|
V5198
|
(R)-Oxiracetam (ISF-2522) |
68252-28-8 |
R)-Oxiracetam is the R-isomer of oxiracetam (also known as ISF 2522), which is a widely used nootropic drug and improves memory and learning in patients with cognitive impairments. |
|
V2169
|
(Rac)-LM11A-31 dihydrochloride |
1214672-15-7 |
Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. |
|
V5092
|
Alclofenac |
22131-79-9 |
Alclofenac, adrug of the non-steroidal anti-inflammatory drug (NSAIDs) class, has been used to treat patients with chronic rheumatic diseases but was withdrawn from the UK market in 1979 due to concerns with its association with vasculitis and rash. |
|
V4560
|
Alendronate sodium hydrate |
121268-17-5 |
Alendronate sodium hydrate, the sodium salt of alendronate, is a novel and potent farnesyl diphosphate synthase inhibitor withIC50of 460 nM. |
|
V5116
|
Apomorphine HCl (APL130277; TAK251) |
314-19-2 |
Apomorphine HCl (APL-130277; TAK-251) is a novel and potent dopamine D2 agonist used for the treatment of Parkinsons disease. |
|
V4740
|
BD-AcAc 2 |
1208313-97-6 |
BD-AcAc 2, usually added in diet and given orally, can elevate mean blood ketone bodies of 3.5 mm and lowered plasma glucose, insulin, and leptin in animals. |
|
V2192
|
CCRP2 |
2113650-04-5 |
CCRP2(also known as TLX agonist 1 and SUN-23314) ,is a novel orphan nuclear receptor tailless (TLX, NR2E1) modulator (EC50=1μM; Kd= 650 nM). |
|
V5001
|
Debrisoquin sulfate |
581-88-4 |
Debrisoquine sulfate (Ro5-3307;Debrisochinum; Tendor), the sulfate salt ofDebrisoquin which isa guanidine derivative, is a potent antihypertensive and adrenergic neuron-blocking drugsimilar to guanethidine. |
|
V4897
|
Dexrazoxane (NSC-169780) |
24584-09-6 |
Dexrazoxane (formerly also known as ICRF-187; ADR-529; NSC-169780) is an intracellular iron chelator, which decreases the formation of superoxide radicals, and is mainly used as a cardioprotective agent. |
|
V5073
|
Dicyclohexylamine |
101-83-7 |
Dicyclohexylamine, an inhibitor of Spd synthesis, is a secondary amine with the chemical formula HN(C6H11)2. |
|
V4956
|
Eniluracil (5-Ethynyluracil; GW-776C85) |
59989-18-3 |
Eniluracil (also known as 5-Ethynyluracil; GW776C85) is a novel and potent uracil analog and also a mechanism-based irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD), which increases the oral bioavailability of 5-fluorouracil (5-FU) to 100%, facilitating uniform absorption and predictable toxicity. |
|
V4835
|
EphB1-IN-10 |
2097512-73-5 |
EphB1-IN-10 is a novel, potent, selective and irreversible/covalent inhibitor of receptor tyrosine kinase EphB1. |
|
V4802
|
EXP-3174 |
151801-76-2 |
EXP-3174 (also known as losartan aarboxylic acid), a physiologically active metabolite of losartan produced by cytochrome P450 isoforms in the liver, is a non-peptide, potent angiotensin II (AII) receptor, type 1 (AT1) antagonist, which inhibits the AII induced cellular responses. |
|
V5161
|
Fenazaquin (EL436; XDE 436) |
120928-09-8 |
Fenazaquin(EL-436; XDE-436) is a quinazoline-based insecticide/acaricide which exhibits contact and ovicidal activity against a broad spectrum of mites in grapes, pome fruit, citrus, peaches, cucurbits, tomatoes, cotton and ornamentals. |
|
V4947
|
Fluticasone furoate |
397864-44-7 |
Fluticasone furoate is a topical, intranasal, enhanced affinity synthetic trifluorocorticosteroid with Kd of 0.3 nM. |
|
V4921
|
GLL-398 |
2077980-83-5 |
GLL398 (GLL-398) is a novel, potent, orally bioavailable, and selective estrogen receptor downregulator. |
|
V4545
|
GNE-140 racemate |
1809794-70-4 |
GNE-140 racemate is a novel and potent lactate dehydrogenase (LDHA) inhibitor which is a racemic mixture of (R)-GNE-140 and (S)-GNE-140. |
|
V4863
|
GSK-3008348 |
1629249-33-7 |
GSK-3008348 (GSK3008348), an investigational drug, is a novel and potent integrin alpha(v)beta6 antagonist thatis being developed by GlaxoSmithKline Research and Development Limited (the Sponsor, a pharmaceutical company based in the UK) for the treatment of Idiopathic Pulmonary Fibrosis (IPF). |
|
V2171
|
Isocanadine |
6656-19-5 |
Isocanadine is an isomer of canadine. |
|
V4871
|
LY334370 HCl |
199673-74-0 |
LY-334370 HCl, the hydrochloride of LY-334370, is a novel, potent and selective 5-HT1F receptor agonist with Ki values of 1.6 nM. |