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Reactive Oxygen Species

Reactive Oxygen Species

Reactive oxygen species (ROS) are radical and non-radical oxygen species produced by the partial reduction of oxygen, including superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•). Endogenous ROS are produced by cells during their normal oxidative metabolism in the mitochondria as well as when they react to xenobiotics, cytokines, and bacterial invasion.

By directly inhibiting MAPK phosphatases, ROS also activates MAPK pathways. Through PTEN, ROS produced by growth factor stimulation are capable of reversibly controlling the redox state of the PI3K pathway. The cellular response to ROS may involve the activation of autophagy.

Reactive Oxygen Species related products

Structure Cat No. Product Name CAS No. Product Description
(+)-Schisandrin B ((+)-Schisandrin B) V72941 (+)-Schisandrin B ((+)-Schisandrin B) 82467-52-5 (+)-Schisandrin B is an enantiomer of Schisandrin B.
(+)-Secolongifolene-diol V103137 (+)-Secolongifolene-diol 53587-37-4 (+)-Secolongifolene-diol is a sesquiterpene isolated from the marine fungus Drechslera sp.
(-)-Lyoniresinol 9'-O-glucoside V72973 (-)-Lyoniresinol 9'-O-glucoside 143236-02-6 (-)-Lyoniresinol 9'-O-glucoside is an inhibitor (blocker/antagonist) of ROS.
(2S,3R)-DEPMPO-Biotin V102914 (2S,3R)-DEPMPO-Biotin 936224-52-1 (2S,3R)-DEPMPO-Biotin is a spin trap composed of DEPMPO and Biotin.
(E/Z)-GSK5182 V67649 (E/Z)-GSK5182 2699724-40-6 (E/Z)-GSK5182 is the racemate of (E)-GSK5182 and (Z)-GSK5182.
(E/Z)-MCB-613 V88532 (E/Z)-MCB-613 296792-62-6 (E/Z)-MCB-613 is a pan-steroid receptor coactivator (SRC) stimulator.
(±)-Carnitine-d9 chloride (DL-Carnitine-d9 (chloride)) V72906 (±)-Carnitine-d9 chloride (DL-Carnitine-d9 (chloride)) 1219386-75-0 (±)-Carnitine-d9 (chloride) is the deuterated form of (±)-Carnitine chloride.
(±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) V72939 (±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) 69097-97-8 (±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) was extracted from Angelica keiskei, a cold-resistant perennial herb of the Apiaceae family.
1,3-Diphenylisobenzofuran (DPBF) V67090 1,3-Diphenylisobenzofuran (DPBF) 5471-63-6 1,3-Diphenylisobenzofuran (DPBF) is used as a selective probe for the detection and quantification of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS).
1-Oleoyl-2-palmitoylglycerol V107369 1-Oleoyl-2-palmitoylglycerol 3331-34-8 1-Oleoyl-2-palmitoylglycerol is a diacylglycerol containing oleic acid and palmitic acid at the sn-1 and sn-2 positions of the glycerol backbone.
1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc V97444 1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc 1287795-07-6 1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc is a phospholipid-porphyrin polymer.
1-甲氧基-5-甲基酚嗪鎓硫酸甲酯盐 V29766 Methoxy-PMS 65162-13-2 Methoxy-PMS (1-Methoxy PMS) is a stable electron transport intermediary.
2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside V72945 2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside 1447969-66-5 2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside is a chlorophenyl glycoside compound in Lilium brownie var.
2,4,7-Trihydroxy-9,10-dihydrophenanthrene V72921 2,4,7-Trihydroxy-9,10-dihydrophenanthrene 70205-52-6 2,4,7-Trihydroxy-9,10-dihydrophenanthrene is a dihydrophenanthrene analogue that can be found in Pholidota chinensis Lindl.
2-Selenouracil V72904 2-Selenouracil 16724-03-1 2-Selenouracil is an effective photosensitizer used in photodynamic therapy.
3′-Hydroxy-4′-O-methylglabridin V72965 3′-Hydroxy-4′-O-methylglabridin 175554-11-7 3′-Hydroxy-4′-O-methylglabridin is an antioxidant that effectively prevents NADH-dependent peroxidation.
3-Demethylcolchicine V72896 3-Demethylcolchicine 7336-33-6 3-Demethylcolchicine is a metabolite of colchicine.
3-Indoleacrylic acid-d4 V106627 3-Indoleacrylic acid-d4 3-Indoleacrylic Acid-d4 is a deuterium labeled 3-Indoleacrylic Acid.
3-Methoxy-9H-Carbazole V88404 3-Methoxy-9H-Carbazole 18992-85-3 3-Methoxy-9H-Carbazole induces increased caspase-3 activity and the generation of reactive oxygen species.
4-Methyl-6-phenyl-2H-pyranone V72955 4-Methyl-6-phenyl-2H-pyranone 4467-30-5 4-Methyl-6-phenyl-2H-pyranone may be utilized to prepare N-hydroxypyridone analogues that protect astrocytes from hydrogen peroxide-induced toxicity by improving mitochondrial function.
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