Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V72190 | 28-Epirapamycin | 253431-35-5 | 28-Epirapamycin is an impurity of Rapamycin. |
|
V72296 | 2S,4R-Sacubitril (Sacubitril Valsartan impurity 16) | 2307668-79-5 | 2S,4R-Sacubitril is an impurity of Sacubitri. |
|
V104956 | 2α-Methyl-5α-androstan-17-one-3α-glucuronide | 361432-78-2 | 2α-Methyl-5α-androstan-17-one-3α-glucuronide is a metabolite of Drostanolone. |
|
V72135 | 3'-Hydroxy Repaglinide-d5 | 1352792-15-4 | 3'-Hydroxy Repaglinide-d5 is the deuterium labelled form of 3'-Hydroxy Repaglinide. |
|
V72134 | 3,4,5-Trimethoxyphenylacetic acid | 951-82-6 | 3,4,5-Trimethoxyphenylacetic acid is a metabolite of Mescaline. |
|
V72120 | 3,4-Dehydro Cilostazol (OPC-13015) | 73963-62-9 | 3,4-Dehydro Cilostazol (OPC-13015) is the bioactive metabolite of cilostazol (CLZ). |
|
V107393 | 3,4-Dihydroxyamphetamine hydrochloride | 828-06-8 | 3,4-Dihydroxyamphetamine (α-methyldopamine) (hydrochloride) is a minor metabolite of 3,4-methylenedioxymethamphetamine (MDMA). |
|
V105183 | 3,4-Dimethylmethcathinone metabolite hydrochloride | 4865-62-7 | 3,4-Dimethylmethcathinone metabolite hydrochloride is a metabolite of 3,4-dimethylmethcathinone. |
|
V72232 | 3-(1-Nitrosopyrrolidin-2-yl)pyridine | 80508-23-2 | 3-(1-Nitrosopyrrolidin-2-yl)pyridine is a major tobacco-specific nitrosamine. |
|
V72118 | 3-Amino-2-oxazolidinone (AOZ) | 80-65-9 | 3-Amino-2-oxazolidinone (AOZ) is the metabolite of furazolidinone. |
|
V103359 | 3-Hydroxy darifenacin | 206048-82-0 | 3-Hydroxydarifenacin is a metabolite of darifenacin. |
|
V105310 | 3-Hydroxy desalkylgidazepam | 37891-18-2 | 3-Hydroxydesalkylgedazepam (Compound 2) is the active metabolite of gedazepam and desalkylgedazepam. |
|
V107899 | 3-Hydroxy-4-methyl-2(5H)-thiophenone | 34876-35-2 | 3-Hydroxy-4-methyl-2(5H)-thiophenone (Compound 18), a pyrazine derivative, is the major acidic degradation product of cephalexin. |
|
V71650 | 3-Hydroxycarbofuran (3-Hydroxycarbofuran) | 16655-82-6 | 3-Hydroxycarbofuran is the major metabolite of Carbofuran and is a reversible inhibitor of acetylcholinesterase (AChE). |
|
V102766 | 3-Hydroxyflunitrazepam | 67739-71-3 | 3-Hydroxyflunitrazepam (3-OH FNTZ) is the major metabolite of flunitrazepam (FNTZ) produced by CYP3A4 via the 3-hydroxylation pathway (Km = 286 μM), which is the major metabolic pathway (>80%) in liver microsomes. |
|
V72211 | 3-Hydroxyphenazepam | 70030-11-4 | 3-Hydroxyphenazepam is the bioactive metabolite of Cinazepam. |
|
V102597 | 3-Hydroxyquinine | 53467-23-5 | 3-Hydroxyquinine is a metabolite of quinidine. |
|
V72171 | 3-Methyl-2-quinoxalinecarboxylic acid (MQCA) | 74003-63-7 | 3-Methyl-2-quinoxalinecarboxylic acid (MQCA) is an important N-oxide reducing metabolite of Quinocetone or Olaquindox, which can effectively suppress the growth of Zhang's hepatocytes through S-phase cell cycle arrest. |
|
V105945 | 3-Methylcrotonyl CoA | 6712-03-4 | 3-Methylcrotonyl-CoA is a key metabolic intermediate in the leucine degradation pathway and is converted into 3-methylglutaryl-CoA by 3-methylcrotonyl-CoA carboxylase. |
|
V103179 | 3-O-Acetylbetulin | 27570-20-3 | 3-O-Acetylbetulin, a derivative of betulin, is a steroid regulatory element binding protein (SREBP) inhibitor. |
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