Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.
Structure | Cat No. | Product Name | CAS No. | Product Description |
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V106638 | Pantoprazole sulfide | 102625-64-9 | Pantoprazole sulfide is a metabolite of pantoprazole and a proton pump inhibitor. |
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V105389 | PB-22 N-(4-Hydroxypentyl)-3-carboxyindole metabolite | 2704733-57-1 | PB-22 N-(4-hydroxypentyl)-3-carboxyindole metabolite is a metabolite of PB-22. |
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V107535 | PB-22 N-pentanoic acid metabolite | 2071638-22-5 | PB-22 N-valeric acid metabolite is a metabolite of PB-22. |
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V90271 | Pergolide sulfone | 72822-03-8 | Pergolide sulfone is a metabolite of Pergolide. |
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V72242 | Perindopril acyl-β-D-glucuronide | 120398-66-5 | Perindopril acyl-β-D-glucuronide is a metabolite of Perindopril. |
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V72287 | Perphenazine sulfoxide | 10078-25-8 | Perphenazine sulfoxide is the sulfoxide metabolite of Perphenazine, formed by the oxidation of Perphenazine. |
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V103042 | Piribedil N-oxide | 53954-71-5 | Piribedil N-oxide is a metabolite of the dopamine receptor agonist piribedil. |
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V107361 | Prasugrel hydroxy thiolactone | 947502-66-1 | Prasugrel hydroxythiolactone (Compound M18) is a metabolite of prasugrel. |
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V105918 | Pregnanetriol | 1098-45-9 | Pregnanetriol is a metabolite of 17α-hydroxyprogesterone. |
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V72163 | Pseudoerythromycin A enol ether (LY267108) | 105882-69-7 | Pseudoerythromycin A enol ether (LY267108) is a degradation product of erythromycin. |
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V72151 | Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide) | 38934-20-2 | Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a metabolite of Quercetin, can be extracted from the Uncarina species in Madagascar. |
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V72146 | Quetiapine sulfoxide hydrochloride (quetiapine sulfoxide hydrochloride; Quetiapine S-oxide hydrochloride) | 2448341-72-6 | Quetiapine sulfoxide HCl (Quetiapine S-oxide HCl) is the major metabolite of Quetiapinem. |
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V102951 | Quinidine N-oxide | 70116-00-6 | Quinidine N-oxide is a pharmacologically inactive metabolite of quinidine. |
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V72248 | Radafaxine ((S,S)-Hydroxybupropion; GW-353162A free base; BW-306U free base) | 192374-14-4 | Radafaxine ((S,S)-Hydroxybupropion) is an antidepressant compound. |
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V70587 | Ramelteon metabolite M-II-d3 | 1246812-22-5 | Ramelteon metabolite M-II-d3 is the deuterium labelled form of Ramelteon metabolite M-II. |
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V102528 | Regorafenib N-oxide and N-desmethyl (M5) | 835621-12-0 | Regorafenib N-oxide and N-desmethyl (M5) (N-desmethylregorafenib N-oxide) are active metabolites of sorafenib and are metabolized by CYP3A4. |
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V69537 | Regorarafénib N-oxyde-d3(M2) (Regorafénib N-oxide (M2 metabolite) impurity 13-d3) | 1333489-03-4 | Regorafénib N-oxyde-d3(M2) is the deuterated form of Regorafénib N-oxyde M2. |
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V72175 | Resveratrol-3-O-sulfate sodium | 858127-11-4 | Resveratrol-3-O-sulfate (sodium) is a metabolite of Resveratrol. |
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V72276 | Ritalinic acid (Ritalinic acid; Ritalinate) | 19395-41-6 | Ritalinic acid (Ritalinate) is the major inactive urinary metabolite of Methylphenidate. |
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V105892 | Rivaroxaban EP Impurity I | 1151893-81-0 | Rivaroxaban EP Impurity I (Imp I) is the impurity reference substance for Rivaroxaban EP. |