The role of tau as a microtubule-associated protein in neurons is well established. They play major roles in preserving the stability of microtubules in axons and are widely distributed in central nervous system (CNS) neurons. However, in a variety of neurodegenerative disorders collectively known as tauopathies, aberrant assembly of tau into insoluble aggregates is accompanied by synaptic dysfunction and neural cell death.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V70064 | Semorinemab (RG 6100; RO7105705; MTAU-9937A) | 2159141-27-0 | Semorinemab (RG 6100) is an anti-Tau humanized IgG4 monoclonal antibody (mAb) that targets the N-terminal portion of the Tau protein (amino acid (AA) residues 6-23). | |
V32942 | T807 (AV1451) | 1415379-56-4 | T807 is a new tau positron emission tomography (PET) tracer. | |
V76448 | Tau ASO-12 (murine) (sodium) | TauASO-12 (murine) (sodium) is an antisense oligonucleotide (ASO) used to reduce murine Tau and may be used for studying AD/Alzheimer's disease. | ||
V70086 | Tau Peptide (1-16) (human) | 2022956-53-0 | Tau Peptide (1-16) (human) is a fragment of Tau protein. | |
V70104 | Tau Peptide (244-274) (Repeat 1 Domain) | 330456-24-1 | Tau Peptide (244-274) (Repeat 1 Domain) is a fragment of Tau protein. | |
V70085 | Tau Peptide (245-274) (Repeat 1 Domain) | 1428134-39-7 | Tau Peptide (245-274) (Repeat 1 Domain) is a fragment of Tau protein. | |
V70101 | Tau Peptide (255-314) (Repeat 2 Domain) (human) | 2022995-68-0 | Tau Peptide (255-314) (Repeat 2 Domain) (human) is a bioactive peptide discovered by peptide screening. | |
V70105 | Tau Peptide (268-282) | 330456-37-6 | Tau Peptide (268-282) is a bioactive peptide discovered by peptide screening. | |
V70079 | Tau Peptide (273-284) | 1663490-91-2 | Tau Peptide (273-284) is a fragment of Tau protein. | |
V70092 | Tau Peptide (274-288) | 330456-39-8 | Tau Peptide (274-288) is a bioactive peptide discovered by peptide screening. | |
V70070 | Tau Peptide (275-305) (Repeat 2 domain) | 330456-25-2 | Tau Peptide (275-305) (Repeat 2 domain) is the R2 fragment of Alzheimer's Tau protein, corresponding to the second repeat unit of the microtubule-binding domain, and is considered to be the key to the biochemical properties of the entire Tau protein. | |
V70071 | Tau Peptide (277-291) | 330456-40-1 | Tau Peptide (277-291) is a bioactive peptide discovered by peptide screening. | |
V70108 | Tau Peptide (294-305) (human) | 1428135-29-8 | Tau Peptide (294-305) (human) is a fragment of Tau protein. | |
V70093 | Tau Peptide (295-309) | 330456-46-7 | Tau Peptide (295-309) is a bioactive peptide discovered by peptide screening. | |
V70098 | Tau Peptide (298-312) | 330456-47-8 | Tau Peptide (298-312) is a bioactive peptide discovered by peptide screening. | |
V70103 | Tau Peptide (301-315) | 330456-48-9 | Tau Peptide (301-315) is a bioactive peptide discovered by peptide screening. | |
V70081 | Tau Peptide (304-318) | 330456-49-0 | Tau Peptide (304-318) is a bioactive peptide discovered by peptide screening. | |
V70091 | Tau Peptide (306-317) | 1003007-59-7 | Tau Peptide (306-317) is a bioactive peptide discovered by peptide screening. | |
V70078 | Tau Peptide (306-336) (Repeat 3 Domain) | 330456-26-3 | Tau Peptide (306-336) (Repeat 3 Domain) is a fragment of Tau protein. | |
V70080 | Tau Peptide (307-321) | 330456-50-3 | Tau Peptide (307-321) is a bioactive peptide discovered by peptide screening. |