A family of enzymes known as monoamine oxidases (MAO) catalyzes the oxidation of monoamines. In the majority of the body's cell types, they are discovered bound to the mitochondria's outer membrane. They are a member of the flavin-containing amine oxidoreductase protein family. The oxidative deamination of monoamines is catalyzed by monoamine oxidases. By using oxygen to remove an amine group from a molecule, the resulting aldehyde and ammonia are produced.Flavoproteins are monoamine oxidases because they have the cofactor FAD covalently bound to them. MAO dysfunction is thought to be the cause of a number of psychiatric and neurological disorders due to the critical part MAOs play in the inactivation of neurotransmitters. While MAO-B inhibitors are used alone or in combination to treat Alzheimer's and Parkinson's diseases, MAO-A inhibitors have antidepressant and antianxiety properties.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V70659 | Tisolagiline (KDS2010) | 1894207-44-3 | Tisolagiline (KDS2010) is a reversible MAO-B inhibitor used in Parkinson's disease (PD) research. | |
V70680 | Tranylcypromine (SKF 385) | 155-09-9 | Tranylcypromine (SKF 385) is a potent MAO (monoamine oxidase) inhibitor. | |
V70681 | WAY-620147 | 515866-67-8 | WAY-620147 (compound 6) is an N-(2-morpholinoethyl)nicotinamide analogue that can inhibit monoamine oxidase (Monoamine Oxidase). |