Protons can be transported across a biological membrane by the proton pump, an essential membrane protein. Mechanisms are based on the Q cycle or conformational changes in the protein structure. The proton pump uses energy during cell respiration to move protons from the mitochondrion's matrix to the intermembrane space. Due to the fact that there are more protons outside the matrix than inside, an active pump creates a gradient of proton concentration across the inner mitochondrial membrane.An electrochemical potential difference that functions similarly to a battery or energy storage unit for the cell is produced by the difference in pH and electric charge (while disregarding variations in buffer capacity). As the process generates potential energy, it can also be compared to cycling uphill or charging a battery for later use. Instead of producing energy, the proton pump creates a gradient that stores energy for later use.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V4894 | Rabeprazole Sodium (LY307640 sodium) | 117976-90-6 | Rabeprazole sodium (LY-307640 sodium) is a novel, potent and 2nd-generation proton pump inhibitor (PPI) that is used as an antiulcer drug. |
|
V81551 | Tegoprazan-d6 (CJ-12420-d6; RQ-00000004-d6) | Tegoprazan-d6 is a stable isotope of Tegoprazan. | |
|
V1640 | Tenatoprazole (TU-199) | 113712-98-4 | Tenatoprazole (formerly known as TU-199; TU 199;Ulsacare; Protop) is a prodrug of the proton pump inhibitor (PPI) class with the potential for the treatment of gastroesophageal reflux disease. |
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V16456 | Tiludronate disodium | 149845-07-8 | Tiludronate (Tiludronate disodium; Tiludronic Acid disodium) is a novel and potent bisphosphonate agent which prevents postmenopausal bone loss and is used for treatment of Paget's disease of bone (osteitis deformans) in human medicine. |
|
V74233 | Tiludronate disodium hemihydrate (Tiludronic acid disodium hemihydrate) | 155453-10-4 | Tiludronate (Tiludronic Acid) disodium hemihydrate is an orally bioactive bisphosphonate that exerts bone modulating effects. |
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V28031 | Vonoprazan (TAK-438) | 881681-00-1 | Vonoprazan (TAK-438) is a novel,orally bioavailable and potent P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. |
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V74228 | Vonoprazan Fumarate (Vonoprazan Fumarate; TAK-438) | 881681-01-2 | Vonoprazan Fumarate (TAK-438) is a proton pump inhibitor (PPI), a potent, orally bioactive potassium-competitive acid blocker (P-CAB) with anti-secretory activity . |
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V74230 | Zastaprazan (JP-1366) | 2133852-18-1 | Zastaprazan (JP-1366) is a proton pump inhibitor (WO2018008929). |
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V1636 | Zinc Pyrithione (OM-1563) | 13463-41-7 | Zinc pyrithione (formerly known as OM-1563; AI3-62421; BCJ; BC-JOM1563;Biocut ZP, Finecide ZPT),an ingredient of commercial anti-dandruff shampoos, is an antifungal and antibacterial agent thatdisrupts membrane transport by blocking the proton pump. |
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