)	96210-87-6	Bisphenol A-d16 is the deuterium labelled form of Bisphenol A.
V82273	Bisphenol A-d4-1 (bisphenol A-d4-1)	347841-41-2	Bisphenol A-d4-1 is the deuterated form of Bisphenol A.
V82272	Bisphenol A-d6 (bisphenol A d6)	86588-58-1	Bisphenol A-d6 is the deuterium labelled form of Bisphenol A.
V82276	Bisphenol A-d8 (bisphenol A-d8)	92739-58-7	Bisphenol A-d8 is a phenolic organic synthetic compound extensively used in the production of polycarbonate plastics and epoxy resins.
V17405	C25-140	1358099-18-9	C25-140 (C-25140;C25140) is a novel, first-in-class and potent inhibitor of RING-E3 ligase (TRAF6) / E2 enzyme (Ubc13) protein-protein interaction (PPI) with potential use forautoimmune and chronic inflammatory diseases.
V0766	Caffeic Acid Phenethyl Ester	104594-70-9	Caffeic acid phenethyl ester (also called CAPE; BAF-IN-C09; 2-Phenylethyl Caffeate; β-Phenylethyl Caffeate), a naturally occuring compound isolated fromhoneybee hive propolis, is potent and specific inhibitor of NF-κB activation with antioxidant, anticancer, immunomodulatory and antiinflammatory activities.