Angiotensin II serves as the ligand for the class of G protein-coupled receptors known as angiotensin receptors. They play a crucial role in the renin-angiotensin system as they are involved in the signal transduction of the main effector hormone, angiotensin II's, vasoconstricting stimulus. Angiotensin II, their primary ligand, has a similar affinity for the AT1 and AT2 receptors. The angiotensin receptor that has been most thoroughly characterized is AT1. The fetus and newborn have a higher concentration of AT2 receptors. The AT3 and AT4 receptors are additional understudied subtypes.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
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![N-[(乙基氨基)羰基]-3-[4-[(5-甲酰基-4-甲氧基-2-苯基-1H-咪唑-1-基)甲基]苯基]-5-异丁基-2-噻吩磺酰胺单钠盐](http://www.invivochem.com/upload/1124/V11930.png)
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V11930 | AVE-0991 sodium | 306288-04-0 | AVE0991 sodium, the sodium salt ofAVE-0991, is a novel, orally bioactivenon-peptide mimic and high affinity agonist of angiotensin-(1-7) with an IC50 of 21 nM. |
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V76724 | N-Acetyl-Ser-Asp-Lys-Pro acetate (Ac-SDKP acetate) | N-Acetyl-Ser-Asp-Lys-Pro (Ac-SDKP) acetate is a specific substrate for the N-terminal active site of angiotensin-converting enzyme (ACE). | |
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V76723 | N-Acetyl-Ser-Asp-Lys-Pro TFA (Ac-SDKP TFA) | N-Acetyl-Ser-Asp-Lys-Pro (TFA) is an endogenous tetrapeptide from bone marrow and is a specific substrate for the N-terminal site of ACE. | |
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V76694 | NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ | NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ is an ACE (angiotensin-converting enzyme) 2 (ACE2)-related peptide that may be utilized to study the function of ACE2. | |
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V102763 | NO-Losartan A | 791122-48-0 | NO-losartan A (compound 2a) exhibited vasodilatory effects due to the release of NO and antagonized the vasoconstrictive effects of angiotensin II with potency values similar to those of losartan. |
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V76691 | Norleual TFA | Norleual TFA is an angiotensin (Ang) IV analog and a hepatocyte growth factor (HGF)/c-Met inhibitor (antagonist) with IC50 of 3 pM. | |
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V75286 | Novokinin TFA | 1262750-59-3 | Novokinin TFA is a bioactive peptide agonist of the angiotensin AT2 receptor. |
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V106231 | Nva-VYIHPF | 51988-72-8 | Nva-VYIHPF is an angiotensin II analog. |
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V75297 | Olmesartan impurity | 154709-18-9 | Olmesartan impurity is the impurity of Olmesartan. |
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V75283 | Olmesartan lactone impurity | 849206-43-5 | Olmesartan impurity is the cyclic ester impurity of Olmesartan. |
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V75298 | Olmesartan medoxomil impurity C (Dehydro Olmesartan medoxomil) | 879562-26-2 | Olmesartan medoxomil impurity C is the impurity of Olmesartan medoxomil. |
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V75303 | Olmesartan methyl ester | 1347262-29-6 | Olmesartan methyl ester is an intermediate in the synthesis/preparation of Olmesartan medoxomil. |
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V4820 | Olodanrigan (PD126055; EMA 401) | 1316755-16-4 | Olodanrigan (EMA-401; PD-126055; EMA401) is a novel, orally bioavailable, peripherally restricted and highly selective AT2R (angiotensin II type 2 receptor) antagonist that can be potentially used for treatment of postherpetic neuralgia (PHN). |
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V2884 | PD-123319 TFA salt | 136676-91-0 | PD 123319 ditrifluoroacetate is a novel, potent, and selective nonpeptide AT2 (angiotensin II) receptor antagonist with IC50 of 34 nM. |
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V76477 | STIEEQAKTFLDKFNHEAEDLFYQSSLASWN | STIEEQAKTFLDKFNHEAEDLFYQSSLASWN is an ACE (angiotensin-converting enzyme) 2 (ACE2)-related peptide that may be utilized to study the function of ACE2. | |
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V81553 | Telmisartan-d4 (telmisartan d4) | Telmisartan-d4 is the deuterated form of Telmisartan. | |
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V86528 | Tetrahydro Aldosterone | 13489-75-3 | Tetrahydro Aldosterone is a steroid that inhibits adrenal angiotensin II receptors with an IC50 of 10 μM. |
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V75302 | TRV055 | 25849-90-5 | TRV055, a G protein-biased agonist, is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). |
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V76393 | TRV055 hydrochloride | TRV055 HCl, a G protein-biased agonist, is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). | |
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V75281 | TRV056 | 812644-79-4 | TRV056 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). |
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