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    SC-26196
    SC-26196

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    This product is for research use only, not for human use. We do not sell to patients.
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    InvivoChem Cat #: V2164
    CAS #: 218136-59-5Purity ≥98%

    Description: SC-26196 is a novel, potent and orally bioactive D6D (Delta6 desaturase) inhibitor with IC50 of 0.2 µM in a rat liver microsomal assay. It completely blocks the conversion of linoleic acid to arachidonic acid (AA). SC-26196 inhibited the desaturation of 2 microM [1-14C] 18:2n-6 by 87-95% in cultured human skin fibroblasts, coronary artery smooth muscle cells, and astrocytes. By contrast, SC-26196 did not affect the conversion of [1-14C]20:3n-6 to 20:4 in the fibroblasts, demonstrating that it is selective for delta6-desaturase.

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    Molecular Formula: C27H29N5

    CAS: 218136-59-5

    Exact Mass: 423.2423
    Molecular Weight: 423.564
    Elemental Analysis: C, 76.56; H, 6.90; N, 16.53

    Synonym: SC 26196; SC26196; SC-26196; 

    SMILES Code: N#CC(C1=CC=CC=C1)(C2=CC=CC=C2)CCCN3CCN(/N=C/C4=CN=CC=C4)CC3

    Chemical Name: (E)-2,2-diphenyl-5-(4-((pyridin-3-ylmethylene)amino)piperazin-1-yl)pentanenitrile




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