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Endogenous Metabolite

Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. Endogenous variables like age, sex, body composition, genetics, and underlying pathologies have an impact on a given body fluid's metabolome. The activity of an enormous variety of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules typically keeps the levels of the enormous variety of unique small-molecule metabolites tightly regulated. In the brain, endogenous small molecules are typically present at levels that are tightly controlled.

Endogenous Metabolite related products

Structure Cat No. Product Name CAS No. Product Description
Resolvin E4 V103015 Resolvin E4 1781227-87-9 Resolvin E4 (RvE4) is an endogenous metabolite that stimulates endocytosis of apoptotic neutrophils and aged erythrocytes.
Retrobradykinin V72814 Retrobradykinin 5991-13-9 Retrobradykinin has the opposite sequence to bradykinin.
Riboflavin-13C5 (Vitamin B2-13C5; Vitamin B2-13C5; E101-13C5) V81298 Riboflavin-13C5 (Vitamin B2-13C5; Vitamin B2-13C5; E101-13C5) Riboflavin-13C5 is a 13C-tagged Riboflavin.
Riboflavin-5-Phosphate-13C4,15N2-1 (Vitamin B2-13C4,15N2-1; Vitamin B2-13C4,15N2-1; E101-13C4,15N2-1) V81299 Riboflavin-5-Phosphate-13C4,15N2-1 (Vitamin B2-13C4,15N2-1; Vitamin B2-13C4,15N2-1; E101-13C4,15N2-1) Riboflavin-5-Phosphate-13C4,15N2-1 is a 13C (carbon 13) and 15N (nitrogen 15) labelled Riboflavin.
Riboflavin-d3 (Vitamin B2-d3; Vitamin B2-d3; E101-d3) V80067 Riboflavin-d3 (Vitamin B2-d3; Vitamin B2-d3; E101-d3) Riboflavin-d3 is the deuterium labelled form of Riboflavin.
Riboflavine phosphate sodium hydrate (Riboflavine 5'-phosphate sodium hydrate) V81879 Riboflavine phosphate sodium hydrate (Riboflavine 5'-phosphate sodium hydrate) 6184-17-4 Riboflavine phosphate sodium hydrate (Riboflavine 5'-phosphate sodium hydrate) is an analogue of Riboflavin (vitamin B2), an essential nutrient for animals.
Ribonuclease T2, Aspergillus oryzae V105862 Ribonuclease T2, Aspergillus oryzae Aspergillus oryzae ribonuclease T2 is a biocatalyst and a key enzyme in new biocatalyst technology.
Ribulose 1,5-bisphosphate V103946 Ribulose 1,5-bisphosphate 24218-00-6 Ribulose 1,5-bisphosphate (RuBP) is an intermediate in photosynthesis and can be metabolized to 3-phosphoglycerate by ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), a key enzyme in the Calvin-Benson-Bassham cycle.
Ricinelaidic acid V102798 Ricinelaidic acid 540-12-5 Ricinoleic acid, a 12-hydroxy fatty acid, is a leukotriene B4 (LTB4) receptor antagonist with a Ki value of 2 μM in porcine neutrophil membranes.
Rostratin A V72842 Rostratin A 752236-16-1 Rostratin A is a cytotoxic disulfide present in the marine-derived fungus Exserohilum rostratum.
rU Phosphoramidite-15N (DMT-2'O-TBDMS-rU phosphoramidite-15N) V81868 rU Phosphoramidite-15N (DMT-2'O-TBDMS-rU phosphoramidite-15N) 1193204-41-9 rU Phosphoramidite-15N (DMT-2'O-TBDMS-rU phosphoramidite-15N) is 15N (Nitrogen 15)-labelled rU Phosphoramidite.
Rubiadin-1-methyl ether V82005 Rubiadin-1-methyl ether 7460-43-7 Rubiadin-1-methyl ether is an anthraquinone compound in Morinda officinalis, which can inhibit osteoclastic bone resorption by inhibiting the phosphorylation level of NF-κB p65, degrading IκBα protein, and reducing the nuclear translocation of p65.
Rugulotrosin A V91092 Rugulotrosin A 685135-81-3 Rugulotrosin A is an antibiotic originally isolated from Penicillium.
S-(2,4-Dinitrophenyl)glutathione V82035 S-(2,4-Dinitrophenyl)glutathione 26289-39-4 S-(2,4-Dinitrophenyl)glutathione is a substrate of glutathione-S-transferase.
S-(2-Carboxypropyl)-L-cysteine (β-Isobuteine) V72459 S-(2-Carboxypropyl)-L-cysteine (β-Isobuteine) 6852-42-2 S-(2-Carboxypropyl)-L-cysteine (β-Isobuteine) is a urinary metabolite and a metabolic marker of leigh-like syndrome.
S-(3-Hydroxydodecanoate)-CoA V105806 S-(3-Hydroxydodecanoate)-CoA 72059-49-5 (S)-3-Hydroxydodecanoyl-CoA, a CoA, is a metabolite found or produced in Escherichia coli (strains K12, MG1655).
S-Adenosyl-L-methionine iodide (S-Adenosyl methionine iodide; Ademetionine iodide; AdoMet iodide) V70996 S-Adenosyl-L-methionine iodide (S-Adenosyl methionine iodide; Ademetionine iodide; AdoMet iodide) 3493-13-8 S-(5'-Adenosyl)-L-methionine iodide (S-Adenosyl-L-methionine iodide) is an important methyl donor present in all organisms.
S-Adenosyl-L-methionine tosylate (S-Adenosyl methionine tosylate; Ademetionine tosylate; AdoMet tosylate) V72299 S-Adenosyl-L-methionine tosylate (S-Adenosyl methionine tosylate; Ademetionine tosylate; AdoMet tosylate) 52248-03-0 S-Adenosyl-L-methionine tosylate is endogenously produced from methionine and ATP through the action of methionine adenosyltransferase and is an important orally bioactive methyl donor.
S-Adenosyl-L-methionine-13C (S-Adenosyl methionine-13C; Ademetionine-13C; AdoMet--13C) V72873 S-Adenosyl-L-methionine-13C (S-Adenosyl methionine-13C; Ademetionine-13C; AdoMet--13C) 74084-24-5 S-Adenosyl-L-methionine-13C is 13C (carbon 13) labelled S-Adenosyl-L-methionine.
S-Adenosyl-L-methionine-d3 (S-Adenosyl methionine-d3; Ademetionine-d3; AdoMet-d3) V81996 S-Adenosyl-L-methionine-d3 (S-Adenosyl methionine-d3; Ademetionine-d3; AdoMet-d3) 68684-40-2 S-Adenosyl-L-methionine-d3 is the deuterated form of S-Adenosyl-L-methionine.
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