The ion channel known as the calcium channel exhibits selective permeability to calcium ions. Although there are ligand-gated calcium channels as well, it is sometimes referred to as a voltage-dependent calcium channel. Even though the concentration of Na+ outside of cells is 70 times higher than that of Ca2+, voltage-gated calcium (CaV) channels catalyze a rapid, highly selective influx of Ca2+ into cells. A side effect of some calcium channel blockers is that they slow your heart rate, which helps to lower blood pressure, treat angina, and regulate irregular heartbeats.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V81217 | Propiverine-d7 hydrochloride (propiverine d7 hydrochloride) | Propiverine-d7 ( HCl) is the deuterated form of Propiverine HCl. | |
|
V71490 | ProTx-I | 484598-35-8 | ProTx-I, a toxin derived from Thrixopelma pruriens, is a potent and specific CaV3.1 channel blocker with IC50s of 0.2 μM and 31.8 μM for hCAV3.1 and hCaV3.2, respectively. |
|
V71485 | Ranolazine-d3 (ranolazine d3) | 1054624-77-9 | Ranolazine-d3 is the deuterated form of Ranolazine. |
|
V87167 | Rp-8-Br-cGMPS | 150418-07-8 | Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is a potent Ca2+-ATPase activator. |
|
V71506 | Rp-8-Br-cGMPS sodium salt (Rp-8-bromo-Cyclic GMPS sodium salt) | 208445-06-1 | Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is an effective Ca2+-ATPase activator. |
|
V71469 | Ruthenium red (Ruthenium red; Ammoniated ruthenium oxychloride) | 11103-72-3 | Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye extensively used for observation of cells, tissues and vegetative bacteria under electron microscopy (EM). |
|
V78416 | RyR2 stabilizer-1 | RyR2 stabilizer-1 (compound 12a) is a potent RyR2 stabilizer and SERCA2a activator with EC50s of 2.7 μM and 383 nM for RyR2 and SERCA2, respectively. | |
|
V96655 | SB-237376 free base | 179258-59-4 | SB-237376 (free base) is a potassium channel and calcium channel blocker. |
|
V71515 | sFTX-3.3 | 141997-14-0 | sFTX-3.3 is a Ca2+ channel antagonist (inhibitor) with IC50 of approximately 0.24 mM and 0.70 mM for P-type and N-type Ca2+ channels, respectively. |
|
V71472 | SG-094 | 2922283-37-0 | SG-094 is a potent TPC2 inhibitor (antagonist) with anti-proliferation activity. |
|
V71476 | SNX-482 | 203460-30-4 | SNX-482, a peptidyl toxin from the spider Hysterocrates gigas, is a potent, high-affinity, selective and voltage-dependent R-type CaV2.3 channel blocker with IC50 of 30 nM. |
|
V87130 | Sornidipine | 95105-77-4 | Sornidipine is a calcium channel blocker. |
|
V102183 | SR33805 oxalate | 121346-33-6 | SR33805 oxalate is a potent Ca2+ channel antagonist with EC50 values of 4.1 nM and 33 nM under depolarizing and polarizing conditions, respectively. |
|
V85574 | Sulcardine | 343935-60-4 | |
|
V97485 | Sulcardine hydrochloride | 343935-48-8 | Sucadin is a multi-ion channel blocker that reduces INa and ICa with IC50 of 26.9 µM and 69.2 µM, respectively. |
|
V71503 | T-Type calcium channel inhibitor 2 | 2771965-57-0 | T-Type calcium channel inhibitor 2 (compound 6g) is a potent T-type calcium channel inhibitor. |
|
V102214 | Tamolarizine | 93035-32-6 | Tamorazine is a calcium channel blocker. |
|
V87783 | TAT-CBD3A6K | 1505463-57-9 | TAT-CBD3A6K is a modified TAT-CBD3 peptide. |
|
V71511 | Taurolithocholic Acid-d5 sodium | 1265476-97-8 | Taurolithocholic Acid-d5 (sodium) is the deuterated form of Taurolithocholic acid sodium salt. |
|
V102500 | Terflavoxate | 86433-40-1 |
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