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Angiotensin Receptor

Angiotensin Receptor

Angiotensin II serves as the ligand for the class of G protein-coupled receptors known as angiotensin receptors. They play a crucial role in the renin-angiotensin system as they are involved in the signal transduction of the main effector hormone, angiotensin II's, vasoconstricting stimulus. Angiotensin II, their primary ligand, has a similar affinity for the AT1 and AT2 receptors. The angiotensin receptor that has been most thoroughly characterized is AT1. The fetus and newborn have a higher concentration of AT2 receptors. The AT3 and AT4 receptors are additional understudied subtypes.

Angiotensin Receptor related products

Structure Cat No. Product Name CAS No. Product Description
(D-Pro7)-Angiotensin I/II (1-7) V117308 (D-Pro7)-Angiotensin I/II (1-7) 586962-44-9 (D-Pro7)-angiotensin I/II (1-7) is a selective peptide angiotensin-(1-7) antagonist.
1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone V75301 1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone 120693-52-9 Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is an antagonist of angiotensin II receptor (IC50=48.2 μM).
15-Keto-PGA1 V103135 15-Keto-PGA1 61600-67-7 15-Keto-PGA1 is a metabolite of PGA1 and has a significant vasoconstrictive effect.
2-(Aminomethyl)-4-methylphenol hydrochloride V103250 2-(Aminomethyl)-4-methylphenol hydrochloride 2044714-53-4 2-(Aminomethyl)-4-methylphenol (5-methyl-2-HOBA) hydrochloride is an isoketanol scavenger that attenuates the hypertensive response to angiotensin II.
[Sar1, Ile8]-Angiotensin II TFA (AngiotensinII TFA; Angiotensin 2 TFA) V77338 [Sar1, Ile8]-Angiotensin II TFA (AngiotensinII TFA; Angiotensin 2 TFA) [Sar1, Ile8]-Angiotensin II (TFA) is a polypeptide that has multiple effects in vascular smooth muscle cells such as contraction of normal arteries, hypertrophy or proliferation of cultured cells or diseased blood vessels, etc.
[Tyr(P)4] Angiotensin II V75293 [Tyr(P)4] Angiotensin II 129785-85-9 [Tyr(P)4] Angiotensin II is a polypeptide that has multiple effects in vascular smooth muscle cells such as contraction of normal arteries, hypertrophy or proliferation of cultured cells or diseased blood vessels, etc.
Angiotensin I/BSA V103822 Angiotensin I/BSA Angiotensin I/BSA is an antigen-adjuvant conjugate of angiotensin I (angiotensin) combined with bovine serum albumin (BSA).
Angiotensin I/II (1-5) (TFA) V77261 Angiotensin I/II (1-5) (TFA) Angiotensin I/II 1-5 TFA is a polypeptide consisting of 1-5 amino acid (AA)s, converted from angiotensin I/II peptide.
Angiotensin I/II (1-6) (TFA) V77260 Angiotensin I/II (1-6) (TFA) Angiotensin I/II (1-6) TFA contains 1-6 amino acid (AA)s and is converted from angiotensin I/II peptide.
Angiotensin II (3-8), human TFA V77259 Angiotensin II (3-8), human TFA Angiotensin II (3-8), human (TFA) is a less active angiotensin AT1 receptor agonist (activator).
Angiotensin II/BSA V103823 Angiotensin II/BSA Angiotensin II/BSA is an antigen-adjuvant conjugate of angiotensin II (angiotensin) linked to bovine serum albumin (BSA).
Angiotensin III, human, mouse TFA V77258 Angiotensin III, human, mouse TFA Angiotensin III, human, mouse (TFA) is an angiotensin.
Angiotensinogen (1-13) (human) V75290 Angiotensinogen (1-13) (human) 82048-97-3 Angiotensinogen (1-13) (human) is a fragment of the renin substrate angiotensinogen, a naturally occurring renin substrate and the precursor of all angiotensin peptides
Antihypertensive agent 2 V79495 Antihypertensive agent 2 Antihypertensive agent 2 (Compound 4g) is an antihypertensive agent.
Antihypertensive agent 3 V78008 Antihypertensive agent 3 Antihypertensive agent 3 (compound 4a) is an angiotensin II receptor 1 antagonist.
AT1R antagonist 1 V75296 AT1R antagonist 1 2848719-80-0 AT1R antagonist 1 (compound 10) is a potent AT1R selective ligand.
AT1R antagonist 2 V75291 AT1R antagonist 2 2848719-76-4 AT1R antagonist 2 (compound 6) is a potent AT1R selective ligand.
AT1R antagonist 3 V86527 AT1R antagonist 3 AT1R antagonist 3 (Compound 1) is an antagonist of angiotensin II type 1 receptor (AT1R) and an inhibitor of L-type calcium channel CaV1.
AT1R antagonist 4 V112264 AT1R antagonist 4 2982582-16-9 AT1R antagonist 4 (Example 26) is an AT1R antagonist.
AT2 receptor ligand-1 V84474 AT2 receptor ligand-1
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