New7

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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New7

New7 related products

Cat No.	Product Name	CAS No.	Product Description
V5061	CPFX4158	1804962-84-2	CPFX4158 is a novel mannose analog that can be potentially used in transgenic humanized-CEACAM6 mouse as antibacterial agent.
V5130	CS-476 (NSC302998)	41177-35-9	CS 476 (NSC-302998), an orally bioavailable sulphonylurea analog, has been shown to be a potent hypoglycaemic agent.
V4924	CYM5520	1449747-00-5	CYM5520 (CYM-5520), a pyrrolyl ketone analog, is a novel, a potent, selective, and allosteric agonist of sphingosine-1-phosphate receptor 2 with anti-osteoporosis activity.
V4829	DDD85646	1215010-55-1	DDD85646 (DDD-85646) is a novel and potent inhibitor of T.
V4798	Diazepinomicin	733035-26-2	Diazepinomicin (formerly known as TLN-4601; ECO-4601; TLN 4601; BU 4664L), a secondary metabolite produced byMicromonospora sp,is a novel and potent small-molecule inhibitor of the RAS-ERK/RAF/MAPK signaling pathway with potential antineoplastic activity.
V4634	Diflapolin	724453-98-9	Diflapolin is reported to be the first potent dual soluble epoxide hydrolase (sEH)/5-lipoxygenase-activating protein (FLAP) inhibitor.
V5175	Dolastatin 10	110417-88-4	Dolastatin 10 (also known as DLS 10), a peptide-based natural product isolated from the marine molluskDolabela auricularia, is a highly potent antimitotic peptide that inhibits tubulin polymerization with an IC50 value of 1.2μM.
V4795	DT-061	1809427-19-7	DT-061 (also known as DT061; SMAP) is a novel, potent and orally bioavailable activator of PP2A (protein phosphatase 2A) with anticancer effects.
V4730	EBI-1051	1801896-05-8	EBI-1051 is a selective, orally bioavailable MEK inhibitor (antagonist) with IC50 of 3.9 nM.
V4953	Emicerfont	786701-13-1	Emicerfont (also known asGW876008) is a novel and potent corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50of 66 nM.
V5004	ERB-196 (WAY-202196)	550997-55-2	ERB-196 (ERB196; WAY-202196) is a novel, potent, orally bioactive and nonsteroidal selective estrogen receptor-β (ERβ) agonist with the potential to be used for the treatment or prevention of severe sepsis.
V4901	Erteberel	533884-09-2	Erteberel (also known as LY500307) is a novel, potent and selective estrogen receptor beta (ERβ) inhibitor withKiandEC50of 1.54 nM and 3.61 nM, respectively.
V4792	FGTI-2734	1247018-19-4	FGTI-2734 is a novel and potent RAS C-terminal mimetic dualfarnesyl transferase (FT)andgeranylgeranyl transferase-1 (GGT)inhibitor that thwarts Mutant KRAS-Driven Patient-Derived Pancreatic Tumors withIC50s of 250 nM and 520 nM forFTandGGT, respectively.
V4781	G-744	1346669-54-2	G-744 is a novel, highly potent, selective and orally bioavailableBtkinhibitor with anIC50of 2 nM.
V4527	GDC-0339	1428569-85-0	GDC-0339 (GDC0339) is a novel, orally bioavailable, potent and selective small molecule pan-Pim kinase inhibitor with anticancer activity.
V4520	GDC-0834	1133432-49-1	GDC-0834 (R-enantiomer) is a novel, potent and selectiveBTKinhibitor with an in vitroIC50of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivoIC50of 1.1 and 5.6 μM in mouse and rat, respectively.
V4522	GDC-0834 S-enantiomer	1133432-50-4	GDC-0834 S-enantiomeris the S-isomer ofGDC-0834.
V4819	Gemcabene	183293-82-5	Gemcabene (formerly known as PD-72953) is a potent and first-in-class lipid-lowering agent that lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity.
V4551	GNE-049	1936421-41-8	GNE-049 is a novel, highly potent and selective CBP/p300 bromodomaininhibitor with anIC50of 1.1 nM in TR-FRET assay.
V4555	GNE-0946	1677667-24-1	GNE-0946 (GNE0946) is a novel, potent and selectiveRORγ( RORc) inverseagonist with the potential to be used fortreating autoimmune diseases.