White blood cells (leukocytes), which are a subset of cytokines (secreted proteins and signaling molecules), were the first to be observed to express interleukins. Interleukins are crucial for the immune system's proper operation, and there have been rare cases of their deficiency that have all been associated with autoimmune disorders or immune deficiencies. Helper CD4 T lymphocytes, along with monocytes, macrophages, and endothelial cells, produce the majority of interleukins. They support the growth and differentiation of hematopoietic cells, including T and B lymphocytes. The development of spatial memories in mice has also been linked to interleukin receptors on astrocytes in the hippocampus.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V121189 | (+)-LRH-1 agonist-2 | (+)-LRH-1 agonist-2 is a stereoisomer of LRH-1 modulator-1. | |
|
V93148 | (+)-LRH-1 modulator-1 | (+)-LRH-1 modulator-1 is a stereoisomer of LRH-1 modulator-1. | |
|
V121638 | (6R,7R)-Epoxy-1-oleanen-3-ol | 1609645-89-7 | (6R,7R)-Epoxy-1-oleanen-3-ol is a triterpenoid compound found in Boswellia ovalifoliolata and has anti-inflammatory activity. |
|
V121809 | (E/Z)-OSM-SMI-8 | (E/Z)-OSM-SMI-8 is the racemic form of OSM-SMI-8. | |
|
V75015 | (R)-TCB2 | 912342-36-0 | (R)-TCB2 is the R-enantiomer of TCB2. |
|
V122035 | (rac)-Poriol | 70460-58-1 | The racemic mixture (5,7,4'-trihydroxy-6-methylflavanone) exhibits antioxidant activity and can scavenge the free radical DPPH with an IC50 value of 0.18 µg/mL. |
|
V123720 | 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole | 484678-79-7 | 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole is a carbazole alkaloid that can be isolated from Murraya koenigii. |
|
V109470 | 1-Tetradecanol-d7 | 1-Tetradecyl-d7 is a deuterated derivative of 1-tetradecyl alcohol. | |
|
V122960 | 10(11)-Cl-BBQ | 10(11)-Cl-BBQ is a high-affinity aryl receptor (AhR) agonist. | |
|
V75016 | 12-Dehydrogingerdione (12-DHGD) | 99742-05-9 | 12-Dehydrogingerdione is an inhibitor (blocker/antagonist) of NO Synthase. |
|
V125278 | 36R-D481 | 36R-D481 is a competitive antagonist of IL-36R that can effectively inhibit IL-36 signaling. | |
|
V126057 | 4,5-Dehydro-6-oxoallosecurinine | 4,5-Dehydro-6-oxoallosecurinine is a Keap1-Nrf2 pathway activator. | |
|
V112315 | 4-Ethoxybenzaldehyde | 10031-82-0 | 4-Ethoxybenzaldehyde (p-ethoxybenzaldehyde) is a derivative of benzaldehyde. |
|
V74366 | 4-Methoxylonchocarpin | 51589-67-4 | 4-Methoxylonchocarpin is an orally bioactive anti-inflammatory agent. |
|
V126428 | 4L2-P13D | 4L2-P13D is an IL-11 antagonist with an IC50 value of 2.8 μM. | |
|
V127035 | 5-Hydroxy-6,7-dimethoxyflavone | 2035-05-4 | 5-Hydroxy-6,7-dimethoxyflavone is an orally effective inhibitor of ferroptosis. |
|
V127615 | 7-O-Methyl glabranin | 75291-75-7 | 7-O-Methyl glabranin is a flavonoid compound and an inhibitor of LPS-induced TNF-α and IL-1β production. |
|
V127960 | a15:0-i15:0 PE | 2936622-21-6 | a15:0-i15:0 PE is a diacylphosphatidylethanolamine with two branched chains. |
|
V119595 | Abdakibart | 3034641-53-4 | Abdakibart is a humanized IgG4 monoclonal antibody inhibitor that targets IL-1β. |
|
V128045 | ABM-125 | ABM-125 is an IL-25 neutralizer and an immunomodulator. |
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