Hepatitis B virus, also known as HBV or Orthohepadnavirus, is a type of virus that belongs to the Hepadnaviridae family of viruses. Hepatitis B is brought on by the virus HBV. The ground squirrel hepatitis virus, the woodchuck hepatitis virus, and the woolly monkey hepatitis B virus are the other three species that make up the Orthohepadnavirus, of which the hepatitis B virus is the type species. The Hepadnaviridae family includes the genus as a member. Based on antigenic epitopes found on its envelope proteins, HBV is classified into four major serotypes (adr, adw, ayr, ayw), and eight genotypes (A-H) based on the genome's overall nucleotide sequence variation.The genotypes are used to track the evolution and spread of the virus because they have a distinct geographic distribution. The severity of the disease, the progression and propensity for complications, the response to treatment, and perhaps vaccination, are all impacted by genotype differences.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V54176 | HBV-IN-9 | 2170998-69-1 | HBV (hepatitis B virus)-IN-9 (example 20) is a potent HBsAg (HBV (hepatitis B virus) surface antigen) inhibitor (IC50=10 nM) and HBV (hepatitis B virus) DNA replication inhibitor (IC50=0.15 nM). |
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V88258 | HBV/HDV-IN-3 | 2883679-03-4 | HBV/HDV-IN-3 (Compd 1) is a dual inhibitor of HBV and HDV, with an EC50 value of <50 nM for HBV. |
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V88253 | HBV/HDV-IN-4 hydrochloride | 3034059-40-7 | HBV/HDV-IN-4 hydrochloride (Compd 4) is a dual inhibitor of HBV and HDV, with an EC50 value of <50 nM for HBV. |
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V54188 | Hepatitis B Virus Receptor Binding Fragment (hepatitis B peptide 4980) | 114495-85-1 | Hepatitis B Virus Receptor Binding Fragment (hepatitis B peptide 4980) is a synthetic peptide analog that specifically binds to Hep G2 cells. |
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V51949 | Inarigivir ammonium (ORI-9020 ammonium; SB-9000 ammonium) | 2172788-92-8 | Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral compound that significantly reduces HBV (hepatitis B virus) DNA in transgenic mice expressing hepatitis B virus. |
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V4501 | JNJ-632 | 1572510-42-9 | JNJ-632 is a novel and potent hepatitis B virus (HBV) capsid assembly modulator (CAM). |
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V54201 | Lagociclovir valactate | 1001670-19-4 | Lagociclovir valactate is the prodrug of Lagociclovir. |
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V106397 | Libevitug | Libevitug is a human IgG1λ2 antibody against HBV, and the corresponding isotype control is: human IgG1 lambda2, isotype control. | |
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V51847 | LPRP-Et-97543 | 84638-48-2 | LPRP-Et-97543 is a potent anti-HBV (hepatitis B virus) active molecule. |
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V102535 | Morphothiadin mesylate | 1646361-04-7 | Morphine (GLS4) mesylate is a potent inhibitor of wild-type and adefovir-resistant HBV replication with IC50 of 12 nM. |
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V54180 | Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) | 123410-65-1 | Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) is an HBV (hepatitis B virus) inhibitor. |
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V41067 | Oleana-2,12-dien-28-oic acid | 272108-04-0 | Oleana-2,12-dien-28-oic acid is an HBV (hepatitis B virus)-DNA inhibitor, HBsAg and HBeAg inhibitor. |
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V54178 | Oxynitidine | 548-31-2 | Oxynitidine is an HBV (hepatitis B virus) inhibitor (ID50=30.8 µg/mL), which can effectively inhibit the DNA replication activity of HBV (hepatitis B virus). |
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V54203 | Periglaucine B ((+)-Periglaucine B) | 1025023-05-5 | Periglaucine B ((+)-Periglaucine B) is an alkaloid and HBsAg inhibitor. |
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V54181 | Picroside IV (Picroside IV) | 211567-04-3 | Picroside IV is an iridoid glycoside derived from the underground parts of Coptidis rhizome. |
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V88259 | PROTAC PAPD5 degrader 1 | PROTAC PAPD5 degrader 1 (compound 12b) inhibits hepatitis A (HAV) and hepatitis B virus (HBV) in vitro and in vivo with IC 50 and CC50 of 10.59 μM and > 50 μM in Huh7 cells, respectively. | |
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V3656 | RG7834 S-isomer | 2072057-17-9 | RG7834 S-isomer, also known asRO 7020322 is the S-enantiomer of RG7834 (RO-7020322) which is a novel, potent and orally bioavailable inhibitor of HBV viral gene expression which blocks viral antigen and virion production. |
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V7268 | RO6889678 | 1578153-27-1 | RO6889678 (RO-6889678) is a novel and potent inhibitor of HBV, inhibitingHBV capsid formation. |
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V88255 | SAG-524 | 2246696-89-7 | SAG-524 is a potent, oral small molecule inhibitor of HBV viral replication. |
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V54182 | Sanggenol P | 1351931-30-0 | Sanggenol P is a flavonoid that has anti-HBV (hepatitis B virus) activity against HepG2.2.15 cell line in vitro. |
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