Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V24687 | Peldesine dihydrochloride (BCX 34 dihydrochloride) | 2772702-10-8 | Peldesine (BCX 34) di-HCl is a potent, competitive, reversible and orally bioactive purine nucleoside phosphorylase (PNP) inhibitor (antagonist) with IC50 of 36 for human, rat and mouse red blood cell (RBC) PNP, respectively. |
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V83096 | Pimeloylarginine | ||
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V55277 | Purine riboside triphosphate (PTP) | 23197-96-8 | Purine riboside triphosphate is a triphosphate analogue of purine nucleoside. |
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V75670 | Purine-9-bD-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside | 132723-01-4 | Purine-9-bD-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside is an analogue of purine nucleoside. |
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V55409 | Py-MAA-Val-Cit-PAB-DX8951 | 2504068-37-3 | Py-MAA-Val-Cit-PAB-DX8951 is a purine toxin. |
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V55644 | Rev 2'-O-MOE-5MeU-5'-amidite | 1345715-43-6 | Rev 2'-O-MOE-5MeU-5'-amidite is an analogue of purine nucleoside. |
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V55630 | Rev 2'-O-MOE-G(iBu)-5'-amidite | 725223-44-9 | Rev 2'-O-MOE-G(iBu)-5'-amidite is an analogue of purine nucleoside. |
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V83097 | Suberylarginine | ||
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V75951 | Thymine 1-β-D-arabinofuranoside | 605-23-2 | Thymine 1-β-D-arabinofuranoside is an analogue of purine nucleoside. |
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V51765 | TLR7 agonist 10 | 2389988-34-3 | TLR7 agonist 10 is a purine nucleoside analog. |
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V51763 | TLR7 agonist 13 | 2389988-70-7 | TLR7 agonist 13 is a purine nucleoside analog. |
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V75655 | Uridine 5-oxyacetic acid methyl ester | 66536-81-0 | Uridine 5-oxyacetic acid methyl ester is an analogue of purine nucleoside. |
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V53227 | Uridine triphosphate-13C9,15N2 sodium (UTP-13C9,15N2 (sodium); Uridine 5'-triphosphate-13C9,15N2 (sodium)) | 285978-18-9 | Uridine triphosphate-13C9,15N2 (sodium) is an isotopically labeled Uridine triphosphate sodium. |
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V55605 | Uridine-5-oxyacetic acid | 28144-25-4 | Uridine-5-oxyacetic acid is an analogue of purine nucleoside. |
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V75546 | α-Azidothymidine | 59090-48-1 | α-Azidothymidine is an analogue of purine nucleoside. |
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V75904 | α-Cytidine | 13913-16-1 | α-Cytidine is an analogue of purine nucleoside. |
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V56819 | Deoxyribonucleic acid sodium salt | 438545-06-3 | eoxyribonucleic acid sodium salt from salmon testes |
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