Heat shock proteins (HSPs) are a class of functionally related proteins that are involved in the folding and unfolding of other proteins. HSPs are a group of proteins that are produced in response to heat shock. When cells are subjected to high temperatures or other stresses, HSP expression rises. This increase in expression is controlled by transcription. Heat shock factor (HSF) is primarily responsible for the dramatic upregulation of the heat shock proteins, which is a crucial component of the heat shock response. Nearly every living thing, from bacteria to people, contains HSPs. Heat shock proteins seem to play a big part in the cardiovascular system. There have been reports of the roles of Hsp90, Hsp84, Hsp70, Hsp27, Hsp20, and alpha B crystallin in the cardiovasculature.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V55775 | Palmitic acid-9,10-d2 (palmitic acid d2) | 78387-70-9 | Palmitic acid-9,10-d2 is the deuterated form of Palmitic acid. |
|
V53402 | Palmitic acid-d2 | 62689-96-7 | Palmitic acid-d2 is the deuterated form of Palmitic acid. |
|
V55773 | Palmitic acid-d2-1 (palmitic acid d2-1) | 62690-28-2 | Palmitic acid-d2-1 is the deuterated form of Palmitic acid. |
|
V55767 | Palmitic acid-d4 (palmitic acid d4) | 75736-49-1 | Palmitic acid-d4 is the deuterated form of Palmitic acid. |
|
V41027 | PDK-IN-1 | 2897696-10-3 | PDK-IN-1 (compound 7o) is a pyruvate dehydrogenase kinase (PDK) inhibitor. |
|
V77794 | PROTAC Hsp90α degrader 1 | PROTAC Hsp90α degrader 1 (Compound X10g) is a selective PROTAC Hsp90α degrader. | |
|
V36806 | SEW84 (SEW04784) | 259089-67-3 | SEW84 is an inhibitor (blocker/antagonist) of Aha1-stimulated Hsp90 (ASH) ATPase activity. |
|
V76517 | Shepherdin (79-87) (TFA) | Shepherdin (79-87) TFA is the 79 to 87 amino acid (AA) fragment of Shepherdin. | |
|
V81607 | TRAP1-IN-1 | TRAP1-IN-1 (compound 35) is a potent and specific inhibitor of TRAP1, the mitochondrial isoform of Hsp90. | |
|
V81608 | TRAP1-IN-2 | TRAP1-IN-2 (compound 36) is a selective degrader of TRAP1 downstream proteins without affecting the cytoplasmic downstream proteins of Hsp90. | |
|
V35107 | YM-1 | 409086-68-6 | YM-1 is stable and soluble MKT-077. |
|
V2274 | YUM70 | 423145-35-1 | YUM70 (YUM-70) is a novel and potent GRP78 (glucose-regulated protein 78) inhibitor (IC50=1.5 μM) with anticancer activity. |
|
V73469 | Zelavespib hydrochloride (PU-H71 hydrochloride) | Zelavespib (PU-H71) HCl is a potent Hsp90 inhibitor (antagonist) with IC50 of 51 nM against Hsp90 in MDA-MB-468 cells. |
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