Prostaglandin receptor, a sub-family of cell surface seven-transmembrane receptors, are the G-protein-coupled receptors.Ten distinct prostaglandin receptors on different cell types are currently known. G-protein-coupled receptors are a subclass of cell surface seven-transmembrane receptors that prostaglandins bind to. The following are the names of these receptors: FP-FP, IP1-2-IP1, IP2 receptors, TP-TP receptor, EP1-4-EP1, EP2, EP3, and EP4 receptors. A class of lipid molecules known as prostaglandins, which are produced enzymatically from fatty acids and resemble hormones, play vital roles in the bodies of animals. Ten distinct prostaglandin receptors on different cell types are currently known.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V74465 | PDC31 (THG113.31; ILGHXDYK) | 634586-40-6 | PDC31 (THG113.31; ILGHXDYK) is an allosteric and noncompetitive inhibitor of the FP Prostaglandin Receptor. |
|
V74467 | Pexopiprant | 932708-14-0 | Pexopiprant is an oral antagonist of prostaglandin D2 receptor 2 (DP2) with Ki < 100nM. |
|
V1881 | PF-04418948 | 1078166-57-0 | PF-04418948 is a novel, potent and selective prostaglandin EP2 receptor antagonist. |
|
V7294 | PGD2-IN-1 | 885066-67-1 | PGD2-IN-1 is a DP receptor blocker (antagonist), disclosed in patent WO 2006044732 A2, example compound 15 (d), with IC50 of 0.3 nM. |
|
V27653 | Pizuglanstat | 1244967-98-3 | Pizuglanstat is a novel and potent prostaglandin D synthase inhibitor with the potential forDuchenne muscular dystrophy (DMD). |
|
V74484 | Prostaglandin D3 (PGD3) | 71902-47-1 | Prostaglandin D3 (PGD3) is a prostaglandin compound that works as an inhibitor (blocker/antagonist) of platelet aggregation and a modulator of autonomic neurotransmission in humans. |
|
V4216 | Ramatroban | 116649-85-5 | Ramatroban is a novel, potent and selectiveantagonist of thromboxane A2(TxA2) with an IC50of 14 nM. |
|
V3669 | RO1138452 | 221529-58-4 | RO1138452 is a novel, potent and selective antagonist of the IP (prostacyclin) receptor. |
|
V74460 | SC 51089 free base | 146033-03-6 | SC 51089 free base is a selective prostaglandin receptor EP1 antagonist (inhibitor) with Kis of 1.3, 11.2, 17.5 and 61.1 μM for EP1, TP, EP3 and FP receptors respectively. |
|
V74470 | Selexipag-d7 | 1265295-21-3 | Selexipag-d7 is the deuterium labelled form of Selexipag. |
|
V5219 | Setipiprant （ACT-129968; KYTH-105) | 866460-33-5 | Setipiprant (ACT-129968 and KYTH-105) is a novel, potent, orally bioavailable and selective CRTH2 antagonist. |
|
V74459 | Sulprostone (Sulprostone; SHB 286; CP-34089; ZK-57671) | 60325-46-4 | Sulprostone (SHB 286) is a specific EP3 receptor agonist. |
|
V4395 | TAFLUPROST | 209860-87-7 | Tafluprost (formerly MK-2452; MK2452; AFP-168; Taflotan; Zioptan) is a prostaglandin (PG) analog used as ananti-glaucoma drug. |
|
V3782 | Taprenepag isopropyl | 1005549-94-9 | Taprenepag isopropyl (foremrly PF-04217329 or PF-4217329) is a prodrug of CP-544326 (Taprenepag) which is a potent and selective agonist of EP2 (prostaglandin EP receptor 2) with IC50 of 10nM and EC50 of 2.8nM. |
|
V74471 | Taprostene (CG-4203) | 108945-35-3 | Taprostene (CG-4203) is a synthetic, chemically stable analog of prostacyclin (PGI2). |
|
V3336 | Terutroban | 165538-40-9 | Terutroban (S18886; S-18886) is a selective TP (thromboxane-prostaglandin receptor) receptor antagonist with antiplatelet activity and the potential to be used for the secondary prevention of acute thrombotic complications. |
|
V3370 | TG4-155 | 1164462-05-8 | TG4-155 is a novel, potent and brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less effective at EP4 (KB = 11.4 µM) and a panel of other receptors and channels. |
|
V28667 | Timapiprant sodium (OC000459) | 950688-14-9 | Timapiprant sodium (OC000459 sodium) is a potent, selective, and orally bioavailable D prostanoid receptor 2 (DP2, formerly known as CRTH2) antagonist with IC50 of 13 nM. |
|
V74487 | TP-16 | 2332972-26-4 | TP-16 is a new selective EP4 antagonist (inhibitor) with IC50 of 2.1nm. |
|
V74481 | trans-Isoferulic acid-d3 | 1028203-97-5 | trans-Isoferulic acid-d3 is the deuterated form of trans-Isoferulic acid. |
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