| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V4732 | Balamapimod | 863029-99-6 | Balamapimod (formerly also known as MKI-833) is a novel, potent, and reversible Ras/Raf/MEK inhibitor. |
|
V4723 | Guaiapate | 852-42-6 | Guaiapate is a cough suppressant. |
|
V4913 | Bifluranol | 34633-34-6 | Bifluranol (formerly also known as BX-341; traded name Prostarex),a novel fluorinated bibenzyl anti-androgen, is a potent and synthetic nonsteroidal estrogen of the stilbestrol calss related to diethylstilbestrol that has been used as an antiandrogen in the United Kingdom in the treatment of benign prostatic hyperplasia. |
|
V4518 | Toreforant | 952494-46-1 | Toreforant (aslo known as JNJ-38518168) is a novel, potent and selective histamine H4receptor (H4R) antagonist with aKiat the human receptor of 8.4 ± 2.2 nM andexcellent selectivity over other receptors including the other histaminereceptors. |
|
V4910 | Tradipitant | 622370-35-8 | Tradipitant (formerly also known as VLY-686 and LY-686017) is novel, potent and 2nd generation neurokinin-1 (NK-1) receptor antagonist, which showed activity in preclinical anxiety models. |
|
V4890 | Trovirdine HCl | 148311-89-1 | Trovirdine HCl (LY-300046 and PETT-1) is a novel and potent reverse transcriptase inhibitor (RTI) that inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate. |
|
V5071 | Pomiferin (NSC 5113) | 572-03-2 | Pomiferin (formerly known as NSC 5113) is a naturally occuring flavonoid isolated from the fruits ofMaclura pomifera, which acts as an potential inhibitor ofHDAC, with anIC50of 1.05 μM, and also potently inhibitsmTOR(IC50, 6.2 µM). |
|
V5000 | Clovoxamine fumarate | 54739-21-8 | Clovoxamine fumarate (formerly also known as DU 23811) is a potent non-TCA (tricyclic antidepressant) with a dual action in blocking the reuptake of both noradrenaline and serotonin. |
|
V4868 | Lometrexol disodium | 120408-07-3 | Lometrexol is a novel and potent antimetabolite that belongs to the folate class with antineoplastic activity. |
|
V5103 | Calcium methyltetrahydrofolate (NSC173328) | 26560-38-3 | Calcium methyltetrahydrofolate (NSC173328), a synthetic derivative of folic acid, is the calcium salt of levomefolic acid, which has the potential for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers. |
|
V4838 | KKI 5 | 97145-43-2 | KKI 5 is, a synthetic peptide, is a novel and potent serine protease inhibitor that inhibits kallikrein and plasmin. |
|
V5147 | Cyclopiazonic acid (CPA) | 18172-33-3 | Cyclopiazonic acid (also known as CPA), a neurotoxic secondary metabolite (SM) produced byA. |
|
V4623 | Rilapladib (SB659032; GTPL7376) | 412950-08-4 | Rilapladib (formerly aslo known as SB-659032 and GTPL-7376) is a novel, potent and selective lipoprotein-associated phospholipaseA2(Lp-PLA2)inhibitorwith anIC50of 230 pM,also a PAFR (Platelet Activating Factor Receptor) antagonist. |
|
V5098 | Methyl protodioscin (NSC-698790) | 54522-52-0 | Methyl protodioscin (also known as NSC-698790; Smilax saponin B) is a novel furostanol bisglycoside with potent antitumor properties; it is able to reduce proliferation and cause cell cycle arrest. |
|
V4629 | Pulsatilla saponin D | 68027-15-6 | Pulsatilla saponin D (SB365), a naturally-occurring chemical isolated from the root of Pulsatilla koreana, has been used as a traditional medicine for the treatment of several diseases. |
|
V5074 | Amrubicin HCl (Calsed) | 92395-36-3 | Amrubicin HCl (also known as SM-5887 hydrochloride), a third-generation synthetic 9-amino-anthracycline, is a potent DNAtopoisomerase IIinhibitor with antineoplastic activity. |
|
V5030 | Nalmefene HCl | 58895-64-0 | Nalmefene HCl (originally known as nalmetrene; trade name Selincro) is a potent opioid antagonist used primarily in the management of alcohol dependence. |
|
V4945 | Solabegron HC1 | 451470-34-1 | Solabegron (formerly also known as GW 427353; GW-427353; GW-427,353) is a novel, potent and selective agonist for the β3 adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with anEC50value of 22 nM. |
|
V4627 | Inarigivir | 475650-36-3 | Inarigivir (formerly also known as ORI-9020; SB-9000) is a novel and potent dinucleotide which can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. |
|
V4646 | Cytochalasin E | 36011-19-5 | Cytochalasin E, an epoxide-containing analog of cytochalasin B, is a natural product acting as an autophagy inhibitor which enhances chemotherapy-induced cell death andpotently and selectively inhibits the growth of endothelial cells (IC50< 1 nM), impairing angiogenesis and tumor growth. |
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